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While deep learning has significantly advanced medical image segmentation, most existing methods still struggle with handling complex anatomical regions. Cascaded or deep supervision-based approaches attempt to address this challenge…

Image and Video Processing · Electrical Eng. & Systems 2025-03-03 Tao Chen , Chenhui Wang , Zhihao Chen , Hongming Shan

Existing works of reasoning segmentation often fall short in complex cases, particularly when addressing complicated queries and out-of-domain images. Inspired by the chain-of-thought reasoning, where harder problems require longer thinking…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Shiu-hong Kao , Chak Ho Huang , Huaiqian Liu , Yu-Wing Tai , Chi-Keung Tang

Medical image segmentation plays a vital role in clinical decision-making, enabling precise localization of lesions and guiding interventions. Despite significant advances in segmentation accuracy, the black-box nature of most deep models…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Limai Jiang , Ruitao Xie , Bokai Yang , Huazhen Huang , Juan He , Yufu Huo , Zikai Wang , Yang Wei , Yunpeng Cai

Medical image grounding aims to align natural language phrases with specific regions in medical images, serving as a foundational task for intelligent diagnosis, visual question answering (VQA), and automated report generation (MRG).…

Computer Vision and Pattern Recognition · Computer Science 2025-11-07 Ziye Deng , Ruihan He , Jiaxiang Liu , Yuan Wang , Zijie Meng , Songtao Jiang , Yong Xie , Zuozhu Liu

Question answering is a natural language understanding task that involves reasoning over both explicit context, and unstated relevant domain knowledge. Despite the high cost of training, large language models (LLMs) -- the backbone of most…

Computation and Language · Computer Science 2025-04-24 Laura Cabello , Carmen Martin-Turrero , Uchenna Akujuobi , Anders Søgaard , Carlos Bobed

Process-Level Reward Models (PRMs) are essential for guiding complex reasoning in large language models, yet existing PRM benchmarks cover only general domains such as mathematics, failing to address medical reasoning -- which is uniquely…

Computation and Language · Computer Science 2026-04-21 Lingyan Wu , Xiang Zheng , Weiqi Zhai , Wei Wang , Xuan Ren , Zifan Zhang , Hu Wei , Bing Zhao

Over the past few years, the rapid development of deep learning technologies for computer vision has significantly improved the performance of medical image segmentation (MedISeg). However, the diverse implementation strategies of various…

Computer Vision and Pattern Recognition · Computer Science 2023-05-09 Dong Zhang , Yi Lin , Hao Chen , Zhuotao Tian , Xin Yang , Jinhui Tang , Kwang Ting Cheng

Incentivizing the reasoning ability of Multimodal Large Language Models (MLLMs) is essential for medical applications to transparently analyze medical scans and provide reliable diagnosis. However, existing medical MLLMs rely solely on…

Computer Vision and Pattern Recognition · Computer Science 2025-10-22 Lehan Wang , Yi Qin , Honglong Yang , Xiaomeng Li

Semantic medical image segmentation using deep learning has recently achieved high accuracy, making it appealing to clinical problems such as radiation therapy. However, the lack of high-quality semantically labelled data remains a…

Image and Video Processing · Electrical Eng. & Systems 2023-03-13 Wei Dai , Siyu Liu , Craig B. Engstrom , Shekhar S. Chandra

The prosperity of Multimodal Large Language Models (MLLMs) has stimulated the demand for video reasoning segmentation, which aims to segment video objects based on human instructions. Previous studies rely on unidirectional and implicit…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Jingnan Luo , Mingqi Gao , Jun Liu , Bin-Bin Gao , Feng Zheng

Pre-trained segmentation models are a powerful and flexible tool for segmenting images. Recently, this trend has extended to medical imaging. Yet, often these methods only produce a single prediction for a given image, neglecting inherent…

Computer Vision and Pattern Recognition · Computer Science 2025-03-14 Benjamin Towle , Xin Chen , Ke Zhou

Misdiagnosis causes significant harm to healthcare systems worldwide, leading to increased costs and patient risks. MedRAG is a smart multimodal healthcare copilot equipped with powerful large language model (LLM) reasoning, designed to…

Artificial Intelligence · Computer Science 2025-06-04 Xuejiao Zhao , Siyan Liu , Su-Yin Yang , Chunyan Miao

As Vision-Language Models (VLMs) increasingly gain traction in medical applications, clinicians are progressively expecting AI systems not only to generate textual diagnoses but also to produce corresponding medical images that integrate…

Computer Vision and Pattern Recognition · Computer Science 2025-11-19 Junjie Yang , Yuhao Yan , Gang Wu , Yuxuan Wang , Ruoyu Liang , Xinjie Jiang , Xiang Wan , Fenglei Fan , Yongquan Zhang , Feiwei Qin , Changmiao Wang

Retrieval-Augmented Generation (RAG) is widely employed to mitigate risks such as hallucinations and knowledge obsolescence in medical question answering, yet its predominantly single-round, static retrieval paradigm misaligns with the…

Computation and Language · Computer Science 2026-05-19 Yongfeng Huang , Ruiying Chen , James Cheng

Deep segmentation models often face the failure risks when the testing image presents unseen distributions. Improving model robustness against these risks is crucial for the large-scale clinical application of deep models. In this study,…

Computer Vision and Pattern Recognition · Computer Science 2022-07-04 Yuhao Huang , Xin Yang , Xiaoqiong Huang , Jiamin Liang , Xinrui Zhou , Cheng Chen , Haoran Dou , Xindi Hu , Yan Cao , Dong Ni

The COVID-19 pandemic response highlighted the potential of deep learning methods in facilitating the diagnosis, prognosis and understanding of lung diseases through automated segmentation of pulmonary structures and lesions in chest…

Image and Video Processing · Electrical Eng. & Systems 2024-03-27 Diedre S. Carmo , Jean A. Ribeiro , Alejandro P. Comellas , Joseph M. Reinhardt , Sarah E. Gerard , Letícia Rittner , Roberto A. Lotufo

Large Language Models (LLMs) exhibit high reasoning capacity in medical question-answering, but their tendency to produce hallucinations and outdated knowledge poses critical risks in healthcare fields. While Retrieval-Augmented Generation…

Computation and Language · Computer Science 2026-03-25 Wenhao Wu , Zhentao Tang , Yafu Li , Shixiong Kai , Mingxuan Yuan , Chunlin Chen , Zhi Wang

Multimodal Large Language Models (MLLMs) have shown exceptional capabilities in vision-language tasks; however, effectively integrating image segmentation into these models remains a significant challenge. In this paper, we introduce…

Computer Vision and Pattern Recognition · Computer Science 2025-02-18 Mengcheng Lan , Chaofeng Chen , Yue Zhou , Jiaxing Xu , Yiping Ke , Xinjiang Wang , Litong Feng , Wayne Zhang

Bridging clinical diagnostic reasoning with AI remains a central challenge in medical imaging. We introduce MedCLM, an automated pipeline that converts detection datasets into large-scale medical visual question answering (VQA) data with…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Soo Yong Kim , Suin Cho , Vincent-Daniel Yun , Gyeongyeon Hwang

Most state-of-the-art techniques for medical image segmentation rely on deep-learning models. These models, however, are often trained on narrowly-defined tasks in a supervised fashion, which requires expensive labeled datasets. Recent…

Image and Video Processing · Electrical Eng. & Systems 2023-10-04 Heejong Kim , Victor Ion Butoi , Adrian V. Dalca , Daniel J. A. Margolis , Mert R. Sabuncu