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We consider the dynamics of a virus spreading through a population that produces a mutant strain with the ability to infect individuals that were infected with the established strain. Temporary cross-immunity is included using a time delay,…

Populations and Evolution · Quantitative Biology 2023-02-16 Bruce Pell , Samantha Brozak , Tin Phan , Fuqing Wu , Yang Kuang

CoV2019 has evolved to be much more dangerous than CoV2003. Experiments suggest that structural rearrangements dramatically enhance CoV2019 activity. We identify a new first stage of infection which precedes structural rearrangements by…

Other Quantitative Biology · Quantitative Biology 2021-07-14 J. C. Phillips

The global SARS-CoV-2 pandemic suggests a novel type of disease spread dynamics. WHO states that there is currently no evidence that people who have recovered from COVID-19 and have antibodies are immune from a second infection [WHO].…

Physics and Society · Physics 2020-08-03 Kurt Langfeld

Traditional studies about disease dynamics have focused on global stability issues, due to their epidemiological importance. We study a classical SIR-SI model for arboviruses in two different directions: we begin by describing an…

Populations and Evolution · Quantitative Biology 2014-08-28 Max O. Souza

This paper is concerned with a family of Reaction-Diffusion systems that we introduced in [15], and that generalizes the SIR type models from epidemiology. Such systems are now also used to describe collective behaviors.In this paper, we…

Analysis of PDEs · Mathematics 2021-02-16 Henri Berestycki , Samuel Nordmann , Luca Rossi

This paper is devoted to the multidisciplinary modelling of a pandemic initiated by an aggressive virus, specifically the so-called \textit{SARS--CoV--2 Severe Acute Respiratory Syndrome, corona virus n.2}. The study is developed within a…

The paper develops a stochastic Agent-Based Model (ABM) mimicking the spread of infectious diseases in geographical domains. The model is designed to simulate the spatiotemporal spread of SARS-CoV2 disease, known as COVID-19. Our…

Physics and Society · Physics 2020-07-28 Masoud Jalayer , Carlotta Orsenigo , Carlo Vercellis

A significant proportion of the infections driving the current {SARS-CoV-2} pandemic are transmitted asymptomatically. Here we introduce and study a simple epidemic model with separate compartments comprising asymptomatic and symptomatic…

Populations and Evolution · Quantitative Biology 2022-10-12 Maurice Görtz , Joachim Krug

This paper presents a critical analysis of the literature and perspective research ideas for modeling the epidemics caused by the SARS-CoV-2 virus. It goes beyond deterministic population dynamics to consider several key complexity features…

Populations and Evolution · Quantitative Biology 2025-01-24 Giulia Bertaglia , Andrea Bondesan , Diletta Burini , Raluca Eftimie , Lorenzo Pareschi , Giuseppe Toscani

We propose two stochastic models for the Coronavirus pandemic. The statistical properties of the models, in particular the correlation functions and the probability density function, have duly been computed. Our models, which generalises a…

Medical Physics · Physics 2020-12-04 Giorgio Sonnino , Fernando Mora , Pasquale Nardone

The scope of this work is to serve as a guiding tool against subjective estimations on real pandemic situations (mainly due to the inability to acquire objective real data over whole populations). The previously introduced model of closed…

Physics and Society · Physics 2020-05-18 Y. Contoyiannis , S. G. Stavrinides , M. P. Hanias , M. Kampitakis , P. Papadopoulos , S. Potirakis

Stochastic differential equations characterized by uncertainty are effective in modelling virus dynamics and provide an alternative to traditional deterministic models. Epidemic models are inevitably subjected to the randomness within the…

Dynamical Systems · Mathematics 2024-08-12 Bishal Chhetri , B. V. Ratish Kumar

More than any other infectious disease epidemic, the COVID-19 pandemic has been characterized by the generation of large volumes of viral genomic data at an incredible pace due to recent advances in high-throughput sequencing technologies,…

RNA virus (e.g., SARS-CoV-2) evolves in a complex manner. Studying RNA virus evolution is vital for understanding molecular evolution and medicine development. Scientists lack, however, general frameworks to characterize the dynamics of RNA…

Populations and Evolution · Quantitative Biology 2022-04-20 Xiaofei Ge , Kaichao You , Zeren Tan , Hedong Hou , Yang Tian , Pei Sun

Mathematical models are formal and simplified representations of the knowledge related to a phenomenon. In classical epidemic models, a neglected aspect is the heterogeneity of disease transmission and progression linked to the viral load…

Physics and Society · Physics 2022-05-10 Rossella Della Marca , Nadia Loy , Andrea Tosin

This paper presents a detailed mathematical investigation into the dynamics of COVID-19 infections through extended Susceptible-Infected-Recovered (SIR) and Susceptible-Exposed-Infected-Recovered (SEIR) epidemiological models. By…

Populations and Evolution · Quantitative Biology 2025-05-21 Caleb Traxler , Minh Ton , Nameer Ahmed , Sasha Prostota , Annie Cheng

Contemporary epidemiological models often involve spatial variation, providing an avenue to investigate the averaged dynamics of individual movements. In this work, we extend a recent model by Vaziry, Kolokolnikov, and Kevrekidis [Royal…

Populations and Evolution · Quantitative Biology 2024-10-01 Maryam Ahmadpoortorkamani , Alexei Cheviakov

The discovery of SARS-CoV-2, the responsible virus for the Covid-19 epidemic, has sparked a global health concern with many countries affected. Developing models that can interpret the epidemic and give common trend parameters are useful…

Populations and Evolution · Quantitative Biology 2021-09-21 Milad Radiom , Jean-Franccois Berret

The acute phase of the Covid-19 pandemic has made apparent the need for decision support based upon accurate epidemic modeling. This process is substantially hampered by under-reporting of cases and related data incompleteness issues. In…

Applications · Statistics 2026-03-10 Anastasios Apsemidis , Nikolaos Demiris