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Background. Subdural hematoma (SDH) is a common neurosurgical emergency, with increasing incidence in aging populations. Rapid and accurate identification is essential to guide timely intervention, yet existing automated tools focus…

Computer Vision and Pattern Recognition · Computer Science 2025-12-11 Vasiliki Stoumpou , Rohan Kumar , Bernard Burman , Diego Ojeda , Tapan Mehta , Dimitris Bertsimas

Spatial variable genes (SVGs) reveal critical information about tissue architecture, cellular interactions, and disease microenvironments. As spatial transcriptomics (ST) technologies proliferate, accurately identifying SVGs across diverse…

Applications · Statistics 2025-10-21 Jiawen Chen , Jinwei Zhang , Dongshen Peng , Yutong Song , Aitong Ruan , Yun Li , Didong Li

Whole slide images (WSIs) enable weakly supervised prognostic modeling via multiple instance learning (MIL). Spatial transcriptomics (ST) preserves in situ gene expression, providing a spatial molecular context that complements morphology.…

Computer Vision and Pattern Recognition · Computer Science 2026-02-16 Lihe Liu , Xiaoxi Pan , Yinyin Yuan , Lulu Shang

We propose a heterogeneous graph mamba network (HGMN) as the first exploration in leveraging the selective state space models (SSSMs) for heterogeneous graph learning. Compared with the literature, our HGMN overcomes two major challenges:…

Machine Learning · Computer Science 2024-05-24 Zhenyu Pan , Yoonsung Jeong , Xiaoda Liu , Han Liu

Spatial Transcriptomics (ST) profiles thousands of gene expression values at discrete spots with precise coordinates on tissue sections, preserving spatial context essential for clinical and pathological studies. With rising sequencing…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Yishun Zhu , Jiaxin Qi , Jian Wang , Yuhua Zheng , Jianqiang Huang

A high-performing, general-purpose visual understanding model should map visual inputs to a taxonomic tree of labels, identify novel categories beyond the training set for which few or no publicly available images exist. Large Multimodal…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Hulingxiao He , Zhi Tan , Yuxin Peng

In many data-driven applications, higher-order relationships among multiple objects are essential in capturing complex interactions. Hypergraphs, which generalize graphs by allowing edges to connect any number of nodes, provide a flexible…

Spatial Transcriptomics is a novel technology that aligns histology images with spatially resolved gene expression profiles. Although groundbreaking, it struggles with gene capture yielding high corruption in acquired data. Given potential…

Computer Vision and Pattern Recognition · Computer Science 2024-09-30 Gabriel Mejia , Daniela Ruiz , Paula Cárdenas , Leonardo Manrique , Daniela Vega , Pablo Arbeláez

Modern ultra-high-resolution image synthesis relies heavily on the robust generative capacity of large-scale pre-trained Latent Diffusion Models (LDMs). While recent representation alignment methods have proven effective by distilling…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Jinjin Zhang , Xiefan Guo , Di Huang

Histomorphology is crucial in cancer diagnosis. However, existing whole slide image (WSI) classification methods struggle to effectively incorporate histomorphology information, limiting their ability to capture key pathological features.…

Computer Vision and Pattern Recognition · Computer Science 2025-12-01 Baizhi Wang , Rui Yan , Wenxin Ma , Xu Zhang , Yuhao Wang , Xiaolong Li , Yunjie Gu , Zihang Jiang , S. Kevin Zhou

Spatial omics (SO) technologies enable spatially resolved molecular profiling, while hematoxylin and eosin (H&E) imaging remains the gold standard for morphological assessment in clinical pathology. Recent computational advances…

Electrocardiogram (ECG) diagnosis remains challenging due to limited labeled data and the need to capture subtle yet clinically meaningful variations in rhythm and morphology. We present CREMA (Contrastive Regularized Masked Autoencoder), a…

Machine Learning · Computer Science 2025-08-22 Junho Song , Jong-Hwan Jang , DongGyun Hong , Joon-myoung Kwon , Yong-Yeon Jo

Computational analysis of multiplexed immunofluorescence histology data is emerging as an important method for understanding the tumour micro-environment in cancer. This work presents HEMIT, a dataset designed for translating Hematoxylin…

Image and Video Processing · Electrical Eng. & Systems 2024-09-30 Chang Bian , Beth Philips , Tim Cootes , Martin Fergie

With the rapid advancement of Spatial Resolved Transcriptomics (SRT) technology, it is now possible to comprehensively measure gene transcription while preserving the spatial context of tissues. Spatial domain identification and gene…

Genomics · Quantitative Biology 2024-08-14 Donghai Fang , Fangfang Zhu , Dongting Xie , Wenwen Min

Spatially Resolved Transcriptomics (SRT) is a cutting-edge technique that captures the spatial context of cells within tissues, enabling the study of complex biological networks. Recent graph-based methods leverage both gene expression and…

Machine Learning · Computer Science 2025-06-24 Yunhak Oh , Junseok Lee , Yeongmin Kim , Sangwoo Seo , Namkyeong Lee , Chanyoung Park

Graph matching finds the correspondence of nodes across two correlated graphs and lies at the core of many applications. When graph side information is not available, the node correspondence is estimated on the sole basis of network…

Machine Learning · Computer Science 2022-02-08 Weijie Liu , Chao Zhang , Nenggan Zheng , Hui Qian

The self-supervised ultrasound (US) video model pretraining can use a small amount of labeled data to achieve one of the most promising results on US diagnosis. However, it does not take full advantage of multi-level knowledge for learning…

Computer Vision and Pattern Recognition · Computer Science 2022-10-14 Chunhui Zhang , Yixiong Chen , Li Liu , Qiong Liu , Xi Zhou

Self-supervised learning (SSL) has delivered superior performance on a variety of downstream vision tasks. Two main-stream SSL frameworks have been proposed, i.e., Instance Discrimination (ID) and Masked Image Modeling (MIM). ID pulls…

Computer Vision and Pattern Recognition · Computer Science 2022-11-17 Chenxin Tao , Xizhou Zhu , Weijie Su , Gao Huang , Bin Li , Jie Zhou , Yu Qiao , Xiaogang Wang , Jifeng Dai

Spatial Transcriptomics (ST) is a method that captures gene expression profiles aligned with spatial coordinates. The discrete spatial distribution and the super-high dimensional sequencing results make ST data challenging to be modeled…

Machine Learning · Computer Science 2025-05-08 Qingtian Zhu , Yumin Zheng , Yuling Sang , Yifan Zhan , Ziyan Zhu , Jun Ding , Yinqiang Zheng

Based on digital pathology slice scanning technology, artificial intelligence algorithms represented by deep learning have achieved remarkable results in the field of computational pathology. Compared to other medical images, pathology…

Image and Video Processing · Electrical Eng. & Systems 2023-11-17 Hao Quan , Xingyu Li , Weixing Chen , Qun Bai , Mingchen Zou , Ruijie Yang , Tingting Zheng , Ruiqun Qi , Xinghua Gao , Xiaoyu Cui