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Recently, self-supervised instance discrimination methods have achieved significant success in learning visual representations from unlabeled photographic images. However, given the marked differences between photographic and medical…

Image and Video Processing · Electrical Eng. & Systems 2022-04-18 Mohammad Reza Hosseinzadeh Taher , Fatemeh Haghighi , Michael B. Gotway , Jianming Liang

Since the emergence of the ImageNet dataset, the pretraining and fine-tuning approach has become widely adopted in computer vision due to the ability of ImageNet-pretrained models to learn a wide variety of visual features. However, a…

Computer Vision and Pattern Recognition · Computer Science 2024-10-22 Pablo Meseguer , Rocío del Amor , Adrian Colomer , Valery Naranjo

Class-incremental learning (CIL) in medical image-guided diagnosis requires retaining prior diagnostic knowledge while adapting to newly emerging disease categories, which is critical for scalable clinical deployment. This problem is…

Computer Vision and Pattern Recognition · Computer Science 2026-03-26 Xinyao Wu , Zhe Xu , Cheng Chen , Jiawei Ma , Yefeng Zheng , Raymond Kai-yu Tong

Deep learning methods are widely used for medical applications to assist medical doctors in their daily routines. While performances reach expert's level, interpretability (highlight how and what a trained model learned and why it makes a…

Computer Vision and Pattern Recognition · Computer Science 2020-09-30 Antoine Pirovano , Hippolyte Heuberger , Sylvain Berlemont , Saïd Ladjal , Isabelle Bloch

Multiple Instance Learning (MIL) has been widely applied in histopathology to classify Whole Slide Images (WSIs) with slide-level diagnoses. While the ground truth is established by expert pathologists, the slides can be difficult to…

Computer Vision and Pattern Recognition · Computer Science 2026-03-11 Marie Arrivat , Rémy Peyret , Elsa Angelini , Pietro Gori

The emergence of foundation models in computational pathology has transformed histopathological image analysis, with whole slide imaging (WSI) diagnosis being a core application. Traditionally, weakly supervised fine-tuning via multiple…

Computer Vision and Pattern Recognition · Computer Science 2025-03-03 Jiawen Li , Jiali Hu , Qiehe Sun , Renao Yan , Minxi Ouyang , Tian Guan , Anjia Han , Chao He , Yonghong He

Multimodal machine learning integrating histopathology and molecular data shows promise for cancer prognostication. We systematically reviewed studies combining whole slide images (WSIs) and high-throughput omics to predict overall…

Quantitative Methods · Quantitative Biology 2025-07-30 Charlotte Jennings , Andrew Broad , Lucy Godson , Emily Clarke , David Westhead , Darren Treanor

Early diagnosis of lung cancer is a key intervention for the treatment of lung cancer computer aided diagnosis (CAD) can play a crucial role. However, most published CAD methods treat lung cancer diagnosis as a lung nodule classification…

Image and Video Processing · Electrical Eng. & Systems 2022-10-12 Junhua Chen , Haiyan Zeng , Chong Zhang , Zhenwei Shi , Andre Dekker , Leonard Wee , Inigo Bermejo

Pathology foundation models (PFMs) have emerged as powerful tools for analyzing whole slide images (WSIs). However, adapting these pretrained PFMs for specific clinical tasks presents considerable challenges, primarily due to the…

Computer Vision and Pattern Recognition · Computer Science 2025-06-06 Neeraj Kumar , Swaraj Nanda , Siddharth Singi , Jamal Benhamida , David Kim , Jie-Fu Chen , Amir Momeni-Boroujeni , Gregory M. Goldgof , Gabriele Campanella , Chad Vanderbilt

Multimodal in-context learning (ICL) remains underexplored despite significant potential for domains such as medicine. Clinicians routinely encounter diverse, specialized tasks requiring adaptation from limited examples, such as drawing…

