CoV2019 has evolved to be much more dangerous than CoV2003. Experiments suggest that structural rearrangements dramatically enhance CoV2019 activity. We identify a new first stage of infection which precedes structural rearrangements by using biomolecular evolutionary theory to identify sequence differences enhancing viral attachment rates. We find a small cluster of mutations which show that CoV-2 has a new feature that promotes much stronger viral attachment and enhances contagiousness. The extremely dangerous dynamics of human coronavirus infection is a dramatic example of evolutionary approach of self-organized networks to criticality. It may favor a very successful vaccine. The identified mutations can be used to test the present theory experimentally.
@article{arxiv.2008.12168,
title = {Synchronized Attachment and the Darwinian Evolution of Coronaviruses CoV-1 and CoV-2},
author = {J. C. Phillips},
journal= {arXiv preprint arXiv:2008.12168},
year = {2021}
}