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Purpose: (1) To develop a deep learning algorithm to automatically segment structures of the optic nerve head (ONH) and macula in 3D wide-field optical coherence tomography (OCT) scans; (2) To assess whether 3D macula or ONH structures (or…

Glaucoma is a leading cause of irreversible vision impairment globally and cases are continuously rising worldwide. Early detection is crucial, allowing timely intervention which can prevent further visual field loss. To detect glaucoma,…

Glaucoma is one of the primary causes of vision loss around the world, necessitating accurate and efficient detection methods. Traditional manual detection approaches have limitations in terms of cost, time, and subjectivity. Recent…

Image and Video Processing · Electrical Eng. & Systems 2023-11-03 Aized Amin Soofi , Fazal-e-Amin

Glaucoma is a leading cause of irreversible blindness, but early detection can significantly improve treatment outcomes. Traditional diagnostic methods are often invasive and require specialized equipment. In this work, we present a deep…

Computer Vision and Pattern Recognition · Computer Science 2025-06-30 Rishiraj Paul Chowdhury , Nirmit Shekar Karkera

Objective: (1) To assess whether ONH biomechanics improves prediction of three progressive visual field loss patterns in glaucoma; (2) to use explainable AI to identify strain-sensitive ONH regions contributing to these predictions.…

Objectives: To evaluate the performance of a deep learning based Artificial Intelligence (AI) software for detection of glaucoma from stereoscopic optic disc photographs, and to compare this performance to the performance of a large cohort…

Computer Vision and Pattern Recognition · Computer Science 2019-06-05 Thomas W. Rogers , Nicolas Jaccard , Francis Carbonaro , Hans G. Lemij , Koenraad A. Vermeer , Nicolaas J. Reus , Sameer Trikha

Precis: A hybrid deep-learning model combines NFL reflectance and other OCT parameters to improve glaucoma diagnosis. Objective: To investigate if a deep learning model could be used to combine nerve fiber layer (NFL) reflectance and other…

Image and Video Processing · Electrical Eng. & Systems 2024-06-07 Ou Tan , David S. Greenfield , Brian A. Francis , Rohit Varma , Joel S. Schuman , David Huang , Dongseok Choi

One of the leading causes of blindness is glaucoma, which is challenging to detect since it remains asymptomatic until the symptoms are severe. Thus, diagnosis is usually possible until the markers are easy to identify, i.e., the damage has…

Image and Video Processing · Electrical Eng. & Systems 2021-10-05 Sayan Mandal , Alessandro A. Jammal , Felipe A. Medeiros

The estimation of glaucoma progression is a challenging task as the rate of disease progression varies among individuals in addition to other factors such as measurement variability and the lack of standardization in defining progression.…

Glaucoma is a leading cause of irreversible blindness worldwide, emphasizing the critical need for early detection and intervention. In this paper, we present DeepEyeNet, a novel and comprehensive framework for automated glaucoma detection…

Computer Vision and Pattern Recognition · Computer Science 2025-01-22 Angshuman Roy , Anuvab Sen , Soumyajit Gupta , Soham Haldar , Subhrajit Deb , Taraka Nithin Vankala , Arkapravo Das

Glaucoma leads to permanent vision disability by damaging the optical nerve that transmits visual images to the brain. The fact that glaucoma does not show any symptoms as it progresses and cannot be stopped at the later stages, makes it…

Image and Video Processing · Electrical Eng. & Systems 2021-09-29 Ozer Can Devecioglu , Junaid Malik , Turker Ince , Serkan Kiranyaz , Eray Atalay , Moncef Gabbouj

Glaucoma is a complex group of eye diseases marked by optic nerve damage, commonly linked to elevated intraocular pressure and biomarkers like retinal nerve fiber layer thickness. Understanding how these biomarkers interact is crucial for…

Image and Video Processing · Electrical Eng. & Systems 2025-09-24 Cheng Huang , Weizheng Xie , Tsengdar Lee , Karanjit Kooner , Ning Zhang , Jia Zhang

Recently, the attention mechanism has been successfully applied in convolutional neural networks (CNNs), significantly boosting the performance of many computer vision tasks. Unfortunately, few medical image recognition approaches…

Computer Vision and Pattern Recognition · Computer Science 2019-04-23 Liu Li , Mai Xu , Xiaofei Wang , Lai Jiang , Hanruo Liu

Automatic evaluation of the retinal fundus image is emerging as one of the most important tools for early detection and treatment of progressive eye diseases like Glaucoma. Glaucoma results to a progressive degeneration of vision and is…

Image and Video Processing · Electrical Eng. & Systems 2021-12-13 Sneha Dasgupta , Rishav Mukherjee , Kaushik Dutta , Anindya Sen

A major cause of irreversible visual impairment is angle-closure glaucoma, which can be screened through imagery from Anterior Segment Optical Coherence Tomography (AS-OCT). Previous computational diagnostic techniques address this…

Computer Vision and Pattern Recognition · Computer Science 2018-09-11 Huazhu Fu , Yanwu Xu , Stephen Lin , Damon Wing Kee Wong , Baskaran Mani , Meenakshi Mahesh , Tin Aung , Jiang Liu

Glaucoma is one of the most severe eye diseases, characterized by rapid progression and leading to irreversible blindness. It is often the case that diagnostics is carried out when one's sight has already significantly degraded due to the…

Image and Video Processing · Electrical Eng. & Systems 2022-08-02 Ahmed Al Mahrooqi , Dmitrii Medvedev , Rand Muhtaseb , Mohammad Yaqub

Glaucoma is a prevalent eye disease that progresses silently without symptoms. If not detected and treated early, it can cause permanent vision loss. Computer-assisted diagnosis systems play a crucial role in timely and efficient…

Computer Vision and Pattern Recognition · Computer Science 2025-02-25 Mustafa Yurdakul , Kubra Uyar , Sakir Tasdemir

Differences in image quality, lighting conditions, and patient demographics pose challenges to automated glaucoma detection from color fundus photography. Brighteye, a method based on Vision Transformer, is proposed for glaucoma detection…

Computer Vision and Pattern Recognition · Computer Science 2024-09-30 Hui Lin , Charilaos Apostolidis , Aggelos K. Katsaggelos

Glaucoma is a top cause of irreversible blindness globally, making early detection and longitudinal follow-up pivotal to preventing permanent vision loss. Current screening and progression assessment, however, rely on single tests or…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Wenbin Wei , Suyuan Yao , Cheng Huang , Xiangyu Gao

Purpose: The optic nerve head (ONH) undergoes complex and deep 3D morphological changes during the development and progression of glaucoma. Optical coherence tomography (OCT) is the current gold standard to visualize and quantify these…

Image and Video Processing · Electrical Eng. & Systems 2022-04-21 Fabian A. Braeu , Alexandre H. Thiéry , Tin A. Tun , Aiste Kadziauskiene , George Barbastathis , Tin Aung , Michaël J. A. Girard