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With the remarkable success of large language models (LLMs) in natural language understanding and generation, multimodal large language models (MLLMs) have rapidly advanced in their ability to process data across multiple modalities. While…
Whole Slide Imaging (WSI) has become a gold standard in cancer diagnosis, inspecting multi-scale information from cellular to tissue levels. Processing an entire WSI directly is infeasible due to GPU memory constraints; thus, Multiple…
While long-context large language models (LLMs) exhibit remarkable document processing capabilities, their prohibitively high training costs often hinder customized applications. To mitigate this issue, we propose \textit{Sequential…
The rapid digitization of histopathology slides has opened up new possibilities for computational tools in clinical and research workflows. Among these, content-based slide retrieval stands out, enabling pathologists to identify…
Batch effects arising from technical variations in histopathology staining protocols, scanners, and acquisition pipelines pose a persistent challenge for computational pathology, hindering cross-batch generalization and limiting reliable…
With the advancement of Large Language Model (LLM) for natural language processing, this paper presents an intriguing finding: a frozen pre-trained LLM layer can process visual tokens for medical image segmentation tasks. Specifically, we…
With the wide adoption of language models for IR -- and specifically RAG systems -- the latency of the underlying LLM becomes a crucial bottleneck, since the long contexts of retrieved passages lead large prompts and therefore, compute…
The escalating computational costs of Large Language Model (LLM) inference have become a critical barrier to their widespread and sustainable deployment. While existing optimization strategies are effective, they are predominantly based on…
Multiple instance learning (MIL) has become a preferred method for gigapixel whole slide image (WSI) classification without requiring patch-level annotations. Current MIL research primarily relies on embedding-based approaches, which…
Weakly supervised semantic segmentation (WSSS) in histopathology reduces pixel-level labeling by learning from image-level labels, but it is hindered by inter-class homogeneity, intra-class heterogeneity, and CAM-induced region shrinkage…
Recently, scaling images to high resolution has received much attention in multimodal large language models (MLLMs). Most existing practices adopt a sliding-window-style cropping strategy to adapt to resolution increase. Such a cropping…
Digital pathology has revolutionized the field by enabling the digitization of tissue samples into whole slide images (WSIs). However, the high resolution and large size of WSIs present significant challenges when it comes to applying Deep…
Representation learning of pathology whole-slide images (WSIs) has been has primarily relied on weak supervision with Multiple Instance Learning (MIL). However, the slide representations resulting from this approach are highly tailored to…
Vision-Language Models (VLMs) face severe memory and latency bottlenecks due to high-resolution visual tokens. While current token reduction methods theoretically save FLOPs, post-hoc pruning introduces structural overhead, failing to yield…
Efficient adaption of large language models (LLMs) on edge devices is essential for applications requiring continuous and privacy-preserving adaptation and inference. However, existing tuning techniques fall short because of the high…
Advances in optical microscopy scanning have significantly contributed to computational pathology (CPath) by converting traditional histopathological slides into whole slide images (WSIs). This development enables comprehensive digital…
Vision-Language Models (VLMs) are expensive because the LLM processes hundreds of largely redundant visual tokens. Existing token reduction methods typically exploit \textit{either} vision-encoder saliency (broad but query-agnostic)…
Commonsense reasoning often requires both textual and visual knowledge, yet Large Language Models (LLMs) trained solely on text lack visual grounding (e.g., "what color is an emperor penguin's belly?"). Visual Language Models (VLMs) perform…
Recent advances in artificial intelligence (AI), in particular self-supervised learning of foundation models (FMs), are revolutionizing medical imaging and computational pathology (CPath). A constant challenge in the analysis of digital…
Current cervical cytopathology whole slide image (WSI) screening primarily relies on detection-based approaches, which are limited in performance due to the expense and time-consuming annotation process. Multiple Instance Learning (MIL), a…