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Microservices are widely adopted in modern cloud systems due to their scalability and fault tolerance. However, microservice architectures introduce significant complexity in privilege and permission control, creating risks of privilege…

Cryptography and Security · Computer Science 2026-05-18 Penghui Li , Hong Yau Chong , Yinzhi Cao , Junfeng Yang

Autonomous agents play a crucial role in advancing Artificial General Intelligence, enabling problem decomposition and tool orchestration through Large Language Models (LLMs). However, existing paradigms face a critical trade-off. On one…

Artificial Intelligence · Computer Science 2025-09-03 Jinzhou Tang , Jusheng Zhang , Qinhan Lv , Sidi Liu , Jing Yang , Chengpei Tang , Keze Wang

The rapid deployment of AI agents in commercial settings has outpaced the development of evaluation methodologies that reflect production realities. Existing benchmarks measure agent capabilities through retrospectively curated tasks with…

The Nova Synthetic Data Base (NSDB) is presented as the first publicly available database of synthetic spectra for classical nova shells, spanning an unprecedented range of physical parameters (e.g., ejecta mass, chemical composition,…

Solar and Stellar Astrophysics · Physics 2026-05-18 Bruno C. Santos , Marcos P. Diaz , Larissa Takeda

Real-world multimodal agents solve multi-step workflows grounded in visual evidence. For example, an agent can troubleshoot a device by linking a wiring photo to a schematic and validating the fix with online documentation, or plan a trip…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Zhaochen Su , Jincheng Gao , Hangyu Guo , Zhenhua Liu , Lueyang Zhang , Xinyu Geng , Shijue Huang , Peng Xia , Guanyu Jiang , Cheng Wang , Yue Zhang , Yi R. Fung , Junxian He

Biomedical imaging is a driver of scientific discovery and core component of medical care, currently stimulated by the field of deep learning. While semantic segmentation algorithms enable 3D image analysis and quantification in many…

Computer Vision and Pattern Recognition · Computer Science 2020-12-09 Fabian Isensee , Paul F. Jäger , Simon A. A. Kohl , Jens Petersen , Klaus H. Maier-Hein

Despite the promises of data-driven artificial intelligence (AI), little is known about how we can bridge the gulf between traditional physician-driven diagnosis and a plausible future of medicine automated by AI. Specifically, how can we…

Human-Computer Interaction · Computer Science 2021-02-12 Hongyan Gu , Jingbin Huang , Lauren Hung , Xiang 'Anthony' Chen

From the original abstract: This thesis initially aims to study the pain assessment process from a clinical-theoretical perspective while exploring and examining existing automatic approaches. Building on this foundation, the primary…

Artificial Intelligence · Computer Science 2025-05-13 Stefanos Gkikas

Unstructured notes within the electronic health record (EHR) contain rich clinical information vital for cancer treatment decision making and research, yet reliably extracting structured oncology data remains challenging due to extensive…

Topology optimization can generate efficient structures, but designers often must manually translate qualitative intent, such as desired visual style, product experience, or manufacturability into solver settings that are not directly tied…

Artificial Intelligence · Computer Science 2026-05-22 Isabella A. Stewart , Hongrui Chen , Faez Ahmed

Federated learning (FL) for histopathology image segmentation involving multiple medical sites plays a crucial role in advancing the field of accurate disease diagnosis and treatment. However, it is still a task of great challenges due to…

Image and Video Processing · Electrical Eng. & Systems 2023-12-21 Yuan Zhang , Yaolei Qi , Xiaoming Qi , Lotfi Senhadji , Yongyue Wei , Feng Chen , Guanyu Yang

The rapid digitization of histopathology slides has opened up new possibilities for computational tools in clinical and research workflows. Among these, content-based slide retrieval stands out, enabling pathologists to identify…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Hongyi Wang , Zhengjie Zhu , Jiabo Ma , Fang Wang , Yue Shi , Bo Luo , Jili Wang , Qiuyu Cai , Xiuming Zhang , Yen-Wei Chen , Lanfen Lin , Hao Chen

In this paper, we present NEMO, a system that translates Natural-language descriptions of decision problems into formal Executable Mathematical Optimization implementations, operating collaboratively with users or autonomously. Existing…

Artificial Intelligence · Computer Science 2026-01-30 Yang Song , Anoushka Vyas , Zirui Wei , Sina Khoshfetrat Pakazad , Henrik Ohlsson , Graham Neubig

Edge computing breaks with traditional autoscaling due to strict resource constraints, thus, motivating more flexible scaling behaviors using multiple elasticity dimensions. This work introduces an agent-based autoscaling framework that…

Artificial Intelligence · Computer Science 2026-01-13 Boris Sedlak , Alireza Furutanpey , Zihang Wang , Víctor Casamayor Pujol , Schahram Dustdar

Motivation: Agent-based modeling is an indispensable tool for studying complex biological systems. However, existing simulators do not always take full advantage of modern hardware and often have a field-specific software design. Results:…

Accurate segmentation and classification of nuclei in histology images is critical but challenging due to nuclei heterogeneity, staining variations, and tissue complexity. Existing methods often struggle with limited dataset variability,…

Image and Video Processing · Electrical Eng. & Systems 2025-01-22 Wenhua Zhang , Sen Yang , Meiwei Luo , Chuan He , Yuchen Li , Jun Zhang , Xiyue Wang , Fang Wang

Computational pathology foundation models (CPathFMs) have emerged as a powerful approach for analyzing histopathological data, leveraging self-supervised learning to extract robust feature representations from unlabeled whole-slide images.…

Computer Vision and Pattern Recognition · Computer Science 2025-02-27 Dong Li , Guihong Wan , Xintao Wu , Xinyu Wu , Ajit J. Nirmal , Christine G. Lian , Peter K. Sorger , Yevgeniy R. Semenov , Chen Zhao

To achieve minimum DNA input and tumor purity requirements for next-generation sequencing (NGS), pathologists visually estimate macrodissection and slide count decisions. Misestimation may cause tissue waste and increased laboratory costs.…

Artificial RNA molecules with novel functionality have many applications in synthetic biology, pharmacy and white biotechnology. The de novo design of such devices using computational methods and prediction tools is a resource-efficient…

Biomolecules · Quantitative Biology 2019-05-13 Stefan Hammer , Christian Günzel , Mario Mörl , Sven Findeiß

We present a pioneering investigation into the application of deep learning techniques to analyze histopathological images for addressing the substantial challenge of automated prognostic prediction. Prognostic prediction poses a unique…

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