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Representation learning is a key technique in modern machine learning that enables models to identify meaningful patterns in complex data. However, different methods tend to extract distinct aspects of the data, and relying on a single…

Machine Learning · Statistics 2025-09-30 Wenhui Li , Shijin Gong , Xinyu Zhang

Cellular identity and function are linked to both their intrinsic genomic makeup and extrinsic spatial context within the tissue microenvironment. Spatial transcriptomics (ST) offers an unprecedented opportunity to study this, providing in…

Machine Learning · Computer Science 2026-02-16 Rui Yan , Xiaohan Xing , Xun Wang , Zixia Zhou , Md Tauhidul Islam , Lei Xing

In several supervised learning scenarios, auxiliary losses are used in order to introduce additional information or constraints into the supervised learning objective. For instance, knowledge distillation aims to mimic outputs of a powerful…

Machine Learning · Computer Science 2022-12-08 Durga Sivasubramanian , Ayush Maheshwari , Pradeep Shenoy , Prathosh AP , Ganesh Ramakrishnan

Temporal sentence grounding (TSG) is crucial and fundamental for video understanding. Although the existing methods train well-designed deep networks with a large amount of data, we find that they can easily forget the rarely appeared cases…

Computer Vision and Pattern Recognition · Computer Science 2022-01-04 Daizong Liu , Xiaoye Qu , Xing Di , Yu Cheng , Zichuan Xu , Pan Zhou

Spatial transcriptomics (ST) technologies have revolutionized the study of gene expression patterns in tissues by providing multimodality data in transcriptomic, spatial, and morphological, offering opportunities for understanding tissue…

Computational Engineering, Finance, and Science · Computer Science 2024-01-17 Zelin Zang , Liangyu Li , Yongjie Xu , Chenrui Duan , Kai Wang , Yang You , Yi Sun , Stan Z. Li

Spatial transcriptomics (ST) profiles gene expression across a tissue section while preserving the spatial coordinates. Because current ST technologies typically profile two-dimensional tissue slices, integrating and aligning slices from…

Quantitative Methods · Quantitative Biology 2026-03-20 Yaqi Wu , Jingfeng Wang , Xin Maizie Zhou , Yanxiang Zhao , Zixuan Cang

Transfer learning from high-resource languages is known to be an efficient way to improve end-to-end automatic speech recognition (ASR) for low-resource languages. Pre-trained or jointly trained encoder-decoder models, however, do not share…

Audio and Speech Processing · Electrical Eng. & Systems 2020-10-12 Changhan Wang , Juan Pino , Jiatao Gu

Active learning selects the most informative samples to exploit limited annotation budgets. Existing work follows a cumbersome pipeline that repeats the time-consuming model training and batch data selection multiple times. In this paper,…

Computer Vision and Pattern Recognition · Computer Science 2022-03-22 Yichen Xie , Masayoshi Tomizuka , Wei Zhan

Recently, the introduction of the generative adversarial network (GAN) and its variants has enabled the generation of realistic synthetic samples, which has been used for enlarging training sets. Previous work primarily focused on data…

Machine Learning · Computer Science 2018-08-27 Swee Kiat Lim , Yi Loo , Ngoc-Trung Tran , Ngai-Man Cheung , Gemma Roig , Yuval Elovici

Transcriptomic analysis are characterized by being not directly quantitative and only providing relative measurements of expression levels up to an unknown individual scaling factor. This difficulty is enhanced for differential expression…

Methodology · Statistics 2021-03-24 Dorota Desaulle , Céline Hoffmann , Bernard Hainque , Yves Rozenholc

Gene expression profiling technologies have been used in various applications such as cancer biology. The development of gene expression profiling has expanded the scope of target discovery in transcriptomic studies, and each technology…

Genomics · Quantitative Biology 2023-01-10 Hyeongseon Jeon , Juan Xie , Yeseul Jeon , Kyeong Joo Jung , Arkobrato Gupta , Won Chang , Dongjun Chung

Triggered by the success of transformers in various visual tasks, the spatial self-attention mechanism has recently attracted more and more attention in the computer vision community. However, we empirically found that a typical vision…

Computer Vision and Pattern Recognition · Computer Science 2022-11-28 Jiayin Sun , Hong Wang , Qiulei Dong

We propose a nonparametric procedure to achieve fast inference in generative graphical models when the number of latent states is very large. The approach is based on iterative latent variable preselection, where we alternate between…

Machine Learning · Statistics 2021-10-06 Jacquelyn A. Shelton , Jan Gasthaus , Zhenwen Dai , Joerg Luecke , Arthur Gretton

Assembly state recognition facilitates the execution of assembly procedures, offering feedback to enhance efficiency and minimize errors. However, recognizing assembly states poses challenges in scalability, since parts are frequently…

Computer Vision and Pattern Recognition · Computer Science 2025-10-15 Tim J. Schoonbeek , Goutham Balachandran , Hans Onvlee , Tim Houben , Shao-Hsuan Hung , Jacek Kustra , Peter H. N. de With , Fons van der Sommen

Large language models (LLMs) can memorize and reproduce training sequences verbatim -- a tendency that undermines both generalization and privacy. Existing mitigation methods apply interventions uniformly, degrading performance on the…

Machine Learning · Computer Science 2026-02-10 Xuanqi Zhang , Haoyang Shang , Xiaoxiao Li

Anomaly detection plays a crucial role in various real-world applications, including healthcare and finance systems. Owing to the limited number of anomaly labels in these complex systems, unsupervised anomaly detection methods have…

Machine Learning · Computer Science 2023-10-10 Zongyuan Huang , Baohua Zhang , Guoqiang Hu , Longyuan Li , Yanyan Xu , Yaohui Jin

Symbolic regression is a technique that can automatically derive analytic models from data. Traditionally, symbolic regression has been implemented primarily through genetic programming that evolves populations of candidate solutions…

Neural and Evolutionary Computing · Computer Science 2025-04-24 Jiří Kubalík , Robert Babuška

In training speech recognition systems, labeling audio clips can be expensive, and not all data is equally valuable. Active learning aims to label only the most informative samples to reduce cost. For speech recognition, confidence scores…

Computation and Language · Computer Science 2016-12-13 Jiaji Huang , Rewon Child , Vinay Rao , Hairong Liu , Sanjeev Satheesh , Adam Coates

Standard deep learning relies on Backpropagation (BP), which is constrained by biologically implausible weight symmetry and suffers from significant gradient interference within dense representations. To mitigate these bottlenecks, we…

Machine Learning · Computer Science 2026-01-30 Fanping Liu , Hua Yang , Jiasi Zou

Spatial transcriptomics (ST) measures gene expression at fine-grained spatial resolution, offering insights into tissue molecular landscapes. Previous methods for spatial gene expression prediction typically crop spots of interest from…

Computer Vision and Pattern Recognition · Computer Science 2025-11-26 Ruikun Zhang , Yan Yang , Liyuan Pan