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Depression commonly co-occurs with neurodegenerative disorders like Multiple Sclerosis (MS), yet the potential of speech-based Artificial Intelligence for detecting depression in such contexts remains unexplored. This study examines the…

Computation and Language · Computer Science 2025-08-26 Monica Gonzalez-Machorro , Uwe Reichel , Pascal Hecker , Helly Hammer , Hesam Sagha , Florian Eyben , Robert Hoepner , Björn W. Schuller

Schizophrenia (SZ) is a serious mental disorder that could seriously affect the patient's quality of life. In recent years, detection of SZ based on deep learning (DL) using electroencephalogram (EEG) has received increasing attention. In…

Neurons and Cognition · Quantitative Biology 2022-07-12 Yihan Wu , Min Xia , Xiuzhu Wang , Yangsong Zhang

Autism spectrum disorder (ASD) can be defined as a neurodevelopmental disorder that affects how children interact, communicate and socialize with others. This disorder can occur in a broad spectrum of symptoms, with varying effects and…

Machine Learning · Computer Science 2021-10-08 Vikram Ramesh , Rida Assaf

Autism Spectrum Disorder (ASD) is a developmental disorder that often impairs a child's normal development of the brain. According to CDC, it is estimated that 1 in 6 children in the US suffer from development disorders, and 1 in 68…

Signal Processing · Electrical Eng. & Systems 2019-07-03 Yasith Jayawardana , Mark Jaime , Sashi Thapaliya , Sampath Jayarathna

During psychiatric assessment, clinicians observe not only what patients report, but important nonverbal signs such as tone, speech rate, fluency, responsiveness, and body language. Weighing and integrating these different information…

Machine Learning · Computer Science 2025-12-19 Agnes Norbury , George Fairs , Alexandra L. Georgescu , Matthew M. Nour , Emilia Molimpakis , Stefano Goria

Multimodal depression classification has gained immense popularity over the recent years. We develop a multimodal depression classification system using articulatory coordination features extracted from vocal tract variables and text…

Audio and Speech Processing · Electrical Eng. & Systems 2022-02-15 Nadee Seneviratne , Carol Espy-Wilson

Key features of mental illnesses are reflected in speech. Our research focuses on designing a multimodal deep learning structure that automatically extracts salient features from recorded speech samples for predicting various mental…

Machine Learning · Computer Science 2020-04-15 Habibeh Naderi , Behrouz Haji Soleimani , Stan Matwin

Mental disorders such as Autism Spectrum Disorders (ASD) are heterogeneous disorders that are notoriously difficult to diagnose, especially in children. The current psychiatric diagnostic process is based purely on the behavioural…

Machine Learning · Computer Science 2019-04-17 Taban Eslami , Vahid Mirjalili , Alvis Fong , Angela Laird , Fahad Saeed

Formal thought disorder (FTD), a hallmark of schizophrenia spectrum disorders, manifests as incoherent speech and poses challenges for clinical assessment. Traditional clinical rating scales, though validated, are resource-intensive and…

Depression is a common mental disorder. Automatic depression detection tools using speech, enabled by machine learning, help early screening of depression. This paper addresses two limitations that may hinder the clinical implementations of…

Computation and Language · Computer Science 2023-10-09 Qingkun Deng , Saturnino Luz , Sofia de la Fuente Garcia

The present review presents multiple techniques in which ocular assessments may serve as a noninvasive approach for the early diagnoses of various cognitive and psychiatric disorders, such as Alzheimer's disease (AD), autism spectrum…

Neurons and Cognition · Quantitative Biology 2020-04-06 Xiaotao Li , Xuejing Chen , Fangfang Fan , Li Ning , Kangguang Lin , Zan Chen , Zhenyun Qin , Albert S. Yeung , Liping Wang , Xiaojian Li , Kwok-Fai So

Stuttering is a complex speech disorder that can be identified by repetitions, prolongations of sounds, syllables or words, and blocks while speaking. Severity assessment is usually done by a speech therapist. While attempts at automated…

Quantitative Methods · Quantitative Biology 2020-06-17 Sebastian P. Bayerl , Florian Hönig , Joelle Reister , Korbinian Riedhammer

Autism Spectrum Disorder (ASD) is a lifelong condition that significantly influencing an individual's communication abilities and their social interactions. Early diagnosis and intervention are critical due to the profound impact of ASD's…

Computation and Language · Computer Science 2024-09-04 Jihyun Mun , Sunhee Kim , Minhwa Chung

Speech and language technologies offer valuable opportunities for supporting mental health assessment through objective and interpretable cues. We present a systematic feature-based analysis framework leveraging perceptually grounded…

Artificial Intelligence · Computer Science 2026-05-28 Vassilis Lyberatos , Edmund G. Dervakos , Eleni Adamidi , Athanasios Voulodimos , Giorgos Stamou

Early detection of exacerbations in asthma and chronic obstructive pulmonary disease (COPD) is important for timely intervention. Speech has emerged as a promising tool for continuous, non-invasive respiratory disease monitoring. However,…

Sound · Computer Science 2026-05-19 Yuyang Yan , Sami O. Simons , Visara Urovi

Automatic detection of Alzheimer's dementia by speech processing is enhanced when features of both the acoustic waveform and the content are extracted. Audio and text transcription have been widely used in health-related tasks, as spectral…

Audio and Speech Processing · Electrical Eng. & Systems 2020-08-12 Edward L. Campbell , Laura Docío-Fernández , Javier Jiménez Raboso , Carmen García-Mateo

Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the leading cause of dementia, affecting memory, reasoning, communication, and daily functioning. Early diagnosis is particularly important, as timely intervention may…

Sound · Computer Science 2026-05-26 Loukas Ilias , Dimitris Askounis

Depression manifests through a diverse set of symptoms such as sleep disturbance, loss of interest, and concentration difficulties. However, most existing works treat depression prediction either as a binary label or an overall severity…

Computation and Language · Computer Science 2026-02-18 Chaithra Nerella , Chiranjeevi Yarra

Schizophrenia is a severe, currently incurable, relatively common mental condition. Its symptoms are complex and widespread. It structurally and functionally affects cortical and subcortical regions involved in cognitive, emotional and…

Quantitative Methods · Quantitative Biology 2007-09-05 Anca R. Radulescu

Timely and accurate assessment of cognitive impairment remains a major unmet need. Speech biomarkers offer a scalable, non-invasive, cost-effective solution for automated screening. However, the clinical utility of machine learning (ML)…