Epilepsy affects millions of people, reducing quality of life and increasing risk of premature death. One-third of epilepsy cases are drug-resistant and require surgery for treatment, which necessitates localizing the seizure onset zone (SOZ) in the brain. Attempts have been made to use cortico-cortical evoked potentials (CCEPs) to improve SOZ localization but none have been successful enough for clinical adoption. Here, we compare the performance of ten machine learning classifiers in localizing SOZ from CCEP data. This preliminary study validates a novel application of machine learning, and the results establish our approach as a promising line of research that warrants further investigation. This work also serves to facilitate discussion and collaboration with fellow machine learning and/or epilepsy researchers.
@article{arxiv.2211.07867,
title = {Machine Learning Methods Applied to Cortico-Cortical Evoked Potentials Aid in Localizing Seizure Onset Zones},
author = {Ian G. Malone and Kaleb E. Smith and Morgan E. Urdaneta and Tyler S. Davis and Daria Nesterovich Anderson and Brian J. Phillip and John D. Rolston and Christopher R. Butson},
journal= {arXiv preprint arXiv:2211.07867},
year = {2022}
}
Comments
Extended Abstract presented at Machine Learning for Health (ML4H) symposium 2022, November 28th, 2022, New Orleans, United States & Virtual, http://www.ml4h.cc, 6 pages