Related papers: Classifying seizure generation mechanisms: A criti…
Epilepsy significantly impacts global health, affecting about 65 million people worldwide, along with various animal species. The diagnostic processes of epilepsy are often hindered by the transient and unpredictable nature of seizures.…
Re-entry of travelling excitation loops is a long-suspected driver of human seizures, yet how such loops arise in patient brain networks -- and how susceptible they are to targeted disruption -- remains unclear. We reconstruct a…
Electro-cortical activity in patients with epilepsy may show abnormal rhythmic transients in response to stimulation. Even when using the same stimulation parameters in the same patient, wide variability in the duration of transient…
Detailed analysis of seizure semiology, the symptoms and signs which occur during a seizure, is critical for management of epilepsy patients. Inter-rater reliability using qualitative visual analysis is often poor for semiological features.…
Real time seizure detection is a fundamental problem in computational neuroscience towards diagnosis and treatment's improvement of epileptic disease. We propose a real-time computational method for tracking and detection of epileptic…
In order to gain a mechanistic understanding of how tinnitus emerges in the brain, we must build biologically plausible computational models that mimic both tinnitus development and perception, and test the tentative models with brain and…
Drug-resistant epilepsy is traditionally characterized by pathologic cortical tissue comprised of seizure-initiating `foci'. These `foci' are thought to be embedded within an epileptic network whose functional architecture dynamically…
The electrical stimulation to the seizure onset zone (SOZ) serves as an efficient approach to seizure suppression. Recently, seizure dynamics have gained widespread attendance in its network propagation mechanisms. Compared with the direct…
The human brain is a directional network system of brain regions involving directional connectivity. Seizures are a directional network phenomenon as abnormal neuronal activities start from a seizure onset zone (SOZ) and propagate to…
In recent years, machine learning has become an increasingly powerful tool for supporting seizure detection and monitoring in epilepsy care. Traditional approaches focus on identifying seizures only after they begin, which limits the…
Epilepsy is a disorder of the brain denoted by frequent seizures. The symptoms of seizure include confusion, abnormal staring, and rapid, sudden, and uncontrollable hand movements. Epileptic seizure detection methods involve neurological…
Epilepsy is one of the most occurring neurological disease globally emerged back in 4000 BC. It is affecting around 50 million people of all ages these days. The trait of this disease is recurrent seizures. In the past few decades, the…
Current machine learning models aiming to predict sepsis from Electronic Health Records (EHR) do not account for the heterogeneity of the condition, despite its emerging importance in prognosis and treatment. This work demonstrates the…
Accurate prediction of epileptic seizures could prove critical for improving patient safety and quality of life in drug-resistant epilepsy. Although deep learning-based approaches have shown promising seizure prediction performance using…
Many natural and man-made systems are prone to critical transitions -- abrupt and potentially devastating changes in dynamics. Deep learning classifiers can provide an early warning signal (EWS) for critical transitions by learning generic…
Seizures are one of the defining symptoms in patients with epilepsy, and due to their unannounced occurrence, they can pose a severe risk for the individual that suffers it. New research efforts are showing a promising future for the…
Refractory epileptic patients can suffer a seizure at any moment. Seizure prediction would substantially improve their lives. In this work, based on scalp EEG and its transformation into images, the likelihood of an epileptic seizure…
The underlying dynamics for the electroencephalographic (EEG) recordings from humans but especially epilepsy patients are usually not completely known. However, the ictal activity is claimed to be characterized by synchronous oscillations…
Complex spatial connectivity patterns, such as interictal suppression and ictal propagation, complicate accurate drug-resistant epilepsy (DRE) seizure detection using stereotactic electroencephalography (SEEG) and traditional machine…
Over the past decade, high-frequency oscillations (HFOs) have been studied as a promising biomarker for localizing epileptogenic areas in drug-resistant patients requiring pre-surgical intervention, while exploiting intracranial…