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Linear Mixed Models (LMMs) are important tools in statistical genetics. When used for feature selection, they allow to find a sparse set of genetic traits that best predict a continuous phenotype of interest, while simultaneously correcting…

Large language models (LLMs) have achieved great success in medical question answering and clinical decision-making, promoting the efficiency and popularization of the personalized virtual doctor in society. However, the traditional…

Computation and Language · Computer Science 2025-09-23 Jianbin Zhang , Yulin Zhu , Wai Lun Lo , Richard Tai-Chiu Hsung , Harris Sik-Ho Tsang , Kai Zhou

Protein language models (PLMs) have demonstrated remarkable success in protein modeling and design, yet their internal mechanisms for predicting structure and function remain poorly understood. Here we present a systematic approach to…

Biomolecules · Quantitative Biology 2024-12-18 Elana Simon , James Zou

Learning human preferences in language models remains fundamentally challenging, as reward modeling relies on subtle, subjective comparisons or shades of gray rather than clear-cut labels. This study investigates the limits of current…

Computation and Language · Computer Science 2026-04-03 Simona-Vasilica Oprea , Adela Bâra

Reward models (RMs) play a pivotal role in aligning large language models (LLMs) with human preferences. However, traditional RM training, which relies on response pairs tied to specific prompts, struggles to disentangle prompt-driven…

To truly understand vision models, we must not only interpret their learned features but also validate these interpretations through controlled experiments. While earlier work offers either rich semantics or direct control, few post-hoc…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Samuel Stevens , Wei-Lun Chao , Tanya Berger-Wolf , Yu Su

Reinforcement learning (RL) has recently proven great success in various domains. Yet, the design of the reward function requires detailed domain expertise and tedious fine-tuning to ensure that agents are able to learn the desired…

Robotics · Computer Science 2023-03-06 Murad Dawood , Nils Dengler , Jorge de Heuvel , Maren Bennewitz

Predicting earnings surprises from financial documents, such as earnings conference calls, regulatory filings, and financial news, has become increasingly important in financial economics. However, these financial documents present…

Computational Finance · Quantitative Finance 2025-10-08 Huopu Zhang , Yanguang Liu , Miao Zhang , Zirui He , Mengnan Du

Aligning language models (LMs) based on human-annotated preference data is a crucial step in obtaining practical and performant LM-based systems. However, multilingual human preference data are difficult to obtain at scale, making it…

Computation and Language · Computer Science 2024-10-15 Zhaofeng Wu , Ananth Balashankar , Yoon Kim , Jacob Eisenstein , Ahmad Beirami

Reward models (RMs) are central to aligning large language models (LLMs) with human preferences, powering RLHF and advanced decoding strategies. While most prior work focuses on single-step generation, real-world applications increasingly…

Artificial Intelligence · Computer Science 2026-04-21 Xingyu Fan , Wei Shao , Jiacheng Liu , Linqi Song , Pheng Ann Heng

Reward models (RMs) have become essential for aligning large language models (LLMs), serving as scalable proxies for human evaluation in both training and inference. However, existing RMs struggle on knowledge-intensive and long-form tasks,…

Computation and Language · Computer Science 2025-10-30 Ziyou Hu , Zhengliang Shi , Minghang Zhu , Haitao Li , Teng Sun , Pengjie Ren , Suzan Verberne , Zhaochun Ren

Conventional research on large language models (LLMs) has primarily focused on refining output distributions, while paying less attention to the decoding process that transforms these distributions into final responses. Recent advances,…

Computation and Language · Computer Science 2025-10-28 Chenheng Zhang , Tianqi Du , Jizhe Zhang , Mingqing Xiao , Yifei Wang , Yisen Wang , Zhouchen Lin

Large Language Models (LLMs) offer extensive knowledge across various domains, but they may inadvertently memorize sensitive, unauthorized, or malicious data, such as personal information in the medical and financial sectors. Machine…

Computation and Language · Computer Science 2024-10-16 YuXuan Wu , Bonaventure F. P. Dossou , Dianbo Liu

We introduce the Parent-Guided Semantic Reward Model (PGSRM), a lightweight reward framework for reinforcement learning (RL) of transformer language models. PGSRM replaces binary correctness signals, human preference data, and trained…

Machine Learning · Computer Science 2025-12-09 Alexandr Plashchinsky

Reward models (RMs) are a crucial component in the alignment of large language models' (LLMs) outputs with human values. RMs approximate human preferences over possible LLM responses to the same prompt by predicting and comparing reward…

Machine Learning · Computer Science 2025-02-27 Junqi Jiang , Tom Bewley , Saumitra Mishra , Freddy Lecue , Manuela Veloso

Sparse autoencoders (SAEs) are widely used in mechanistic interpretability to project LLM activations onto sparse latent spaces. However, sparsity alone is an imperfect proxy for interpretability, and current training objectives often…

Machine Learning · Computer Science 2026-04-09 Vivek Narayanaswamy , Kowshik Thopalli , Bhavya Kailkhura , Wesam Sakla

Sparse autoencoders (SAEs) \citep{bricken2023monosemanticity,gao2024scalingevaluatingsparseautoencoders} rely on dictionary learning to extract interpretable features from neural networks at scale in an unsupervised manner, with…

Machine Learning · Computer Science 2025-05-02 Hans Peter , Anders Søgaard

Post-training alignment of video generation models with human preferences is a critical goal. Developing effective Reward Models (RMs) for this process faces significant methodological hurdles. Current data collection paradigms, reliant on…

Machine Learning · Computer Science 2026-03-17 Jiesong Lian , Ruizhe Zhong , Zixiang Zhou , Xiaoyue Mi , Long Hu , Yuan Zhou , Qinglin Lu , Yixue Hao , Junchi Yan

Sparse activation, which selectively activates only an input-dependent set of neurons in inference, is a useful technique to reduce the computing cost of Large Language Models (LLMs) without retraining or adaptation efforts. However,…

Computation and Language · Computer Science 2024-06-12 Jifeng Song , Kai Huang , Xiangyu Yin , Boyuan Yang , Wei Gao

Large vision-language models (LVLMs) often fail to align with human preferences, leading to issues like generating misleading content without proper visual context (also known as hallucination). A promising solution to this problem is using…

Computer Vision and Pattern Recognition · Computer Science 2025-02-03 Chenglong Wang , Yang Gan , Yifu Huo , Yongyu Mu , Murun Yang , Qiaozhi He , Tong Xiao , Chunliang Zhang , Tongran Liu , Quan Du , Di Yang , Jingbo Zhu