Related papers: Improving Gene Trees without more data
Period estimation is an important task in the classification of many variable astrophysical objects. Here we present GRAPE: Genetic Routine for Astronomical Period Estimation, a genetic algorithm optimised for the processing of survey data…
Tree shape statistics quantify some aspect of the shape of a phylogenetic tree. They are commonly used to compare reconstructed trees to evolutionary models and to find evidence of tree reconstruction bias. Historically, to find a useful…
This work develops formal statistical inference procedures for machine learning ensemble methods. Ensemble methods based on bootstrapping, such as bagging and random forests, have improved the predictive accuracy of individual trees, but…
Given a gene tree and a species tree, ancestral configurations represent the combinatorially distinct sets of gene lineages that can reach a given node of the species tree. They have been introduced as a data structure for use in the…
With the abundance of industrial datasets, imbalanced classification has become a common problem in several application domains. Oversampling is an effective method to solve imbalanced classification. One of the main challenges of the…
2-colored best match graphs (2-BMGs) form a subclass of sink-free bi-transitive graphs that appears in phylogenetic combinatorics. There, 2-BMGs describe evolutionarily most closely related genes between a pair of species. They are…
A major task of evolutionary biology is the reconstruction of phylogenetic trees from molecular data. The evolutionary model is given by a Markov chain on a tree. Given samples from the leaves of the Markov chain, the goal is to reconstruct…
Tree-based models underpin many modern semantic search engines and recommender systems due to their sub-linear inference times. In industrial applications, these models operate at extreme scales, where every bit of performance is critical.…
*Context: The optimisation of new multiplex spectrographs (resolution, wavelength range,...), their associated surveys (choice of setup), or their parameterisation pipelines require methods that estimate which wavelengths contain useful…
We present the Network-based Biased Tree Ensembles (NetBiTE) method for drug sensitivity prediction and drug sensitivity biomarker identification in cancer using a combination of prior knowledge and gene expression data. Our devised method…
Traditional decision tree models, which rely exclusively on numerical variables, often face challenges in handling high-dimensional data and are limited in their ability to incorporate textual information effectively. To address these…
The architecture of eukaryotic coding genes allows the production of several different protein isoforms by genes. Current gene phylogeny reconstruction methods make use of a single protein product per gene, ignoring information on…
While fine-tuning pre-trained networks has become a popular way to train image segmentation models, such backbone networks for image segmentation are frequently pre-trained using image classification source datasets, e.g., ImageNet. Though…
We theorize that phylogenetic profiles provide a quantitative method that can relate the structural and functional properties of proteins, as well as their evolutionary relationships. A key feature of phylogenetic profiles is the…
Decision trees are commonly used predictive models due to their flexibility and interpretability. This paper is directed at quantifying the uncertainty of decision tree predictions by employing a Bayesian inference approach. This is…
Manifold learning techniques play a pivotal role in machine learning by revealing lower-dimensional embeddings within high-dimensional data, thus enhancing both the efficiency and interpretability of data analysis by transforming the data…
Random splitting of datasets in image segmentation often leads to unrepresentative test sets, resulting in biased evaluations and poor model generalization. While stratified sampling has proven effective for addressing label distribution…
Accurate streamflow prediction largely relies on historical meteorological records and streamflow measurements. For many regions, however, such data are only scarcely available. Facing this problem, many studies simply trained their machine…
When data have a hierarchical structure, such as students nested within classrooms, ignoring dependencies between observations can compromise the validity of imputation procedures. Standard tree-based imputation methods implicitly assume…
In this research, we investigate the possibility of applying a search strategy to genetic algorithms to explore the entire genetic tree structure. Several methods aid in performing tree searches; however, simpler algorithms such as…