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Protein fitness optimization involves finding a protein sequence that maximizes desired quantitative properties in a combinatorially large design space of possible sequences. Recent advances in steering protein generative models (e.g.,…

Biomolecules · Quantitative Biology 2025-10-22 Jason Yang , Wenda Chu , Daniel Khalil , Raul Astudillo , Bruce J. Wittmann , Frances H. Arnold , Yisong Yue

Large reasoning models (LRMs), such as OpenAI o1 and DeepSeek-R1, have significantly enhanced their reasoning capabilities by generating longer chains of thought, demonstrating outstanding performance across a variety of tasks. However,…

Computation and Language · Computer Science 2025-10-31 Haoran Zhao , Yuchen Yan , Yongliang Shen , Haolei Xu , Wenqi Zhang , Kaitao Song , Jian Shao , Weiming Lu , Jun Xiao , Yueting Zhuang

Recent work on domain-specific reasoning with large language models (LLMs) often relies on training-intensive approaches that require parameter updates. While activation steering has emerged as a parameter efficient alternative, existing…

Artificial Intelligence · Computer Science 2026-01-21 Wencheng Ye , Xiaoyang Yuan , Yi Bin , Pengpeng Zeng , Hengyu Jin , Liang Peng , Heng Tao Shen

Test-time scaling (TTS) has been shown to improve the performance of large language models (LLMs) by sampling and aggregating diverse reasoning paths. However, existing research has overlooked a critical issue: selection bias of reasoning…

Artificial Intelligence · Computer Science 2025-09-24 Zongqian Wu , Baoduo Xu , Tianyu Li , Zhu Sun , Xiaofeng Zhu , Lei Feng

Reasoning Large Language Models (LLMs) enable test-time scaling, with dataset-level accuracy improving as the token budget increases, motivating adaptive reasoning -- spending tokens when they improve reliability and stopping early when…

Artificial Intelligence · Computer Science 2026-05-15 Xi Wang , Anushri Suresh , Alvin Zhang , Rishi More , William Jurayj , Benjamin Van Durme , Mehrdad Farajtabar , Daniel Khashabi , Eric Nalisnick

Spiking neural networks (SNNs) are recurrent models that can leverage sparsity in input time series to efficiently carry out tasks such as classification. Additional efficiency gains can be obtained if decisions are taken as early as…

Neural and Evolutionary Computing · Computer Science 2023-12-19 Jiechen Chen , Sangwoo Park , Osvaldo Simeone

Steering resources, central for quantum advantages in one-sided device-independent quantum information tasks, can be enhanced via local filters. Recently, reversible steering conversion under local filters has been fully characterised.…

Quantum Physics · Physics 2023-09-13 Chung-Yun Hsieh , Huan-Yu Ku , Costantino Budroni

Beam search is a go-to strategy for decoding neural sequence models. The algorithm can naturally be viewed as a subset optimization problem, albeit one where the corresponding set function does not reflect interactions between candidates.…

Computation and Language · Computer Science 2023-06-26 Clara Meister , Martina Forster , Ryan Cotterell

Increasing test-time computation has emerged as a promising direction for improving language model performance, particularly in scenarios where model finetuning is impractical or impossible due to computational constraints or private model…

Computation and Language · Computer Science 2025-12-22 Gonçalo Faria , Noah A. Smith

Optimal stopping is the problem of deciding when to stop a stochastic system to obtain the greatest reward, arising in numerous application areas such as finance, healthcare and marketing. State-of-the-art methods for high-dimensional…

Optimization and Control · Mathematics 2020-01-01 Dragos Florin Ciocan , Velibor V. Mišić

Large Language Models (LLMs), despite advances in instruction tuning, often fail to follow complex user instructions. Activation steering techniques aim to mitigate this by manipulating model internals, but have a potential risk of…

Machine Learning · Computer Science 2026-03-10 Minjae Kang , Jaehyung Kim

Retrieval-augmented generation (RAG) has become a widely adopted paradigm for enabling knowledge-grounded large language models (LLMs). However, standard RAG pipelines often fail to ensure that model reasoning remains consistent with the…

Artificial Intelligence · Computer Science 2025-10-14 Jiaqi Wei , Hao Zhou , Xiang Zhang , Di Zhang , Zijie Qiu , Wei Wei , Jinzhe Li , Wanli Ouyang , Siqi Sun

Spiking neural networks (SNNs) promise low-power event-driven computation for temporally rich tasks, but commonly used neuron models often trade off gradient-based trainability, dynamical richness, and high activity sparsity. These…

Neural and Evolutionary Computing · Computer Science 2026-05-13 Alex Fulleda-Garcia , Saray Soldado-Magraner , Josep Maria Margarit-Taulé

Inference-time LLM alignment methods, particularly activation steering, offer an alternative to fine-tuning by directly modifying activations during generation. Existing methods, however, often rely on non-anticipative interventions that…

Machine Learning · Computer Science 2026-04-22 Julian Skifstad , Xinyue Annie Yang , Glen Chou

Sparse autoencoders (SAEs) have recently emerged as a powerful tool for language model steering. Prior work has explored top-k SAE latents for steering, but we observe that many dimensions among the top-k latents capture non-semantic…

Computation and Language · Computer Science 2025-10-03 Jiaqing Xie

Alignment in LLMs is more brittle than commonly assumed: misalignment can be triggered by adversarial prompts, benign fine-tuning, emergent misalignment, and goal misgeneralization. Recent evidence suggests that some misalignment behaviors…

Artificial Intelligence · Computer Science 2026-04-10 Niklas Herbster , Martin Zborowski , Alberto Tosato , Gauthier Gidel , Tommaso Tosato

Chain-of-thought (CoT) reasoning in large language models (LLMs) can be formalized as a latent variable problem, where the model needs to generate intermediate reasoning steps. While prior approaches such as iterative reward-ranked…

Machine Learning · Computer Science 2025-05-06 Jiarui Yao , Yifan Hao , Hanning Zhang , Hanze Dong , Wei Xiong , Nan Jiang , Tong Zhang

Exploration capacity shapes both inference-time performance and reinforcement learning (RL) training for large (vision-) language models, as stochastic sampling often yields redundant reasoning paths with little high-level diversity. This…

Computer Vision and Pattern Recognition · Computer Science 2025-12-22 Rujiao Long , Yang Li , Xingyao Zhang , Weixun Wang , Tianqianjin Lin , Xi Zhao , Yuchi Xu , Wenbo Su , Junchi Yan , Bo Zheng

Activation steering methods control large language model (LLM) behavior by modifying internal activations at inference time. However, most existing activation steering methods rely on a fixed steering strength, leading to either…

Computation and Language · Computer Science 2025-10-16 Arthur Vogels , Benjamin Wong , Yann Choho , Annabelle Blangero , Milan Bhan

Reinforcement learning (RL) training of large language models (LLMs) on unverifiable tasks is challenging even when a reasonable-quality reference answer is available. We propose a constrained RL training framework that (i) optimizes a…