Current cervical cytopathology whole slide image (WSI) screening primarily relies on detection-based approaches, which are limited in performance due to the expense and time-consuming annotation process. Multiple Instance Learning (MIL), a…

Computer Vision and Pattern Recognition · Computer Science 2024-07-17 Jialong Huang , Gaojie Li , Shichao Kan , Jianfeng Liu , Yixiong Liang

Weakly supervised whole slide image classification is usually formulated as a multiple instance learning (MIL) problem, where each slide is treated as a bag, and the patches cut out of it are treated as instances. Existing methods either…

Computer Vision and Pattern Recognition · Computer Science 2024-05-14 Linhao Qu , Yingfan Ma , Xiaoyuan Luo , Manning Wang , Zhijian Song

Multiple instance learning (MIL) is a framework for weakly supervised classification, where labels are assigned to sets of instances, i.e., bags, rather than to individual data points. This paradigm has proven effective in tasks where…

Machine Learning · Computer Science 2026-03-03 Salome Kazeminia , Carsten Marr , Bastian Rieck

We propose Spatial-Aware Correlated Multiple Instance Learning (SAC-MIL) for performing WSI classification. SAC-MIL consists of a positional encoding module to encode position information and a SAC block to perform full instance…

Computer Vision and Pattern Recognition · Computer Science 2025-09-05 Yu Bai , Zitong Yu , Haowen Tian , Xijing Wang , Shuo Yan , Lin Wang , Honglin Li , Xitong Ling , Bo Zhang , Zheng Zhang , Wufan Wang , Hui Gao , Xiangyang Gong , Wendong Wang

Vision-Language Models (VLMs), such as CLIP, have demonstrated remarkable zero-shot capabilities in various computer vision tasks. However, their application to medical imaging remains challenging due to the high variability and complexity…

Computer Vision and Pattern Recognition · Computer Science 2026-05-15 Xusheng Liang , Lihua Zhou , Nianxin Li , Miao Xu , Ziyang Song , Dong Yi , Jinlin Wu , Jiawei Ma , Hongbin Liu , Zhen Lei , Jiebo Luo

Multiple Instance Learning (MIL) is a sub-domain of classification problems with positive and negative labels and a "bag" of inputs, where the label is positive if and only if a positive element is contained within the bag, and otherwise is…

Machine Learning · Statistics 2023-10-30 Edward Raff , James Holt

Multimodalpersonalityunderstandingplaysacriticalroleinhuman centered artificial intelligence. Previous work mainly focus on learn-ing rich multimodal representations for video personality under standing. However, they often suffer from…

Artificial Intelligence · Computer Science 2026-05-08 Yangfu Zhu , Zitong Han , Nianwen Ning , Yuting Wei , Yuandong Wang , Hang Feng , Zhenzhou Shao

Lung adenocarcinoma (LUAD) grading depends on accurately identifying growth patterns, which are indicators of prognosis and can influence treatment decisions. Common deep learning approaches to determine the predominant pattern rely on…

Computer Vision and Pattern Recognition · Computer Science 2026-04-24 Laura Valeria Perez-Herrera , M. J. Garcia-Gonzalez , Karen Lopez-Linares

Deep learning has brought significant progress to medical image classification, yet most existing methods still rely on isolated visual evidence and cannot effectively leverage similar cases or external knowledge. In clinical practice,…

Computer Vision and Pattern Recognition · Computer Science 2026-05-28 Yiming Xu , Yixuan Liu , Yuhang Zhang , Ling Zheng , Yihan Wang , Qi Song

Weakly Supervised Video Anomaly Detection (WSVAD) is challenging because the binary anomaly label is only given on the video level, but the output requires snippet-level predictions. So, Multiple Instance Learning (MIL) is prevailing in…

Computer Vision and Pattern Recognition · Computer Science 2023-03-23 Hui Lv , Zhongqi Yue , Qianru Sun , Bin Luo , Zhen Cui , Hanwang Zhang
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