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Identifying disease-indicative genes is critical for deciphering disease mechanisms and has attracted significant interest in biomedical research. Spatial transcriptomics offers unprecedented insights for the detection of disease-specific…

Methodology · Statistics 2024-09-05 Qicheng Zhao , Qihuang Zhang

Robust generalization beyond training distributions remains a critical challenge for deep neural networks. This is especially pronounced in medical image analysis, where data is often scarce and covariate shifts arise from different…

Computer Vision and Pattern Recognition · Computer Science 2026-02-04 Francesco Di Salvo , Sebastian Doerrich , Jonas Alle , Christian Ledig

Hyperspectral image (HSI) classification presents inherent challenges due to high spectral dimensionality, significant domain shifts, and limited availability of labeled data. To address these issues, we propose a novel Active Transfer…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Muhammad Ahmad , Francesco Mauro , Manuel Mazzara , Salvatore Distefano , Adil Mehmood Khan , Silvia Liberata Ullo

Spatial transcriptomics has revolutionized tissue analysis by simultaneously mapping gene expression, spatial topography, and histological context across consecutive tissue sections, enabling systematic investigation of spatial…

Applications · Statistics 2025-10-24 Meng Zhou , Shuangge Ma , Mengyun Wu

Image-text representation learning forms a cornerstone in vision-language models, where pairs of images and textual descriptions are contrastively aligned in a shared embedding space. Since visual and textual concepts are naturally…

Computer Vision and Pattern Recognition · Computer Science 2025-03-04 Avik Pal , Max van Spengler , Guido Maria D'Amely di Melendugno , Alessandro Flaborea , Fabio Galasso , Pascal Mettes

Metric learning plays a critical role in training image retrieval and classification. It is also a key algorithm in representation learning, e.g., for feature learning and its alignment in metric space. Hyperbolic embedding has been…

Computer Vision and Pattern Recognition · Computer Science 2023-10-24 Shiyang Yan , Zongxuan Liu , Lin Xu

Spatially resolved transcriptomics (ST) measures gene expression along with the spatial coordinates of the measurements. The analysis of ST data involves significant computation complexity. In this work, we propose gene expression…

Genomics · Quantitative Biology 2022-05-24 Zhuoyan Xu , Kris Sankaran

Image fusion combines data from different heterogeneous sources to obtain more precise information about an underlying scene. Hyperspectral-multispectral (HS-MS) image fusion is currently attracting great interest in remote sensing since it…

Computer Vision and Pattern Recognition · Computer Science 2022-11-28 Ricardo Augusto Borsoi , Tales Imbiriba , José Carlos Moreira Bermudez

The fast development of self-supervised learning lowers the bar learning feature representation from massive unlabeled data and has triggered a series of research on change detection of remote sensing images. Challenges in adapting…

Computer Vision and Pattern Recognition · Computer Science 2022-12-07 Meiqi Hu , Chen Wu , Liangpei Zhang

Hyperspectral imaging can help better understand the characteristics of different materials, compared with traditional image systems. However, only high-resolution multispectral (HrMS) and low-resolution hyperspectral (LrHS) images can…

Computer Vision and Pattern Recognition · Computer Science 2019-01-11 Qi Xie , Minghao Zhou , Qian Zhao , Deyu Meng , Wangmeng Zuo , Zongben Xu

The inclusion of spatial information into spectral classifiers for fine-resolution hyperspectral imagery has led to significant improvements in terms of classification performance. The task of spectral-spatial hyperspectral image…

Computer Vision and Pattern Recognition · Computer Science 2021-09-08 Puhong Duan , Pedram Ghamisi , Xudong Kang , Behnood Rasti , Shutao Li , Richard Gloaguen

Crime has become a major concern in many cities, which calls for the rising demand for timely predicting citywide crime occurrence. Accurate crime prediction results are vital for the beforehand decision-making of government to alleviate…

Machine Learning · Computer Science 2022-08-19 Zhonghang Li , Chao Huang , Lianghao Xia , Yong Xu , Jian Pei

Spatial transcriptomics (ST) is an emerging technology that enables medical computer vision scientists to automatically interpret the molecular profiles underlying morphological features. Currently, however, most deep learning-based ST…

Computer Vision and Pattern Recognition · Computer Science 2024-12-05 Junchao Zhu , Ruining Deng , Tianyuan Yao , Juming Xiong , Chongyu Qu , Junlin Guo , Siqi Lu , Mengmeng Yin , Yu Wang , Shilin Zhao , Haichun Yang , Yuankai Huo

Predicting spatial gene expression from H&E histology offers a scalable and clinically accessible alternative to sequencing, but realizing clinical impact requires models that generalize across cancer types and capture biologically coherent…

Machine Learning · Computer Science 2026-02-10 Susu Hu , Qinghe Zeng , Nithya Bhasker , Jakob Nikolas Kather , Stefanie Speidel

Data representation in non-Euclidean spaces has proven effective for capturing hierarchical and complex relationships in real-world datasets. Hyperbolic spaces, in particular, provide efficient embeddings for hierarchical structures. This…

Computer Vision and Pattern Recognition · Computer Science 2024-09-27 Jacob Fein-Ashley , Ethan Feng , Minh Pham

Hyperspectral imaging (HSI) is an advanced sensing modality that simultaneously captures spatial and spectral information, enabling non-invasive, label-free analysis of material, chemical, and biological properties. This Primer presents a…

Computer Vision and Pattern Recognition · Computer Science 2026-02-10 Danfeng Hong , Chenyu Li , Naoto Yokoya , Bing Zhang , Xiuping Jia , Antonio Plaza , Paolo Gamba , Jon Atli Benediktsson , Jocelyn Chanussot

Because hyperspectral remote sensing images contain a lot of redundant information and the data structure is highly non-linear, leading to low classification accuracy of traditional machine learning methods. The latest research shows that…

Computer Vision and Pattern Recognition · Computer Science 2020-05-13 Xiangdong Zhang , Tengjun Wang , Yun Yang

Deep learning models have been widely used for anomaly detection in surveillance videos. Typical models are equipped with the capability to reconstruct normal videos and evaluate the reconstruction errors on anomalous videos to indicate the…

Computer Vision and Pattern Recognition · Computer Science 2022-11-08 Xianlin Zeng , Yalong Jiang , Wenrui Ding , Hongguang Li , Yafeng Hao , Zifeng Qiu

Computer Vision has proven to be a powerful tool for analyzing Spatial Transcriptomics (ST) data. However, current models that predict spatially resolved gene expression from histopathology images suffer from significant limitations due to…

Computer Vision and Pattern Recognition · Computer Science 2025-09-03 Paula Cárdenas , Leonardo Manrique , Daniela Vega , Daniela Ruiz , Pablo Arbeláez

Histology imaging is an essential diagnosis method to finalize the grade and stage of cancer of different tissues, especially for breast cancer diagnosis. Specialists often disagree on the final diagnosis on biopsy tissue due to the complex…

Computer Vision and Pattern Recognition · Computer Science 2019-09-17 Yongxiang Huang , Albert Chi-shing Chung