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Multidisciplinary team (MDT) consultations are the gold standard for cancer care decision-making, yet current practice lacks structured mechanisms for quantifying consensus and ensuring decision traceability. We introduce a Multi-Agent…

Multiagent Systems · Computer Science 2025-12-17 Xudong Han , Xianglun Gao , Xiaoyi Qu , Zhenyu Yu

Precision therapeutics require multimodal adaptive models that generate personalized treatment recommendations. We introduce TxAgent, an AI agent that leverages multi-step reasoning and real-time biomedical knowledge retrieval across a…

Artificial Intelligence · Computer Science 2025-03-17 Shanghua Gao , Richard Zhu , Zhenglun Kong , Ayush Noori , Xiaorui Su , Curtis Ginder , Theodoros Tsiligkaridis , Marinka Zitnik

Breast ultrasound diagnosis typically proceeds from global lesion localization to local sign assessment and then evidence integration to assign a BI-RADS category and determine benignity or malignancy. Many existing methods rely on…

Computer Vision and Pattern Recognition · Computer Science 2026-03-12 Yali Zhu , Kang Zhou , Dingbang Wu , Gaofeng Meng

Two challenging problems in the clinical study of cancer are the characterization of cancer subtypes and the classification of individual patients according to those subtypes. Statistical approaches addressing these problems are hampered by…

Methodology · Statistics 2012-02-28 John A. Dawson , Christina Kendziorski

Causal inference holds immense value in fields such as healthcare, economics, and social sciences. However, traditional causal analysis workflows impose significant technical barriers, requiring researchers to possess dual backgrounds in…

Artificial Intelligence · Computer Science 2026-02-13 Jiawei Zhu , Wei Chen , Ruichu Cai

Recent advances in large language models have enabled AI systems to achieve expert-level performance on domain-specific scientific tasks, yet these systems remain narrow and handcrafted. We introduce SciAgent, a unified multi-agent system…

Multimodal neuroimaging analysis often involves complex, modality-specific preprocessing workflows that require careful configuration, quality control, and coordination across heterogeneous toolchains. Beyond preprocessing, downstream…

Artificial Intelligence · Computer Science 2026-05-08 Lujia Zhong , Yihao Xia , Jianwei Zhang , Shuo huang , Jiaxin Yue , Mingyang Xia , Yonggang Shi

Survival prediction aims to evaluate the risk level of cancer patients. Existing methods primarily rely on pathology and genomics data, either individually or in combination. From the perspective of cancer pathogenesis, epigenetic changes,…

Machine Learning · Computer Science 2025-06-23 Haipeng Zhou , Sicheng Yang , Sihan Yang , Jing Qin , Lei Chen , Lei Zhu

While interpretable prototype networks offer compelling case-based reasoning for clinical diagnostics, their raw continuous outputs lack the semantic structure required for medical documentation. Bridging this gap via standard…

Computer Vision and Pattern Recognition · Computer Science 2026-05-29 Alvaro Lopez Pellicer , Plamen Angelov , Marwan Bukhari , Yi Li , Eduardo Soares , Jemma Kerns

Artificial intelligence has shown promise in medical imaging, yet most existing systems lack flexibility, interpretability, and adaptability - challenges especially pronounced in ophthalmology, where diverse imaging modalities are…

Diagnosing a whole-slide image is an interactive, multi-stage process of changing magnification and moving between fields. Although recent pathology foundation models demonstrated superior performances, practical agentic systems that decide…

Computer Vision and Pattern Recognition · Computer Science 2025-10-15 Sheng Wang , Ruiming Wu , Charles Herndon , Yihang Liu , Shunsuke Koga , Jeanne Shen , Zhi Huang

While Large Language Models (LLMs) have demonstrated potential in healthcare, they often struggle with the complex, non-linear reasoning required for accurate clinical diagnosis. Existing methods typically rely on static, linear mappings…

Computation and Language · Computer Science 2026-05-28 Zhuohan Ge , Haoyang Li , Yubo Wang , Nicole Hu , Chen Jason Zhang , Qing Li

This paper introduces DeepPsy-Agent, an innovative psychological support system that combines the three-stage helping theory in psychology with deep learning techniques. The system consists of two core components: (1) a multi-stage…

Artificial Intelligence · Computer Science 2025-03-21 Kai Chen , Zebing Sun

Time-to-event prediction, e.g. cancer survival analysis or hospital length of stay, is a highly prominent machine learning task in medical and healthcare applications. However, only a few interpretable machine learning methods comply with…

Computer Vision and Pattern Recognition · Computer Science 2024-11-25 Hubert Baniecki , Bartlomiej Sobieski , Patryk Szatkowski , Przemyslaw Bombinski , Przemyslaw Biecek

The rapid evolution of sophisticated cyberattacks has strained modern Security Operations Centers (SOC), which traditionally rely on rule-based or signature-driven detection systems. These legacy frameworks often generate high volumes of…

Cryptography and Security · Computer Science 2026-03-03 Chuanming Tang , Ling Qing , Shifeng Chen

Chimeric antigen receptor T-cell (CAR-T) therapy represents a paradigm shift in cancer treatment, yet development timelines of 8-12 years and clinical attrition rates exceeding 40-60% highlight critical inefficiencies in target selection,…

Quantitative Methods · Quantitative Biology 2025-11-13 Yi Ni , Liwei Zhu , Shuai Li

Vision-language models (VLM) have markedly advanced AI-driven interpretation and reporting of complex medical imaging, such as computed tomography (CT). Yet, existing methods largely relegate clinicians to passive observers of final…

Model fusion is a key strategy for robust recognition in unconstrained scenarios, as different models provide complementary strengths. This is especially important for whole-body human recognition, where biometric cues such as face, gait,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Jie Zhu , Xiao Guo , Yiyang Su , Anil Jain , Xiaoming Liu

Histopathology remains the gold standard for cancer diagnosis because it provides detailed cellular-level assessment of tissue morphology. However, manual histopathological examination is time-consuming, labour-intensive, and subject to…

Computer Vision and Pattern Recognition · Computer Science 2026-03-13 Ravi Mosalpuri , Mohammed Abdelsamea , Ahmed Karam Eldaly

Multimodal clinical reasoning in the field of gastrointestinal (GI) oncology necessitates the integrated interpretation of endoscopic imagery, radiological data, and biochemical markers. Despite the evident potential exhibited by Multimodal…