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Integrating histopathology with spatial transcriptomics (ST) provides a powerful opportunity to link tissue morphology with molecular function. Yet most existing multimodal approaches rely on a small set of highly variable genes, which…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Sejuti Majumder , Saarthak Kapse , Moinak Bhattacharya , Xuan Xu , Alisa Yurovsky , Prateek Prasanna

Unsupervised representation learning has significantly advanced various machine learning tasks. In the computer vision domain, state-of-the-art approaches utilize transformations like random crop and color jitter to achieve invariant…

Computer Vision and Pattern Recognition · Computer Science 2025-01-16 Jaemyung Yu , Jaehyun Choi , Dong-Jae Lee , HyeongGwon Hong , Junmo Kim

Recent advances in Generative Adversarial Networks (GANs) have led to their widespread adoption for the purposes of generating high quality synthetic imagery. While capable of generating photo-realistic images, these models often produce…

Computer Vision and Pattern Recognition · Computer Science 2020-10-26 Terrance DeVries , Michal Drozdzal , Graham W. Taylor

Predicting protein secondary structure is a fundamental problem in protein structure prediction. Here we present a new supervised generative stochastic network (GSN) based method to predict local secondary structure with deep hierarchical…

Quantitative Methods · Quantitative Biology 2014-03-07 Jian Zhou , Olga G. Troyanskaya

Generalized Zero-shot Learning (GZSL) has yielded remarkable performance by designing a series of unbiased visual-semantics mappings, wherein, the precision relies heavily on the completeness of extracted visual features from both seen and…

Computer Vision and Pattern Recognition · Computer Science 2023-12-05 Zhijie Rao , Jingcai Guo , Xiaocheng Lu , Qihua Zhou , Jie Zhang , Kang Wei , Chenxin Li , Song Guo

Spatial Transcriptomics (ST) enables the measurement of gene expression while preserving spatial information, offering critical insights into tissue architecture and disease pathology. Recent developments have explored the use of…

Computer Vision and Pattern Recognition · Computer Science 2026-05-20 Hai Dang Nguyen , Nguyen Dang Huy Pham , The Minh Duc Nguyen , Dac Thai Nguyen , Hang Thi Nguyen , Duong M. Nguyen

Automated Short Answer Scoring (ASAS) is a critical component in educational assessment. While traditional ASAS systems relied on rule-based algorithms or complex deep learning methods, recent advancements in Generative Language Models…

Computation and Language · Computer Science 2024-08-08 Zifan Wang , Christopher Ormerod

Recent years have witnessed remarkable progress in multimodal learning within computational pathology. Existing models primarily rely on vision and language modalities; however, language alone lacks molecular specificity and offers limited…

Computer Vision and Pattern Recognition · Computer Science 2026-02-17 Minghao Han , Dingkang Yang , Linhao Qu , Zizhi Chen , Gang Li , Han Wang , Jiacong Wang , Lihua Zhang

In the genomic era, the identification of gene signatures associated with disease is of significant interest. Such signatures are often used to predict clinical outcomes in new patients and aid clinical decision-making. However, recent…

Methodology · Statistics 2019-03-27 Naim U. Rashid , Quefeng Li , Jen Jen Yeh , Joseph G. Ibrahim

Despite the recent progress in speech emotion recognition (SER), state-of-the-art systems lack generalisation across different conditions. A key underlying reason for poor generalisation is the scarcity of emotion datasets, which is a…

Sound · Computer Science 2022-07-13 Siddique Latif , Rajib Rana , Sara Khalifa , Raja Jurdak , Björn W. Schuller

A framework previously introduced in [3] for solving a sequence of stochastic optimization problems with bounded changes in the minimizers is extended and applied to machine learning problems such as regression and classification. The…

Machine Learning · Computer Science 2019-04-08 Craig Wilson , Yuheng Bu , Venugopal Veeravalli

A recent technology breakthrough in spatial molecular profiling has enabled the comprehensive molecular characterizations of single cells while preserving spatial information. It provides new opportunities to delineate how cells from…

Applications · Statistics 2021-10-07 Xi Jiang , Qiwei Li , Guanghua Xiao

In this paper, we propose a novel adaptive technique that uses an attention-based gated scaling (AGS) scheme to improve deep feature learning for connectionist temporal classification (CTC) acoustic modeling. In AGS, the outputs of each…

Audio and Speech Processing · Electrical Eng. & Systems 2020-01-01 Fenglin Ding , Wu Guo , Lirong Dai , Jun Du

It has been widely recognized that the success of deep learning in image segmentation relies overwhelmingly on a myriad amount of densely annotated training data, which, however, are difficult to obtain due to the tremendous labor and…

Computer Vision and Pattern Recognition · Computer Science 2020-11-26 Yutong Xie , Jianpeng Zhang , Zehui Liao , Yong Xia , Chunhua Shen

Spatial transcriptomics technologies enable the measurement of gene expression with spatial context, providing opportunities to understand how gene regulatory networks vary across tissue regions. However, existing graphical models focus…

Methodology · Statistics 2025-12-15 Trisha Dawn , Yang Ni

Recent advancements in spatial transcriptomics technologies allow researchers to simultaneously measure RNA expression levels for hundreds to thousands of genes while preserving spatial information within tissues, providing critical…

Methodology · Statistics 2025-07-31 Catherine Higgins , Jingyi Jessica Li , Michelle Carey

Spatial transcriptomics provides an unprecedented perspective for deciphering tissue spatial heterogeneity. However, high-resolution spatial transcriptomic technology remains constrained by limited gene coverage, technical complexity, and…

Biomolecules · Quantitative Biology 2026-05-19 Xinlei Huang , Weihao Dai , Zijun Qin , Xin Yu , Di Wang , Yanran Liu , Lixin Cheng , Xubin Zheng

The technology to generate Spatially Resolved Transcriptomics (SRT) data is rapidly being improved and applied to investigate a variety of biological tissues. The ability to interrogate how spatially localised gene expression can lend new…

Quantitative Methods · Quantitative Biology 2021-08-04 Natalie Charitakis , Mirana Ramialison , Hieu T. Nim

We consider the problem of data augmentation, i.e., generating artificial samples to extend a given corpus of training data. Specifically, we propose attributed-guided augmentation (AGA) which learns a mapping that allows to synthesize data…

Computer Vision and Pattern Recognition · Computer Science 2017-08-29 Mandar Dixit , Roland Kwitt , Marc Niethammer , Nuno Vasconcelos

The integration of Generative AI (GenAI) into education is reshaping how students learn, making self-regulated learning (SRL) - the ability to plan, monitor, and adapt one's learning - more important than ever. To support learners in these…

Human-Computer Interaction · Computer Science 2025-08-15 Kaixun Yang , Yizhou Fan , Luzhen Tang , Mladen Raković , Xinyu Li , Dragan Gašević , Guanliang Chen
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