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We study a stochastic epidemic model with multiple patches (locations), where individuals in each patch are categorized into three compartments, Susceptible, Infected and Recovered/Removed, and may migrate from one patch to another in any…

Probability · Mathematics 2023-08-21 Guodong Pang , Etienne Pardoux

System dynamics and agent based simulation models can both be used to model and understand interactions of entities within a population. Our modeling work presented here is concerned with understanding the suitability of the different types…

Computational Engineering, Finance, and Science · Computer Science 2013-06-27 Grazziela P. Figueredo , Uwe Aickelin

Compartmental models have long served as important tools in mathematical epidemiology, with their usefulness highlighted by the recent COVID-19 pandemic. However, most of the classical models fail to account for certain features of this…

Dynamical Systems · Mathematics 2023-08-21 Monique Chyba , Taylor Klotz , Yuriy Mileyko , Corey Shanbrom

This is an epidemiological SIRV model based study that is designed to analyze the impact of vaccination in containing infection spread, in a 4-tiered population compartment comprised of susceptible, infected, recovered and vaccinated…

Populations and Evolution · Quantitative Biology 2018-11-14 Ewa Grela , Michael Stich , Amit K Chattopadhyay

We analyse the infection-age-dependent SIR model from a numerical point of view. First, we present an algorithm for calculating the solution the infection-age-structured SIR model without demography of the background host. Second, we…

Populations and Evolution · Quantitative Biology 2020-06-29 Ralph Brinks , Annika Hoyer

The success of an infectious disease to invade a population is strongly controlled by the population's specific connectivity structure. Here a network model is presented as an aid in understanding the role of social behavior and…

Cellular Automata and Lattice Gases · Physics 2007-07-10 Anna Litvak-Hinenzon , Lewi Stone

Age at infection is often an important factor in epidemic dynamics. In this paper a disease transmission model of SIS type with age dependent infection on a heterogeneous network is discussed. The model allows the infectious rate and the…

Dynamical Systems · Mathematics 2018-06-19 Shanshan Chen , Michael Small , Yizhou Tao , Xinchu Fu

Voluntary vaccination is essential to protect oneself from infection and suppress the spread of infectious diseases. Voluntary vaccination behavior is influenced by factors such as age and interaction patterns. Differences in health…

Physics and Society · Physics 2024-12-11 Yanyi Nie , Tao Lin , Yanbing Liu , Wei Wang

Motivated by the increasing number of COVID-19 cases that have been observed in many countries after the vaccination and relaxation of non-pharmaceutical interventions, we propose a mathematical model on time-varying networks for the spread…

Dynamical Systems · Mathematics 2022-03-09 Kathinka Frieswijk , Lorenzo Zino , Ming Cao

In the face of serious infectious diseases, governments endeavour to implement containment measures such as public vaccination at a macroscopic level. Meanwhile, individuals tend to protect themselves by avoiding contacts with infections at…

Physics and Society · Physics 2016-10-20 Xiao-Long Peng , Xin-Jian Xu , Michael Small , Xinchu Fu , Zhen Jin

Qatar has undergone distinct waves of COVID-19 infections, compounded by the emergence of variants, posing additional complexities. This research uniquely delves into the varied efficacy of existing vaccines and the pivotal role of…

Applications · Statistics 2023-12-29 Elizabeth Amona , Indranil Sahoo , Edward Boone , Ryad Ghanam

When an infectious disease propagates throughout society, the incidence function may rise at first due to an increase in pathogenicity and then decrease due to inhibitory effects until it reaches saturation. Effective vaccination and…

Dynamical Systems · Mathematics 2023-07-11 Sushil Pathak , G. Shirisha , K. Venkata Ratnam

We introduce an epidemic model with varying infectivity and general exposed and infectious periods, where the infectivity of each individual is a random function of the elapsed time since infection, those function being i.i.d. for the…

Probability · Mathematics 2021-06-01 Raphael Forien , Guodong Pang , Etienne Pardoux

SIRS models capture transmission dynamics of infectious diseases for which immunity is not lifelong. Extending these models by a W compartment for individuals with waning immunity, the boosting of the immune system upon repeated exposure…

Populations and Evolution · Quantitative Biology 2022-01-19 Richmond Opoku-Sarkodie , Ferenc A. Bartha , Mónika Polner , Gergely Röst

In diseases with long-term immunity, vaccination is known to increase the average age at infection as a result of the decrease in the pathogen circulation. This implies that a vaccination campaign can have negative effects when a disease is…

Populations and Evolution · Quantitative Biology 2024-06-04 Fabio A. C. C. Chalub , Paulo Doutor , Paula Patrício , Maria do Céu Soares

Viral infections trigger complex immune responses with heterogeneous outcomes shaped by nonlinear feedbacks. An ordinary differential equation model is developed to investigate immune response dynamics during viral infection, incorporating…

Quantitative Methods · Quantitative Biology 2025-10-08 Xiaoxin Wang , Kai Kang , Leyi Zhang , Changjing Zhuge

The spread of infectious disease is strongly influenced by social dynamics. In addition to infection risk, individuals vaccination decisions depend on prevailing social behavior: high infection levels and widespread vaccination can increase…

Populations and Evolution · Quantitative Biology 2026-04-17 Xinxuan Wang , Youngmin Park , Bryce Morsky

We study how the interplay between the memory immune response and pathogen mutation affects epidemic dynamics in two related models. The first explicitly models pathogen mutation and individual memory immune responses, with contacted…

Chaotic Dynamics · Physics 2009-11-07 Michelle Girvan , Duncan S. Callaway , M. E. J. Newman , Steven H. Strogatz

Susceptible-Infected-Recovered (SIR) models have been used for decades to understand epidemic outbreak dynamics. We develop an SIR model specifically designed to study the effects of population behavior with respect to health and…

Populations and Evolution · Quantitative Biology 2023-08-03 Jasmin Nunuvero , Angelique Santiago , Moshe Cohen , Anca Radulescu

The shape of an epidemic wave in simple epidemic models applies to a homogeneous distribution of infected people in the population. In large inhomogeneous systems, at country-scale for instance, the wave shape is similar except for the…

Chemical Physics · Physics 2022-11-21 L. Vanel