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Modern scientific instruments operate under increasingly extreme constraints on bandwidth, latency, and power. Inference at the sensor edge determines experimental data collection efficiency by deciding which information to save for further…

The movement of molecules inside living cells is a fundamental feature of biological processes. The ability to both observe and analyse the details of molecular diffusion in vivo at the single molecule and single cell level can add…

Quantitative Methods · Quantitative Biology 2012-11-21 Alex Robson , Kevin Burrage , Mark Leake

We present a new particle tracking software algorithm designed to accurately track the motion of low-contrast particles against a background with large variations in light levels. The method is based on a polynomial fit of the intensity…

Soft Condensed Matter · Physics 2009-11-13 Salman S. Rogers , Thomas A. Waigh , Xiubo Zhao , Jian R. Lu

We propose an approach to analysing single trajectories of a particle, which moves randomly on a landscape distinct parts of which result in sufficiently various diffusion coefficients. The method based on the mapping the cumulative sum of…

Biological Physics · Physics 2019-09-04 Eugene B. Postnikov , Igor M. Sokolov

A dual-excitation method for resonant-frequency tracking in scanning probe microscopy based on amplitude detection is developed. This method allows the cantilever to be operated at or near resonance for techniques where standard phase…

Materials Science · Physics 2008-03-13 B J Rodriguez , C Callahan , S V Kalinin , R Proksch

The prospect of pileup induced backgrounds at the High Luminosity LHC (HL-LHC) has stimulated intense interest in technology for charged particle timing at high rates\cite{challenge}. In this paper I report on a framework for fast timing…

Instrumentation and Detectors · Physics 2018-12-05 Sebastian White

Despite significant advances in particle imaging technologies over the past two decades, few advances have been made in particle tracking, i.e. linking individual particle positions across time series data. The state-of-the-art tracking…

Soft Condensed Matter · Physics 2022-01-25 Ella M. King , Zizhao Wang , David A. Weitz , Frans Spaepen , Michael P. Brenner

Comprehensive characterization of nanomaterials for medical applications is a challenging and complex task due to the multitude of parameters which need to be taken into consideration in a broad range of conditions. Routine methods such as…

Single particle tracking systems monitor cellular processes with great accuracy in nano-biological systems. The emissions of the fluorescent molecules are detected with cameras or photodetectors. However, state-of-the-art imaging systems…

Quantitative Methods · Quantitative Biology 2018-05-16 Burhan Gulbahar , Gorkem Memisoglu

Localization of single fluorescent molecules is key for physicochemical and biophysical measurements such as single-molecule tracking and super-resolution imaging by single-molecule localization microscopy (SMLM). Recently a series of…

Optics · Physics 2021-09-06 Luciano A. Masullo , Lucía F. Lopez , Fernando D. Stefani

We describe a method to track particles undergoing large displacements. Starting with a list of particle positions sampled at different time points, we assign particle identities by minimizing the sum across all particles of the trace of…

Soft Condensed Matter · Physics 2016-09-02 Rostislav Boltyanskiy , Jason W. Merrill , Eric R. Dufresne

We study the effect of spatially-varying potential and diffusivity on the dispersion of a tracer particle in single-file diffusion. Non-interacting particles in such a system exhibit normal diffusion at late times, which is characterised by…

Statistical Mechanics · Physics 2025-09-15 Benjamin Sorkin , David S. Dean

Scattering-based single-particle tracking (S-SPT) has opened new avenues for highly sensitive label-free detection and characterization of nanoscopic objects, making it particularly attractive for various analytical applications. However, a…

Geochemical systems are known to exhibit highly variable spatiotemporal behavior. This may be observed both in non-smooth concentration curves in space for a single sampling time and also in variability between samples taken from the same…

In this paper we present a novel approach to FEL simulations based on the decomposition of the electromagnetic field in a finite number of radiation modes. The evolution of each mode amplitude is simply determined by energy conservation.…

Accelerator Physics · Physics 2020-11-18 A. Fisher , P. Musumeci , S. B. Van der Geer

Protein phosphorylation provides a dynamic readout of cellular signaling yet remains difficult to detect at low abundance and stoichiometry. Single-molecule surface-enhanced Raman spectroscopy (SM-SERS) using particle-in-pore plasmonic…

Mesoscale and Nanoscale Physics · Physics 2026-04-09 Mulusew W. Yaltaye , Yingqi Zhao , Kuo Zhan , Vahid Farrahi , Jian-An Huang

Determining a beam's full trajectory requires tracking both its position and momentum (angular) information. However, the product of position and momentum uncertainty in a simultaneous measurement of the two parameters is bound by the…

The increasing use of microfluidics in industrial, biomedical, and clinical applications requires a more and more precise control of the microfluidic flows and suspended particles or cells. This leads to higher demands in three-dimensional…

Fluid Dynamics · Physics 2020-11-10 Massimiliano Rossi , Rune Barnkob

Photoelectron momentum microscopy is an emerging powerful method for angle-resolved photoelectron spectroscopy (ARPES), especially in combination with imaging spin filters. These instruments record kx-ky images, typically exceeding a full…

Applied Physics · Physics 2021-02-03 G. Schoenhense , S. Babenkov , D. Vasilyev , H. -J. Elmers , K. Medjanik

A particle tracking velocimetry apparatus is presented that is capable of measuring three-dimensional particle trajectories across large volumes, of the order of several meters, during natural snowfall events. Field experiments, aimed at…

Fluid Dynamics · Physics 2023-04-12 Nathaniel Bristow , Jiaqi Li , Peter Hartford , Michele Guala , Jiarong Hong
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