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Infection by distinct Dengue virus serotypes and host immunity are intricately linked. In particular, certain levels of cross-reactive antibodies in the host may actually enhance infection severity leading to Dengue hemorrhagic fever (DHF).…
Dengue fever is a virulent disease spreading over 100 tropical and subtropical countries in Africa, the Americas, and Asia. This arboviral disease affects around 400 million people globally, severely distressing the healthcare systems. The…
We consider a predator-prey population model with prey gathering together for defense purposes. A transmissible unrecoverable disease affects the prey. We characterize the system behavior, establishing that ultimately either only the…
Dengue control in India is a challenging task due to complex healthcare settings. In yesteryears, an amplification of dengue infections in India posed the need for introspection of existing dengue control policies. Prior understanding of…
We investigate a time-dependent spatial vector-host epidemic model with non-coincident domains for the vector and host populations. The host population resides in small non-overlapping sub-regions, while the vector population resides…
Viruses display striking diversity in structure, transmission mode, immune interaction, and evolutionary behavior. Despite this diversity, viral strategies are not unconstrained. Here we present a unifying framework that treats viral…
Dengue is a viral infection that can produce a severe fever and symptoms that may require hospitalization. It is transmitted between humans by the urban-adapted, day-biting Aedes mosquitoes and is therefore a particular problem in towns and…
A four dimensional ecoepidemiological model consisting of susceptible prey, infected prey, vaccinated prey and predator is formulated and analyzed in the present work. The functional response is assumed to be of Lotka-Volterra type. We…
Human pathogens transmitted through environmental pathways are subject to stress and pressures outside of the host. These pressures may cause pathogen pathovars to diverge in their environmental persistence and their infectivity on an…
Over 50% of the world population is at risk of mosquito-borne diseases. Female Ae. aegypti mosquito species transmit Zika, Dengue, and Chikungunya. The spread of these diseases correlate positively with the vector population, and this…
Arboviral infections, especially dengue, continue to cause significant health burden in their endemic regions. One of the strategies to tackle these infections is to replace the main vector agent, Ae. aegypti, with the ones incapable of…
Many pathogens spread primarily via direct contact between infected and susceptible hosts. Thus, the patterns of contacts or contact network of a population fundamentally shapes the course of epidemics. While there is a robust and growing…
Dengue fever poses a persistent public health challenge in rapidly urbanizing Indian cities such as Ahmedabad, where spatial heterogeneity and seasonal variability complicate forecasting and control. In this study, we develop a data-driven…
Several stains of the intracellular parasitic bacterium Wolbachia limit severely the competence of the mosquitoes Aedes aegypti as a vector of dengue fever and possibly other arboviroses. For this reason, the release of mosquitoes infected…
We propose and analyze an epidemiological model for vector borne diseases that integrates a multi-stage vector population and several host sub-populations which may be characterized by a variety of compartmental model types: subpopulations…
We present an application of optimal control theory to Dengue epidemics. This epidemiologic disease is an important theme in tropical countries due to the growing number of infected individuals. The dynamic model is described by a set of…
Despite being similar in structure, functioning, and size viral pathogens enjoy very different mostly well-defined ways of life. They occupy their hosts for a few days (influenza), for a few weeks (measles), or even lifelong (HCV), which…
Rapidly mutating pathogens may be able to persist in the population and reach an endemic equilibrium by escaping hosts' acquired immunity. For such diseases, multiple biological, environmental and population-level mechanisms determine the…
Dengue is a viral vector-borne infectious disease that affects many countries worldwide, infecting around 390 million people per year. The main outbreaks occur in subtropical and tropical countries. We study here the influence of climate on…
Dengue fever is a disease which is transmitted and caused by Aedes Aegypti mosquitos. Dengue has become a serious health issue in all over the world especially in those countries who are situated in tropical or subtropical regions because…