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Survival analysis plays a vital role in making clinical decisions. However, the models currently in use are often difficult to interpret, which reduces their usefulness in clinical settings. Prototype learning presents a potential solution,…

Computer Vision and Pattern Recognition · Computer Science 2025-10-08 Shuo Jiang , Zhuwen Chen , Liaoman Xu , Yanming Zhu , Changmiao Wang , Jiong Zhang , Feiwei Qin , Yifei Chen , Zhu Zhu

Artificial intelligence has advanced in Medical Visual Question Answering (Med-VQA), but prevalent research tends to focus on the accuracy of the answers, often overlooking the reasoning paths and interpretability, which are crucial in…

Computer Vision and Pattern Recognition · Computer Science 2024-12-19 Jiaxiang Liu , Yuan Wang , Jiawei Du , Joey Tianyi Zhou , Zuozhu Liu

Multimodal pathology-genomic analysis is critical for cancer survival prediction. However, existing approaches predominantly integrate formalin-fixed paraffin-embedded (FFPE) slides with genomic data, while neglecting the availability of…

Computer Vision and Pattern Recognition · Computer Science 2025-06-25 Mingcheng Qu , Guang Yang , Donglin Di , Yue Gao , Tonghua Su , Yang Song , Lei Fan

Histo-genomic multimodal survival prediction has garnered growing attention for its remarkable model performance and potential contributions to precision medicine. However, a significant challenge in clinical practice arises when only…

Machine Learning · Computer Science 2025-03-17 Fengchun Liu , Linghan Cai , Zhikang Wang , Zhiyuan Fan , Jin-gang Yu , Hao Chen , Yongbing Zhang

We introduce ProtoPathway, an interpretable-by-design multimodal framework for cancer survival prediction that unifies whole slide imaging and transcriptomics through encoders producing biologically grounded representations on both sides of…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Amaya Gallagher-Syed , Costantino Pitzalis , Myles J. Lewis , Michael R. Barnes , Gregory Slabaugh

Large Language Model (LLM) based multi-agent systems (MAS) have shown promise in tackling complex tasks, but often rely on predefined roles and centralized coordination, limiting their adaptability to evolving challenges. This paper…

Artificial Intelligence · Computer Science 2025-09-04 Siyuan Lu , Jiaqi Shao , Bing Luo , Tao Lin

Currently, there is a noticeable lack of AI in the medical field to support doctors in treating heterogenous brain tumors such as Glioblastoma Multiforme (GBM), the deadliest human cancer in the world with a five-year survival rate of just…

Artificial Intelligence · Computer Science 2025-12-09 Krishna Arun , Moinak Bhattachrya , Paras Goel

Housing selection is a high-stakes and largely irreversible decision problem. We study housing consultation as a decision-support interface for housing selection. Existing housing platforms and many LLM-based assistants often reduce this…

Machine Learning · Computer Science 2026-04-02 Hongyang Yang , Yanxin Zhang , Yang She , Yue Xiao , Hao Wu , Yiyang Zhang , Jiapeng Hou , Rongshan Zhang

We propose an experience-guided cascaded multi-agent framework for Breast Ultrasound Screening and Diagnosis, called BUSD-Agent, that aims to reduce diagnostic escalation and unnecessary biopsy referrals. Our framework models screening and…

Computer Vision and Pattern Recognition · Computer Science 2026-03-02 Pramit Saha , Mohammad Alsharid , Joshua Strong , J. Alison Noble

Computer-aided cancer survival risk prediction plays an important role in the timely treatment of patients. This is a challenging weakly supervised ordinal regression task associated with multiple clinical factors involved such as…

Machine Learning · Computer Science 2024-09-05 Zekang Yang , Hong Liu , Xiangdong Wang

Cancer survival prediction from multi-omics data remains challenging because prognostic signals are high-dimensional, heterogeneous, and distributed across interacting genes and pathways. We propose PathMoG, a pathway-centric modular graph…

Machine Learning · Computer Science 2026-04-28 Di Wang , Chupei Tang , Junxiao Kong , Jixiu Zhai , Moyu Tang , Tianchi Lu

When oncologists estimate cancer patient survival, they rely on multimodal data. Even though some multimodal deep learning methods have been proposed in the literature, the majority rely on having two or more independent networks that share…

Image and Video Processing · Electrical Eng. & Systems 2022-09-13 Numan Saeed , Ikboljon Sobirov , Roba Al Majzoub , Mohammad Yaqub

Endoscopic diagnosis is an iterative process in which clinicians progressively acquire, compare, and verify local visual evidence before reaching a conclusion. Current AI systems do not adequately support this process because fine-grained…

Artificial Intelligence · Computer Science 2026-05-19 Yi Tang , Kai-Ni Wang , Yang Chen , Xiaopu He , Guangquan Zhou

Training and evaluating autonomous driving algorithms requires a diverse range of scenarios. However, most available datasets predominantly consist of normal driving behaviors demonstrated by human drivers, resulting in a limited number of…

Robotics · Computer Science 2025-05-27 Miao Li , Wenhao Ding , Haohong Lin , Yiqi Lyu , Yihang Yao , Yuyou Zhang , Ding Zhao

Large Language Models (LLMs) and multi-agent systems have shown impressive capabilities in natural language tasks but face challenges in clinical trial applications, primarily due to limited access to external knowledge. Recognizing the…

Computation and Language · Computer Science 2024-07-23 Ling Yue , Sixue Xing , Jintai Chen , Tianfan Fu

A fundamental aspect of behaviour is the ability to encode salient features of experience in memory and use these memories, in combination with current sensory information, to predict the best action for each situation such that long-term…

Neural and Evolutionary Computing · Computer Science 2021-06-25 Stephen Kelly , Tatiana Voegerl , Wolfgang Banzhaf , Cedric Gondro

Accurate and interpretable survival analysis remains a core challenge in oncology. With growing multimodal data and the clinical need for transparent models to support validation and trust, this challenge increases in complexity. We propose…

Artificial Intelligence · Computer Science 2025-09-29 Mafalda Malafaia , Peter A. N. Bosman , Coen Rasch , Tanja Alderliesten

Although text recognition has significantly evolved over the years, state-of-the-art (SOTA) models still struggle in the wild scenarios due to complex backgrounds, varying fonts, uncontrolled illuminations, distortions and other artefacts.…

Computer Vision and Pattern Recognition · Computer Science 2021-07-28 Ayan Kumar Bhunia , Aneeshan Sain , Amandeep Kumar , Shuvozit Ghose , Pinaki Nath Chowdhury , Yi-Zhe Song

Recent multimodal LLMs have shown promise in chart-based visual question answering, but their performance declines sharply on unannotated charts-those requiring precise visual interpretation rather than relying on textual shortcuts. To…

Artificial Intelligence · Computer Science 2026-01-08 Rachneet Kaur , Nishan Srishankar , Zhen Zeng , Sumitra Ganesh , Manuela Veloso

Agent-based modeling is indispensable for studying complex systems across many domains. However, existing simulation platforms exhibit two major issues: performance and modularity. Low performance prevents simulations with a large number of…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-03-17 Lukas Johannes Breitwieser