Glaucoma is a leading cause of irreversible blindness, but early detection can significantly improve treatment outcomes. Traditional diagnostic methods are often invasive and require specialized equipment. In this work, we present a deep learning pipeline using the EfficientNet-B0 architecture for glaucoma detection from retinal fundus images. Unlike prior studies that rely on single datasets, we sequentially train and fine-tune our model across ACRIMA, ORIGA, and RIM-ONE datasets to enhance generalization. Our experiments show that minimal preprocessing yields higher AUC-ROC compared to more complex enhancements, and our model demonstrates strong discriminative performance on unseen datasets. The proposed pipeline offers a reproducible and scalable approach to early glaucoma detection, supporting its potential clinical utility.
@article{arxiv.2506.21770,
title = {Early Glaucoma Detection using Deep Learning with Multiple Datasets of Fundus Images},
author = {Rishiraj Paul Chowdhury and Nirmit Shekar Karkera},
journal= {arXiv preprint arXiv:2506.21770},
year = {2025}
}
Comments
13 pages, 6 figures, prepared for course CSCI 5922 at University of Colorado Boulder. Code available upon request, dataset taken from Kaggle