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Synthetic data generation using large language models (LLMs) demonstrates substantial promise in addressing biomedical data challenges and shows increasing adoption in biomedical research. This study systematically reviews recent advances…

Computation and Language · Computer Science 2026-02-18 Hanshu Rao , Weisi Liu , Haohan Wang , I-Chan Huang , Zhe He , Xiaolei Huang

When developing devices, architectures and services for the Internet of Medical Things (IoMT) world, manufacturers or integrators must be aware of the security requirements expressed by both laws and specifications. To provide tools guiding…

Cryptography and Security · Computer Science 2025-01-07 Daniel Naro , Jaime Delgado , Silvia Llorente , Amanda Palomo

Text-to-SQL, the task of translating natural language questions into SQL queries, plays a crucial role in enabling non-experts to interact with databases. While recent advancements in large language models (LLMs) have significantly enhanced…

Computation and Language · Computer Science 2025-07-15 Haoyang Li , Shang Wu , Xiaokang Zhang , Xinmei Huang , Jing Zhang , Fuxin Jiang , Shuai Wang , Tieying Zhang , Jianjun Chen , Rui Shi , Hong Chen , Cuiping Li

In the intricate domain of software systems verification, dynamically model checking multifaceted system characteristics remains paramount, yet challenging. This research proposes the advanced observe-based statistical model-checking (OSM)…

Software Engineering · Computer Science 2024-03-05 Anas AlSobeh

Structured data offers a sophisticated mechanism for the organization of information. Existing methodologies for the text-serialization of structured data in the context of large language models fail to adequately address the heterogeneity…

Computation and Language · Computer Science 2024-02-20 YiQiu Guo , Yuchen Yang , Ya Zhang , Yu Wang , Yanfeng Wang

Achieving semantic interoperability across heterogeneous experimental data systems remains a major barrier to data-driven scientific discovery. The Analytical Information Markup Language (AnIML), a flexible XML-based standard for analytical…

High-dimensional omics data contains intrinsic biomedical information that is crucial for personalised medicine. Nevertheless, it is challenging to capture them from the genome-wide data due to the large number of molecular features and…

Genomics · Quantitative Biology 2021-06-22 Xiaoyu Zhang , Yuting Xing , Kai Sun , Yike Guo

Information extraction from copy-heavy documents, characterized by massive volumes of structurally similar content, represents a critical yet understudied challenge in enterprise document processing. We present a systematic framework that…

Computation and Language · Computer Science 2025-10-14 Zilong Wang , Xiaoyu Shen

Semi-supervised learning has become increasingly popular in medical image segmentation due to its ability to leverage large amounts of unlabeled data to extract additional information. However, most existing semi-supervised segmentation…

Computer Vision and Pattern Recognition · Computer Science 2023-07-13 Shengbo Gao , Ziji Zhang , Jiechao Ma , Zihao Li , Shu Zhang

Today cloud computing infrastructure is largely being deployed in healthcare to access various healthcare services easily over the Internet on an as needed basis. The main advantage of healthcare cloud is that it can be used as a tool for…

Computers and Society · Computer Science 2014-10-23 Santosh Kumar Majhi , Padmalochan Bera

Biomedical segmentation networks easily suffer from the unexpected misclassification between foreground and background objects when learning on limited and imperfect medical datasets. Inspired by the strong power of Out-of-Distribution…

Computer Vision and Pattern Recognition · Computer Science 2025-07-17 Yiquan Gao , Duohui Xu

The objective of this work is to develop an Electronic Medical Record (EMR) data processing tool that confers clinical context to Machine Learning (ML) algorithms for error handling, bias mitigation and interpretability. We present…

Electronic health records (EHRs) contain vast amounts of complex data, but harmonizing and processing this information remains a challenging and costly task requiring significant clinical expertise. While large language models (LLMs) have…

Computation and Language · Computer Science 2024-07-02 João Matos , Jack Gallifant , Jian Pei , A. Ian Wong

Demand for enterprise data warehouse solutions to support real-time Online Transaction Processing (OLTP) queries as well as long-running Online Analytical Processing (OLAP) workloads is growing. Greenplum database is traditionally known as…

Objective: Electronic health records (EHR) data are prone to missingness and errors. Previously, we devised an "enriched" chart review protocol where a "roadmap" of auxiliary diagnoses (anchors) was used to recover missing values in EHR…

Machine Learning · Computer Science 2025-10-07 Sarah C. Lotspeich , Abbey Collins , Brian J. Wells , Ashish K. Khanna , Joseph Rigdon , Lucy D'Agostino McGowan

Starting from version 2.0, UML introduced hierarchical composite structures, which are an expressive way of defining complex software architectures, but which have a very loosely defined semantics in the standard. In this paper we propose a…

Software Engineering · Computer Science 2010-11-01 Iulia Dragomir , Iulian Ober

Deep learning models exhibit state-of-the-art performance for many predictive healthcare tasks using electronic health records (EHR) data, but these models typically require training data volume that exceeds the capacity of most healthcare…

Machine Learning · Computer Science 2018-10-24 Edward Choi , Cao Xiao , Walter F. Stewart , Jimeng Sun

Background: Patient recruitment in clinical trials is hindered by complex eligibility criteria and labor-intensive chart reviews. Prior research using text-only models have struggled to address this problem in a reliable and scalable way…

Computation and Language · Computer Science 2025-03-20 Anatole Callies , Quentin Bodinier , Philippe Ravaud , Kourosh Davarpanah

Background: Large language models (LLMs) show promise in medicine, but their deployment in hospitals is limited by restricted access to electronic health record (EHR) systems. The Model Context Protocol (MCP) enables integration between…

Artificial Intelligence · Computer Science 2025-09-22 Kanato Masayoshi , Masahiro Hashimoto , Ryoichi Yokoyama , Naoki Toda , Yoshifumi Uwamino , Shogo Fukuda , Ho Namkoong , Masahiro Jinzaki

The ability of large language models (LLMs) to follow natural language instructions with human-level fluency suggests many opportunities in healthcare to reduce administrative burden and improve quality of care. However, evaluating LLMs on…