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Clinical reports are often fragmented across healthcare institutions because privacy regulations and data silos limit direct information sharing. When patients seek care at a different hospital, they often carry paper or scanned reports…

Computation and Language · Computer Science 2026-05-12 Yu Wang , Yingyun Li , Ying Qin , Haiyang Qian

Given the increasing complexity of omics datasets, a key challenge is not only improving classification performance but also enhancing the transparency and reliability of model decisions. Effective model performance and feature selection…

Machine Learning · Computer Science 2025-05-07 Diego Perazzolo , Pietro Fanton , Ilaria Barison , Marny Fedrigo , Annalisa Angelini , Chiara Castellani , Enrico Grisan

Large language models (LLMs) are increasingly used to extract clinical data from electronic health records (EHRs), offering significant improvements in scalability and efficiency for real-world data (RWD) curation in oncology. However, the…

Despite the rapid development of large language models (LLMs), a fundamental challenge persists: the lack of high-quality optimization modeling datasets hampers LLMs' robust modeling of practical optimization problems from natural language…

Artificial Intelligence · Computer Science 2025-02-24 Hongliang Lu , Zhonglin Xie , Yaoyu Wu , Can Ren , Yuxuan Chen , Zaiwen Wen

As two important textual modalities in electronic health records (EHR), both structured data (clinical codes) and unstructured data (clinical narratives) have recently been increasingly applied to the healthcare domain. Most existing…

Computation and Language · Computer Science 2022-11-01 Sicen Liu , Xiaolong Wang , Yongshuai Hou , Ge Li , Hui Wang , Hui Xu , Yang Xiang , Buzhou Tang

Background: Electronic health records (EHRs) enable machine learning for diagnosis, prognosis, and clinical decision support. However, EHR standards vary by country and hospital, making records often incompatible. This limits large-scale…

Information Retrieval · Computer Science 2026-03-27 Jiawei Zhao , Md Shamim Ahmed , Nicolai Dinh Khang Truong , Verena Schuster , Rudolf Mayer , Richard Röttger

Individuals and organizations cope with an always-growing amount of data, which is heterogeneous in its contents and formats. An adequate data management process yielding data quality and control over its lifecycle is a prerequisite to…

The increasing use of Electronic Health Records (EHR) has emphasized the need for standardization and interoperability in healthcare data management. The Ministry of Health and Family Welfare, Government of India, has introduced the…

Information Retrieval · Computer Science 2025-04-15 Biswanath Dutta , Debanjali Bain

The biomedical literature contains a vast collection of omics studies, yet most published data remain functionally inaccessible for computational reuse. When raw data are deposited in public repositories, essential information for…

Genomics · Quantitative Biology 2026-03-16 Alexandre Hutton , Jesse G. Meyer

Despite their success, Machine Learning (ML) models do not generalize effectively to data not originating from the training distribution. To reliably employ ML models in real-world healthcare systems and avoid inaccurate predictions on…

Machine Learning · Computer Science 2023-09-29 Mohammad Azizmalayeri , Ameen Abu-Hanna , Giovanni Ciná

Machine learning (ML) approaches have demonstrated promising results in a wide range of healthcare applications. Data plays a crucial role in developing ML-based healthcare systems that directly affect people's lives. Many of the ethical…

The heterogeneity of data poses a great challenge when data from different sources is to be merged for one application. Solutions for this are offered, for example, by ontology-based data management (OBDM). A challenge of OBDM is the…

Information Retrieval · Computer Science 2020-05-15 Andreas Burgdorf , André Pomp , Tobias Meisen

Clinicians are interested in better understanding complex diseases, such as cancer or rare diseases, so they need to produce and exchange data to mutualize sources and join forces. To do so and ensure privacy, a natural way consists in…

Databases · Computer Science 2025-09-29 Nelly Barret , Anna Bernasconi , Boris Bikbov , Pietro Pinoli

Healthcare providers face significant challenges with monitoring and managing patient data outside of clinics, particularly with insufficient resources and limited feedback on their patients' conditions. Effective management of these…

Databases · Computer Science 2023-11-14 Daniel Bloor , Nnamdi Ugwuoke , David Taylor , Keir Lewis , Luis Mur , Chuan Lu

In this paper, we propose a framework that incorporates experts diagnostics and insights into the analysis of Optical Coherence Tomography (OCT) using multi-modal learning. To demonstrate the effectiveness of this approach, we create a…

Image and Video Processing · Electrical Eng. & Systems 2022-03-22 Y. Logan , K. Kokilepersaud , G. Kwon , G. AlRegib , C. Wykoff , H. Yu

Multimodal Large Language Models (MLLMs) have shown transformative potential in medical applications, yet their performance is hindered by conventional data curation strategies that rely on coarse-grained partitioning by modality or…

Computation and Language · Computer Science 2026-04-29 Jianghang Lin , Haihua Yang , Deli Yu , Kai Wu , Kai Ye , Jinghao Lin , Zihan Wang , Yuhang Wu , Liujuan Cao

The potential benefits of applying machine learning methods to -omics data are becoming increasingly apparent, especially in clinical settings. However, the unique characteristics of these data are not always well suited to machine learning…

Large Language Models (LLMs) have shown remarkable capabilities for complex tasks, yet adaptation in medical domain, specifically mental health, poses specific challenges. Mental health is a rising concern globally with LLMs having large…

By 2025, there are zettabytes of data generated every year. The size and complexity of modern large-scale computing infrastructures like High-Performance Computing (HPC) systems continue to evolve and become complex, leaving us wondering…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-03-20 Shekhar Suman , Xiaoyu Chu , Alexandru Iosup