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The integration of Artificial Intelligence (AI) into clinical research has great potential to reveal patterns that are difficult for humans to detect, creating impactful connections between inputs and clinical outcomes. However, these…

In this work, we present an extension of the genetic algorithm (GA) which exploits the supervised learning technique called active subspaces (AS) to evolve the individuals on a lower dimensional space. In many cases, GA requires in fact…

Numerical Analysis · Mathematics 2021-07-13 Nicola Demo , Marco Tezzele , Gianluigi Rozza

This paper proposes asal, a new GAN based active learning method that generates high entropy samples. Instead of directly annotating the synthetic samples, ASAL searches similar samples from the pool and includes them for training. Hence,…

Machine Learning · Computer Science 2019-12-24 Christoph Mayer , Radu Timofte

Stochastic Gradient Descent (SGD) is one of the most widely used techniques for online optimization in machine learning. In this work, we accelerate SGD by adaptively learning how to sample the most useful training examples at each time…

Machine Learning · Computer Science 2016-03-16 Guillaume Bouchard , Théo Trouillon , Julien Perez , Adrien Gaidon

Optimal subset selection is an important task that has numerous algorithms designed for it and has many application areas. STPGA contains a special genetic algorithm supplemented with a tabu memory property (that keeps track of previously…

Methodology · Statistics 2017-02-28 Deniz Akdemir

Self-supervised graph representation learning (SSGRL) is a representation learning paradigm used to reduce or avoid manual labeling. An essential part of SSGRL is graph data augmentation. Existing methods usually rely on heuristics commonly…

Machine Learning · Computer Science 2024-12-25 Ahmed E. Samy , Zekarias T. Kefatoa , Sarunas Girdzijauskasa

Deep generative models parameterized by neural networks have recently achieved state-of-the-art performance in unsupervised and semi-supervised learning. We extend deep generative models with auxiliary variables which improves the…

Machine Learning · Statistics 2016-06-17 Lars Maaløe , Casper Kaae Sønderby , Søren Kaae Sønderby , Ole Winther

Imitation learning demonstrates remarkable performance in various domains. However, imitation learning is also constrained by many prerequisites. The research community has done intensive research to alleviate these constraints, such as…

Neural and Evolutionary Computing · Computer Science 2023-01-19 Boyuan Zheng , Jianlong Zhou , Fang Chen

The rapid advancement of spatial transcriptomics (ST), i.e., spatial gene expressions, has made it possible to measure gene expression within original tissue, enabling us to discover molecular mechanisms. However, current ST platforms…

Computer Vision and Pattern Recognition · Computer Science 2025-11-11 Xiaofei Wang , Stephen Price , Chao Li

Spatial transcriptomics (ST) has revolutionized biomedical research by enabling high resolution gene expression profiling within tissues. However, the high cost and scarcity of high resolution ST data remain significant challenges. We…

Computer Vision and Pattern Recognition · Computer Science 2025-07-24 Yaoyu Fang , Jiahe Qian , Xinkun Wang , Lee A. Cooper , Bo Zhou

Automated scientific discovery aims to improve scientific understanding through machine learning. A central approach in this field is symbolic regression, which uses genetic programming or sparse regression to learn interpretable…

Neural and Evolutionary Computing · Computer Science 2026-03-11 Sigur de Vries , Sander W. Keemink , Marcel A. J. van Gerven

We introduce a novel training principle for probabilistic models that is an alternative to maximum likelihood. The proposed Generative Stochastic Networks (GSN) framework is based on learning the transition operator of a Markov chain whose…

Machine Learning · Computer Science 2015-03-29 Guillaume Alain , Yoshua Bengio , Li Yao , Jason Yosinski , Eric Thibodeau-Laufer , Saizheng Zhang , Pascal Vincent

Global expression analyses using microarray technologies are becoming more common in genomic research, therefore, new statistical challenges associated with combining information from multiple studies must be addressed. In this paper we…

Applications · Statistics 2013-01-29 Jia Li , George C. Tseng

Supervised learning, characterized by both discriminative and generative learning, seeks to predict the values of single (or sometimes multiple) predefined target attributes based on a predefined set of predictor attributes. For…

Machine Learning · Computer Science 2020-11-13 Yuan Jin , Wray Buntine , Francois Petitjean , Geoffrey I. Webb

Recently, large-scale language-image generative models have gained widespread attention and many works have utilized generated data from these models to further enhance the performance of perception tasks. However, not all generated data…

Computer Vision and Pattern Recognition · Computer Science 2024-06-05 Muzhi Zhu , Chengxiang Fan , Hao Chen , Yang Liu , Weian Mao , Xiaogang Xu , Chunhua Shen

Deep neural networks (DNN) have been used successfully in many scientific problems for their high prediction accuracy, but their application to genetic studies remains challenging due to their poor interpretability. In this paper, we…

Machine Learning · Computer Science 2021-10-01 Peyman H. Kassani , Fred Lu , Yann Le Guen , Zihuai He

Medical anomaly detection is a critical research area aimed at recognizing abnormal images to aid in diagnosis.Most existing methods adopt synthetic anomalies and image restoration on normal samples to detect anomaly. The unlabeled data…

Image and Video Processing · Electrical Eng. & Systems 2024-05-22 Zerui Zhang , Zhichao Sun , Zelong Liu , Bo Du , Rui Yu , Zhou Zhao , Yongchao Xu

Spatio-temporal (ST) data for urban applications, such as taxi demand, traffic flow, regional rainfall is inherently stochastic and unpredictable. Recently, deep learning based ST prediction models are proposed to learn the ST…

Machine Learning · Computer Science 2021-06-01 Divya Saxena , Jiannong Cao

Multi-task learning (MTL) can improve the generalization performance of neural networks by sharing representations with related tasks. Nonetheless, MTL can also degrade performance through harmful interference between tasks. Recent work has…

Machine Learning · Computer Science 2023-06-08 Emilie Grégoire , Hafeez Chaudhary , Sam Verboven

Spatial transcriptomics enables gene expression profiling with spatial context, offering unprecedented insights into the tissue microenvironment. However, most computational models treat genes as isolated numerical features, ignoring the…

Machine Learning · Computer Science 2025-11-17 Jiangkai Long , Yanran Zhu , Chang Tang , Kun Sun , Yuanyuan Liu , Xuesong Yan