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Long-term monitoring of patients with epilepsy presents a challenging problem from the engineering perspective of real-time detection and wearable devices design. It requires new solutions that allow continuous unobstructed monitoring and…

Machine Learning · Computer Science 2022-04-11 Una Pale , Tomas Teijeiro , David Atienza

We apply sonification strategies and quantum computing to the analysis of an episode of seizure. We first sonify the signal from a selection of channels (from real ECoG data), obtaining a polyphonic sequence. Then, we propose two quantum…

Repeated epileptic seizures impair around 65 million people worldwide and a successful prediction of seizures could significantly help patients suffering from refractory epilepsy. For two dogs with yearlong intracranial…

Neurons and Cognition · Quantitative Biology 2022-01-13 Hongliu Yang , Matthias Eberlein , Jens Müller , Ronald Tetzlaff

Epileptic seizures are one of the most crucial neurological disorders, and their early diagnosis will help the clinicians to provide accurate treatment for the patients. The electroencephalogram (EEG) signals are widely used for epileptic…

Driven by the multi-level structure of human intracranial electroencephalogram (iEEG) recordings of epileptic seizures, we introduce a new variant of a hierarchical Dirichlet Process---the multi-level clustering hierarchical Dirichlet…

Applications · Statistics 2012-06-22 Drausin Wulsin , Shane Jensen , Brian Litt

Since the manual detection of electrographic seizures in continuous electroencephalogram (EEG) monitoring is very time-consuming and requires a trained expert, attempts to develop automatic seizure detection are diverse and ongoing. Machine…

Signal Processing · Electrical Eng. & Systems 2019-08-02 Poomipat Boonyakitanont , Apiwat Lek-uthai , Krisnachai Chomtho , Jitkomut Songsiri

Epilepsy is one of the most common neurological disorders, often requiring surgical intervention when medication fails to control seizures. For effective surgical outcomes, precise localisation of the epileptogenic focus - often…

Machine Learning · Computer Science 2024-08-28 Jamie Norris , Aswin Chari , Dorien van Blooijs , Gerald Cooray , Karl Friston , Martin Tisdall , Richard Rosch

Seizure prediction has attracted a growing attention as one of the most challenging predictive data analysis efforts in order to improve the life of patients living with drug-resistant epilepsy and tonic seizures. Many outstanding works…

Computer Vision and Pattern Recognition · Computer Science 2017-12-07 Nhan Duy Truong , Anh Duy Nguyen , Levin Kuhlmann , Mohammad Reza Bonyadi , Jiawei Yang , Omid Kavehei

This paper introduces an innovative framework designed for progressive (granular in time to onset) prediction of seizures through the utilization of a Deep Learning (DL) methodology based on non-invasive multi-modal sensor networks.…

Signal Processing · Electrical Eng. & Systems 2024-11-05 Ali Saeizadeh , Douglas Schonholtz , Joseph S. Neimat , Pedram Johari , Tommaso Melodia

Critical transitions occur in a wide variety of applications including mathematical biology, climate change, human physiology and economics. Therefore it is highly desirable to find early-warning signs. We show that it is possible to…

Dynamical Systems · Mathematics 2015-03-17 Christian Kuehn

Using an exactly solvable cortical model of a neuronal network, we show that, by increasing the intensity of shot noise (flow of random spikes bombarding neurons), the network undergoes first- and second-order non-equilibrium phase…

Biological Physics · Physics 2015-08-26 K. -E. Lee , M. A. Lopes , A. V. Goltsev

The electroencephalogram (EEG) is one of the most precious technologies to understand the happenings inside our brain and further understand our body's happenings. Automatic prediction of oncoming seizures using the EEG signals helps the…

Signal Processing · Electrical Eng. & Systems 2022-11-08 Abhijeet Bhattacharya

Developing a Brain-Computer Interface~(BCI) for seizure prediction can help epileptic patients have a better quality of life. However, there are many difficulties and challenges in developing such a system as a real-life support for…

Machine Learning · Computer Science 2017-02-20 Mohammad-Parsa Hosseini , Hamid Soltanian-Zadeh , Kost Elisevich , Dario Pompili

Epilepsy creates a persistent increase in the probability of spontaneous seizures. An ictal episode evolves due to acute disturbance of the fine-tuned balance between excitatory vs. inhibitory inputs within a neural network in favor of…

Neurons and Cognition · Quantitative Biology 2018-10-29 Eslam Abbas

Epilepsy affects millions of people, reducing quality of life and increasing risk of premature death. One-third of epilepsy cases are drug-resistant and require surgery for treatment, which necessitates localizing the seizure onset zone…

A major barrier to deploying healthcare AI models is their trustworthiness. One form of trustworthiness is a model's robustness across different subgroups: while existing models may exhibit expert-level performance on aggregate metrics,…

Machine Learning · Computer Science 2023-06-16 Khaled Saab , Siyi Tang , Mohamed Taha , Christopher Lee-Messer , Christopher Ré , Daniel Rubin

Non-ordinary states of consciousness (NOC) provide an opportunity to experience highly intense, unique, and perceptually rich subjective states. The neural mechanisms supporting these experiences remain poorly understood. This study…

Neurons and Cognition · Quantitative Biology 2025-09-24 Victor Oswald , Karim Jerbi , Corine Sombrun , Hamza Abdelhedi , Annen Jitka , Charlotte Martial , Audrey Vanhaudenhuyse , Olivia Gosseries

Epilepsy is one of the most common neurological disorders globally, affecting millions of individuals. Despite significant advancements, the precise mechanisms underlying this condition remain largely unknown, making accurately predicting…

Systems and Control · Electrical Eng. & Systems 2024-04-05 Yuzhen Qin , Ahmed El-Gazzar , Danielle S. Bassett , Fabio Pasqualetti , Marcel van Gerven

During the past two decades, epileptic seizure detection and prediction algorithms have evolved rapidly. However, despite significant performance improvements, their hardware implementation using conventional technologies, such as…

Emerging Technologies · Computer Science 2025-01-30 Chenqi Li , Corey Lammie , Xuening Dong , Amirali Amirsoleimani , Mostafa Rahimi Azghadi , Roman Genov

Seizure forecasting using machine learning is possible, but the performance is far from ideal, as indicated by many false predictions and low specificity. Here, we examine false and missing alarms of two algorithms on long-term datasets to…

Machine Learning · Computer Science 2021-10-27 Jens Müller , Hongliu Yang , Matthias Eberlein , Georg Leonhardt , Ortrud Uckermann , Levin Kuhlmann , Ronald Tetzlaff