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This study presents a seasonally forced cholera model that incorporates imperfect vaccination as a control strategy. The model captures the temporal dynamics of susceptible, vaccinated, infected, and recovered individuals, as well as the…

Populations and Evolution · Quantitative Biology 2025-07-15 Eric Herrison Gyamfi

In this article, we construct an age-structured model for COVID-19 with vaccination and analyze it from multiple perspectives. We derive the unique disease-free equilibrium point and the basic reproduction number $ \mathscr{R}_0 $, then we…

Populations and Evolution · Quantitative Biology 2024-07-09 Ruiyang Zhou , Fengying Wei

Early estimates of the transmission potential of emerging and re-emerging infections are increasingly used to inform public health authorities on the level of risk posed by outbreaks. Existing methods to estimate the reproduction number…

Quantitative Methods · Quantitative Biology 2016-10-10 Gerardo Chowell , Cécile Viboud , Lone Simonsen , Seyed Moghadas

Understanding dynamics of an infectious disease helps in designing appropriate strategies for containing its spread in a population. Recent mathematical models are aimed at studying dynamics of some specific types of infectious diseases. In…

Dynamical Systems · Mathematics 2015-02-05 P. Raja Sekhara Rao , M. Naresh Kumar

A simple, but ``classical``, stochastic model for epidemic spread in a finite, but large, population is studied. The progress of the epidemic can be divided into three different phases that requires different tools to analyse. Initially the…

Populations and Evolution · Quantitative Biology 2018-05-29 Åke Svensson

How to prevent the spread of human diseases is a great challenge for the scientific community and so far there are many studies in which immunization strategies have been developed. However, these kind of strategies usually do not consider…

Physics and Society · Physics 2018-08-22 M. A. Di Muro , L. G. Alvarez-Zuzek , S. Havlin , L. A. Braunstein

The immune response to a pathogen has two basic features. The first is the expansion of a few pathogen-specific cells to form a population large enough to control the pathogen. The second is the process of differentiation of cells from an…

Populations and Evolution · Quantitative Biology 2014-02-04 Sean P Stromberg , Rustom Antia , Ilya Nemenman

This paper deals with the long-term behaviour and incidence of a vaccine-preventable contact disease, under the assumption that both vaccine protection and immunity after recovery are not lifelong. The mathematical model is developed in a…

Populations and Evolution · Quantitative Biology 2024-12-11 María Jesús Lopez-Herrero , Diana Taipe

In this paper, we propose a realistic mathematical model taking into account the mutual interference among the interacting populations. This model attempts to describe the control (vaccination) function as a function of the number of…

Neural and Evolutionary Computing · Computer Science 2016-11-18 V. Sree Hari Rao , M. Naresh Kumar

Since early 2020, the world has been dealing with a raging pandemic outbreak: COVID-19. A year later, vaccines have become accessible, but in limited quantities, so that governments needed to devise a strategy to decide which part of the…

Populations and Evolution · Quantitative Biology 2022-04-13 Sander Tonkens , Paul de Klaver , Mauro Salazar

How long people live depends on their health, and how it changes with age. Individual health can be tracked by the accumulation of age-related health deficits. The fraction of age-related deficits is a simple quantitative measure of human…

Quantitative Methods · Quantitative Biology 2016-03-23 Swadhin Taneja , Arnold B. Mitnitski , Kenneth Rockwood , Andrew D. Rutenberg

Recently we have used a cellular automata model which describes the dynamics of a multi-connected network to reproduce the refractory behavior and aging effects obtained in immunization experiments performed with mice when subjected to…

Statistical Mechanics · Physics 2007-05-23 Mauro Copelli , Rita M. Zorzenon dos Santos , Daniel A. Stariolo

We study an individual-based stochastic spatial epidemic model where the number of locations and the number of individuals at each location both grow to infinity. Each individual is associated with a random infection-age dependent…

Probability · Mathematics 2025-10-21 Guodong Pang , Etienne Pardoux

Epidemics occur in all shapes and forms: infections propagating in our sparse sexual networks, rumours and diseases spreading through our much denser social interactions, or viruses circulating on the Internet. With the advent of large…

Physics and Society · Physics 2013-09-02 Laurent Hébert-Dufresne , Antoine Allard , Jean-Gabriel Young , Louis J. Dubé

Mathematical and computational modeling approaches are increasingly used as quantitative tools in the analysis and forecasting of infectious disease epidemics. The growing need for realism in addressing complex public health questions is…

An interesting inference drawn by some Covid-19 epidemiological models is that there exists a proportion of the population who are not susceptible to infection -- even at the start of the current pandemic. This paper introduces a model of…

Quantitative Methods · Quantitative Biology 2020-09-18 Thomas Parr , Anjali Bhat , Peter Zeidman , Aimee Goel , Alexander J. Billig , Rosalyn Moran , Karl J. Friston

Spreading processes represent a very efficient tool to investigate the structural properties of networks and the relative importance of their constituents, and have been widely used to this aim in static networks. Here we consider simple…

Physics and Society · Physics 2013-09-11 Michele Starnini , Anna Machens , Ciro Cattuto , Alain Barrat , Romualdo Pastor Satorras

In temperate regions, respiratory virus epidemics recur on a yearly basis, primarily during the winter season. This is believed to be induced by seasonal forcing, where the rate at which the virus can be transmitted varies cyclically across…

Populations and Evolution · Quantitative Biology 2026-04-28 Ruarai J Tobin , James M McCaw , Freya M Shearer

The topic of finding effective strategy to halt virus in complex network is of current interest. We propose an immunization strategy for seasonal epidemics that occur periodically. Based on the local information of the infection status from…

Applications · Statistics 2015-06-22 Shu Yan , Shaoting Tang , Sen Pei , Shijin Jiang , Zhiming Zheng

In this paper we propose a macro-dynamic age-structured set-up for the analysis of epidemics/economic dynamics in continuous time. The resulting optimal control problem is reformulated in an infinite dimensional Hilbert space framework…

Theoretical Economics · Economics 2020-08-18 Giorgio Fabbri , Fausto Gozzi , Giovanni Zanco
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