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Progress in biomedical Named Entity Recognition (NER) and Entity Linking (EL) is currently hindered by a fragmented data landscape, a lack of resources for building explainable models, and the limitations of semantically-blind evaluation…

Computation and Language · Computer Science 2025-11-17 Nishant Mishra , Wilker Aziz , Iacer Calixto

Multimodal Retrieval-Augmented Generation (MRAG) addresses key limitations of Multimodal Large Language Models (MLLMs), such as hallucination and outdated knowledge. However, current MRAG systems struggle to distinguish whether retrieved…

Computation and Language · Computer Science 2026-05-01 Xihang Wang , Zihan Wang , Chengkai Huang , Quan Z. Sheng , Lina Yao

Medical image segmentation has advanced rapidly over the past two decades, largely driven by deep learning, which has enabled accurate and efficient delineation of cells, tissues, organs, and pathologies across diverse imaging modalities.…

Image and Video Processing · Electrical Eng. & Systems 2025-08-29 Guoping Xu , Jayaram K. Udupa , Jax Luo , Songlin Zhao , Yajun Yu , Scott B. Raymond , Hao Peng , Lipeng Ning , Yogesh Rathi , Wei Liu , You Zhang

Semantic segmentation is crucial for medical image analysis, enabling precise disease diagnosis and treatment planning. However, many advanced models employ complex architectures, limiting their use in resource-constrained clinical…

Image and Video Processing · Electrical Eng. & Systems 2026-01-06 Le-Anh Tran , Chung Nguyen Tran , Nhan Cach Dang , Anh Le Van Quoc , Jordi Carrabina , David Castells-Rufas , Minh Son Nguyen

Diagnosing hepatic diseases accurately and interpretably is critical, yet it remains challenging in real-world clinical settings. Existing AI approaches for clinical diagnosis often lack transparency, structured reasoning, and…

Artificial Intelligence · Computer Science 2026-03-06 Zheng Li , Jiayi Xu , Zhikai Hu , Hechang Chen , Lele Cong , Yunyun Wang , Shuchao Pang

Large language models (LLMs) have shown promise in medical question answering but often struggle with hallucinations and shallow reasoning, particularly in tasks requiring nuanced clinical understanding. Retrieval-augmented generation (RAG)…

Computation and Language · Computer Science 2025-08-25 Ziyu Wang , Elahe Khatibi , Amir M. Rahmani

Multi-entity question answering (MEQA) represents significant challenges for large language models (LLM) and retrieval-augmented generation (RAG) systems, which frequently struggle to consolidate scattered information across diverse…

Computation and Language · Computer Science 2025-09-25 Teng Lin , Yuyu Luo , Honglin Zhang , Jicheng Zhang , Chunlin Liu , Kaishun Wu , Nan Tang

Training medical image segmentation models for rare yet clinically important imaging modalities is challenging due to the scarcity of annotated data, and manual mask annotations can be costly and labor-intensive to acquire. This paper…

Computer Vision and Pattern Recognition · Computer Science 2025-07-18 Haoning Wu , Ziheng Zhao , Ya Zhang , Yanfeng Wang , Weidi Xie

Large language models (LLMs) show increasing promise in medical applications, but their ability to detect and correct errors in clinical texts -- a prerequisite for safe deployment -- remains under-evaluated, particularly beyond English. We…

Computation and Language · Computer Science 2025-11-04 Naoto Iwase , Hiroki Okuyama , Junichiro Iwasawa

Medical image segmentation is a critical component in clinical practice, facilitating accurate diagnosis, treatment planning, and disease monitoring. However, existing methods, often tailored to specific modalities or disease types, lack…

Image and Video Processing · Electrical Eng. & Systems 2024-04-02 Jun Ma , Yuting He , Feifei Li , Lin Han , Chenyu You , Bo Wang

Continual learning protocols are attracting increasing attention from the medical imaging community. In continual environments, datasets acquired under different conditions arrive sequentially; and each is only available for a limited…

Computer Vision and Pattern Recognition · Computer Science 2023-02-13 Camila Gonzalez , Nick Lemke , Georgios Sakas , Anirban Mukhopadhyay

Recently, developing unified medical image segmentation models gains increasing attention, especially with the advent of the Segment Anything Model (SAM). SAM has shown promising binary segmentation performance in natural domains, however,…

Computer Vision and Pattern Recognition · Computer Science 2024-12-18 Shuangping Huang , Hao Liang , Qingfeng Wang , Chulong Zhong , Zijian Zhou , Miaojing Shi

Medical image segmentation faces a fundamental challenge in continual learning: data arrives sequentially from heterogeneous sources, yet effective continual learning requires discovering which tasks share sufficient structure to benefit…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Ziyuan Gao

Medical image segmentation is fundamental for biomedical discovery. Existing methods lack generalizability and demand extensive, time-consuming manual annotation for new clinical application. Here, we propose MedSAM-3, a text promptable…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Anglin Liu , Rundong Xue , Xu R. Cao , Yifan Shen , Yi Lu , Xiang Li , Qianqian Chen , Jintai Chen

Large language models (LLMs) have achieved strong performance on medical exam-style tasks, motivating growing interest in their deployment in real-world clinical settings. However, clinical decision-making is inherently safety-critical,…

Computation and Language · Computer Science 2026-04-13 Xiaohan Ren , Chenxiao Fan , Wenyin Ma , Hongliang He , Chongming Gao , Xiaoyan Zhao , Fuli Feng

Although perception systems have made remarkable advancements in recent years, they still rely on explicit human instruction or pre-defined categories to identify the target objects before executing visual recognition tasks. Such systems…

Computer Vision and Pattern Recognition · Computer Science 2024-05-02 Xin Lai , Zhuotao Tian , Yukang Chen , Yanwei Li , Yuhui Yuan , Shu Liu , Jiaya Jia

Volumetric Reasoning Segmentation (VRS) aims to segment a target region in a 3D medical scan from a free-form clinical query, where the referent is often implicit and requires both medical knowledge and volume-grounded reasoning. Existing…

Computer Vision and Pattern Recognition · Computer Science 2026-05-27 Zichun Wang , Hairong Shi , Bingzheng Wei , Yan Xu , Zihua Wang

Reasoning segmentation requires models to ground complex, implicit textual queries into precise pixel-level masks. Existing approaches rely on a single segmentation token $\texttt{<SEG>}$, whose hidden state implicitly encodes both semantic…

Computer Vision and Pattern Recognition · Computer Science 2026-04-23 Rui Qian , Chuanhang Deng , Qiang Huang , Jian Xiong , Mingxuan Li , Yingbo Zhou , Wei Zhai , Jintao Chen , Dejing Dou

Learning efficient representations for concepts has been proven to be an important basis for many applications such as machine translation or document classification. Proper representations of medical concepts such as diagnosis, medication,…

Machine Learning · Computer Science 2016-02-18 Edward Choi , Mohammad Taha Bahadori , Elizabeth Searles , Catherine Coffey , Jimeng Sun

Medical imaging research has spent a decade getting very good at one thing: producing per-voxel masks. Masks tell us size, volume, and location, and a decade of clinical infrastructure rests on those outputs. Yet the report a radiologist…

Computer Vision and Pattern Recognition · Computer Science 2026-05-13 Siddharth Gupta , Alan L. Yuille , Zongwei Zhou
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