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Histopathology image analysis is fundamental to digital pathology, with hematoxylin and eosin (H&E) staining as the gold standard for diagnostic and prognostic assessments. While H&E imaging effectively highlights cellular and tissue…

Image and Video Processing · Electrical Eng. & Systems 2025-11-18 Yao Du , Jiaxin Zhuang , Xiaoyu Zheng , Jing Cong , Limei Guo , Chao He , Lin Luo , Xiaomeng Li

Low-field magnetic resonance imaging (MRI) offers a cost-effective alternative for medical imaging in resource-limited settings. However, its widespread adoption is hindered by two key challenges: prolonged scan times and reduced image…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Daniel Tweneboah Anyimadu , Mohammed Abdalla , Mohammed M. Abdelsamea , Ahmed Karam Eldaly

Efficient measurement of high-dimensional quantum correlations, especially spatial ones, is essential for quantum technologies, given their inherent high dimensionality and easy manipulation with basic optical elements. We propose and…

Staining is essential in cell imaging and medical diagnostics but poses significant challenges, including high cost, time consumption, labor intensity, and irreversible tissue alterations. Recent advances in deep learning have enabled…

Computer Vision and Pattern Recognition · Computer Science 2025-04-15 Ziwang Xu , Lanqing Guo , Satoshi Tsutsui , Shuyan Zhang , Alex C. Kot , Bihan Wen

Virtual stain transfer leverages computer-assisted technology to transform the histochemical staining patterns of tissue samples into other staining types. However, existing methods often lose detailed pathological information due to the…

Computer Vision and Pattern Recognition · Computer Science 2026-04-07 Haiyan Wei , Hangrui Xu , Bingxu Zhu , Yulian Geng , Aolei Liu , Wenfei Yin , Jian Liu

Semantic correspondence remains a challenging task for establishing correspondences between a pair of images with the same category or similar scenes due to the large intra-class appearance. In this paper, we introduce a novel problem…

Computer Vision and Pattern Recognition · Computer Science 2024-04-04 Hailong Jin , Huiying Li

Semantic segmentation of electron microscopy (EM) is an essential step to efficiently obtain reliable morphological statistics. Despite the great success achieved using deep convolutional neural networks (CNNs), they still produce coarse…

Computer Vision and Pattern Recognition · Computer Science 2021-01-11 Zhimin Yuan , Xiaofen Ma , Jiajin Yi , Zhengrong Luo , Jialin Peng

We present a rapid, large-field bimodal imaging platform that integrates conventional brightfield microscopy with a lensless IR imaging scanner, enabling whole-slide IR image stack acquisition in minutes. Using a dedicated deep learning…

The development of reliable imaging biomarkers for the analysis of colorectal cancer (CRC) in hematoxylin and eosin (H&E) stained histopathology images requires an accurate and reproducible classification of the main tissue components in…

Developing deep learning models to analyze histology images has been computationally challenging, as the massive size of the images causes excessive strain on all parts of the computing pipeline. This paper proposes a novel deep…

Image and Video Processing · Electrical Eng. & Systems 2021-01-13 Joseph DiPalma , Arief A. Suriawinata , Laura J. Tafe , Lorenzo Torresani , Saeed Hassanpour

Traditional staining normalization approaches, e.g. Macenko, typically rely on the choice of a single representative reference image, which may not adequately account for the diverse staining patterns of datasets collected in practical…

Image and Video Processing · Electrical Eng. & Systems 2024-06-11 Desislav Ivanov , Carlo Alberto Barbano , Marco Grangetto

Expression of human epidermal growth factor receptor 2 (HER2) is an important biomarker in breast cancer patients who can benefit from cost-effective automatic Hematoxylin and Eosin (H\&E) HER2 scoring. However, developing such scoring…

Computer Vision and Pattern Recognition · Computer Science 2024-11-11 Rawan S. Abdulsadig , Bryan M. Williams , Nikolay Burlutskiy

Spectral CT offers enhanced material discrimination over single-energy systems and enables quantitative estimation of basis material density images. Water/iodine decomposition in contrast-enhanced CT is one of the most widespread…

Medical Physics · Physics 2021-03-30 Matthew Tivnan , Grace Gang , Wenchao Cao , Nadav Shapira , Peter B. Noel , J. Webster Stayman

We present the DeepHist - a novel Deep Learning framework for augmenting a network by histogram layers and demonstrate its strength by addressing image-to-image translation problems. Specifically, given an input image and a reference color…

Image and Video Processing · Electrical Eng. & Systems 2020-05-11 Mor Avi-Aharon , Assaf Arbelle , Tammy Riklin Raviv

Breast cancer is a health problem that affects mainly the female population. An early detection increases the chances of effective treatment, improving the prognosis of the disease. In this regard, computational tools have been proposed to…

Computer Vision and Pattern Recognition · Computer Science 2022-03-01 Steve Tsham Mpinda Ataky , Alessandro Lameiras Koerich

This study evaluates the generalisation capabilities of state-of-the-art histopathology foundation models on out-of-distribution multi-stain autoimmune Immunohistochemistry datasets. We compare 13 feature extractor models, including…

Computer Vision and Pattern Recognition · Computer Science 2024-10-30 Amaya Gallagher-Syed , Elena Pontarini , Myles J. Lewis , Michael R. Barnes , Gregory Slabaugh

Blood vessels (BVs) play a critical role in the Tumor Micro-Environment (TME), potentially influencing cancer progression and treatment response. However, manually quantifying BVs in Hematoxylin and Eosin (H&E) stained images is challenging…

Image and Video Processing · Electrical Eng. & Systems 2025-01-27 Jiaqi Lv , Stefan S Antonowicz , Shan E Ahmed Raza

3D Swin Transformer (3D-ST) known for its hierarchical attention and window-based processing, excels in capturing intricate spatial relationships within images. Spatial-spectral Transformer (SST), meanwhile, specializes in modeling…

Computer Vision and Pattern Recognition · Computer Science 2024-09-27 Muhammad Ahmad , Manuel Mazzara , Salvatore Distifano

Significance: Histopathological analysis of tissues is an essential tool for grading, staging, diagnosing and resecting cancers and other malignancies. Current histopathological techniques require substantial sample processing prior to…

Medical Physics · Physics 2021-07-14 Benjamin Ecclestone , Deepak Dinakaran , Parsin Haji Reza

Accurate gland segmentation in histopathology images is essential for cancer diagnosis and prognosis. However, significant variability in Hematoxylin and Eosin (H&E) staining and tissue morphology, combined with limited annotated data,…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Ha-Hieu Pham , Nguyen Lan Vi Vu , Thanh-Huy Nguyen , Ulas Bagci , Min Xu , Trung-Nghia Le , Huy-Hieu Pham
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