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The rapid growth of digital pathology and advances in self-supervised deep learning have enabled the development of foundational models for various pathology tasks across diverse diseases. While multimodal approaches integrating diverse…

Computer Vision and Pattern Recognition · Computer Science 2025-10-15 Ekaterina Redekop , Mara Pleasure , Zichen Wang , Kimberly Flores , Anthony Sisk , William Speier , Corey W. Arnold

Spatial transcriptomics (ST) is an emerging technology that enables researchers to investigate the molecular relationships underlying tissue morphology. However, acquiring ST data remains prohibitively expensive, and traditional fixed-grid…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Junchao Zhu , Ruining Deng , Junlin Guo , Tianyuan Yao , Chongyu Qu , Juming Xiong , Siqi Lu , Zhengyi Lu , Yanfan Zhu , Marilyn Lionts , Yuechen Yang , Yalin Zheng , Yu Wang , Shilin Zhao , Haichun Yang , Yuankai Huo

Spatial transcriptomic (ST) clustering employs spatial and transcription information to group spots spatially coherent and transcriptionally similar together into the same spatial domain. Graph convolution network (GCN) and graph attention…

Quantitative Methods · Quantitative Biology 2023-10-24 Chen Zhang , Junhui Gao , Lingxin Kong , Guangshuo cao , Xiangyu Guo , Wei Liu

Spatial transcriptomics enables gene expression profiling with spatial context, offering unprecedented insights into the tissue microenvironment. However, most computational models treat genes as isolated numerical features, ignoring the…

Machine Learning · Computer Science 2025-11-17 Jiangkai Long , Yanran Zhu , Chang Tang , Kun Sun , Yuanyuan Liu , Xuesong Yan

Spatial transcriptomics studies are becoming increasingly large and commonplace, necessitating simultaneous analysis of a large number of spatially resolved variables. Correspondingly, a diverse range of methodologies have been proposed to…

Quantitative Methods · Quantitative Biology 2025-09-09 James Boyle , Gregory Hamm , Eleanor Williams , Robin JG Hartman , Magnus Soderburg , Ian Henry , Michael Casey

Hyperspectral imaging provides precise classification for land use and cover due to its exceptional spectral resolution. However, the challenges of high dimensionality and limited spatial resolution hinder its effectiveness. This study…

Computer Vision and Pattern Recognition · Computer Science 2024-03-05 Shivam Pande

Hyperbolic spaces allow for more efficient modeling of complex, hierarchical structures, which is particularly beneficial in tasks involving multi-modal data. Although hyperbolic geometries have been proven effective for language-image…

Computer Vision and Pattern Recognition · Computer Science 2025-01-08 Yingjie Liu , Pengyu Zhang , Ziyao He , Mingsong Chen , Xuan Tang , Xian Wei

Scene graph representations enable structured visual understanding by modeling objects and their relationships, and have been widely used for multiview and 3D scene reasoning. Existing methods such as MSG learn scene graph embeddings in…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Liyang Wang , Zeyu Zhang , Hao Tang

Fine-tuning pre-trained Vision Transformers (ViTs) has showcased significant promise in enhancing visual recognition tasks. Yet, the demand for individualized and comprehensive fine-tuning processes for each task entails substantial…

Computer Vision and Pattern Recognition · Computer Science 2024-05-16 Weifeng Lin , Ziheng Wu , Wentao Yang , Mingxin Huang , Jun Huang , Lianwen Jin

The non-Euclidean geometry of hyperbolic spaces has recently garnered considerable attention in the realm of representation learning. Current endeavors in hyperbolic representation largely presuppose that the underlying hierarchies can be…

Machine Learning · Computer Science 2023-06-16 Menglin Yang , Min Zhou , Rex Ying , Yankai Chen , Irwin King

Spatial Transcriptomics (ST) offers spatially resolved gene expression but remains costly. Predicting expression directly from widely available Hematoxylin and Eosin (H&E) stained images presents a cost-effective alternative. However, most…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Jiarui Ouyang , Yihui Wang , Yihang Gao , Yingxue Xu , Shu Yang , Hao Chen

Among various region embedding methods, graph-based region relation learning models stand out, owing to their strong structure representation ability for encoding spatial correlations with graph neural networks. Despite their effectiveness,…

Machine Learning · Computer Science 2023-05-09 Qianru Zhang , Chao Huang , Lianghao Xia , Zheng Wang , Zhonghang Li , Siuming Yiu

Spatial transcriptomics (ST) measures gene expression at a set of spatial locations in a tissue. Communities of nearby cells that express similar genes form \textit{spatial domains}. Specialized ST clustering algorithms have been developed…

Quantitative Methods · Quantitative Biology 2025-11-12 Perry Beamer , Zixuan Cang

Hyperspectral image (HSI) denoising is a crucial preprocessing procedure for the subsequent HSI applications. Unfortunately, though witnessing the development of deep learning in HSI denoising area, existing convolution-based methods face…

Computer Vision and Pattern Recognition · Computer Science 2022-11-28 Miaoyu Li , Ying Fu , Yulun Zhang

We present HyperNST; a neural style transfer (NST) technique for the artistic stylization of images, based on Hyper-networks and the StyleGAN2 architecture. Our contribution is a novel method for inducing style transfer parameterized by a…

Computer Vision and Pattern Recognition · Computer Science 2022-08-10 Dan Ruta , Andrew Gilbert , Saeid Motiian , Baldo Faieta , Zhe Lin , John Collomosse

The rapid development of spatial transcriptomics (ST) technologies is revolutionizing our understanding of the spatial organization of biological tissues. Current ST methods, categorized into next-generation sequencing-based (seq-based) and…

Machine Learning · Computer Science 2024-07-19 Xiaoyu Li , Fangfang Zhu , Wenwen Min

A scalable and robust 3D tissue transcriptomics profile can enable a holistic understanding of tissue organization and provide deeper insights into human biology and disease. Most predictive algorithms that infer ST directly from histology…

Spatial Transcriptomics (ST) provides spatially-resolved gene expression, offering crucial insights into tissue architecture and complex diseases. However, its prohibitive cost limits widespread adoption, leading to significant attention on…

Computer Vision and Pattern Recognition · Computer Science 2026-03-27 Taejin Jeong , Joohyeok Kim , Jinyeong Kim , Chanyoung Kim , Seong Jae Hwang

Deep neural networks face several challenges in hyperspectral image classification, including high-dimensional data, sparse distribution of ground objects, and spectral redundancy, which often lead to classification overfitting and limited…

Computer Vision and Pattern Recognition · Computer Science 2025-06-12 Guandong Li , Mengxia Ye

Recent progress in Sign Language Translation (SLT) has focussed primarily on improving the representational capacity of large language models to incorporate Sign Language features. This work explores an alternative direction: enhancing the…

Computer Vision and Pattern Recognition · Computer Science 2025-10-29 Edward Fish , Richard Bowden
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