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Currently, every 1 in 54 children have been diagnosed with Autism Spectrum Disorder (ASD), which is 178% higher than it was in 2000. An early diagnosis and treatment can significantly increase the chances of going off the spectrum and…

Computer Vision and Pattern Recognition · Computer Science 2021-04-05 Spencer He , Ryan Liu

Dysarthria is a neurological speech disorder that can significantly impact affected individuals' communication abilities and overall quality of life. The accurate and objective classification of dysarthria and the determination of its…

Speech is a critical biomarker for Huntington Disease (HD), with changes in speech increasing in severity as the disease progresses. Speech analyses are currently conducted using either transcriptions created manually by trained…

Audio and Speech Processing · Electrical Eng. & Systems 2020-08-11 Matthew Perez , Wenyu Jin , Duc Le , Noelle Carlozzi , Praveen Dayalu , Angela Roberts , Emily Mower Provost

Autism Spectrum Disorder (ASD) is a complex neuro-developmental challenge, presenting a spectrum of difficulties in social interaction, communication, and the expression of repetitive behaviors in different situations. This increasing…

Machine Learning · Computer Science 2025-06-16 Mohd Mujtaba Akhtar , Girish , Muskaan Singh , Orchid Chetia Phukan

Autism Spectrum Disorder(ASD) is a set of neurodevelopmental conditions that affect patients' social abilities. In recent years, many studies have employed deep learning to diagnose this brain dysfunction through functional MRI (fMRI).…

Image and Video Processing · Electrical Eng. & Systems 2021-10-26 Li Pan , Jundong Liu , Mingqin Shi , Chi Wah Wong , Kei Hang Katie Chan

This paper presents our submission to the PROCESS Challenge 2025, focusing on spontaneous speech analysis for early dementia detection. For the three-class classification task (Healthy Control, Mild Cognitive Impairment, and Dementia), we…

Audio and Speech Processing · Electrical Eng. & Systems 2025-05-28 Yin-Long Liu , Yuanchao Li , Rui Feng , Liu He , Jia-Xin Chen , Yi-Ming Wang , Yu-Ang Chen , Yan-Han Peng , Jia-Hong Yuan , Zhen-Hua Ling

Dementia is a progressive cognitive syndrome with Alzheimer's disease (AD) as the leading cause. Conversation-based AD detection offers a cost-effective alternative to clinical methods, as language dysfunction is an early biomarker of AD.…

Computation and Language · Computer Science 2025-02-27 Arezo Shakeri , Mina Farmanbar , Krisztian Balog

Autism spectrum disorder (ASD) has been associated with structural alterations across cortical and subcortical regions. Quantitative neuroimaging enables large-scale analysis of these neuroanatomical patterns. This project used structural…

Neurons and Cognition · Quantitative Biology 2025-12-30 Ashley Chen

In this work, we present a novel perspective on cognitive impairment classification from speech by integrating speech foundation models that explicitly recognize speech dialects. Our motivation is based on the observation that individuals…

Sound · Computer Science 2026-01-14 Tiantian Feng , Anfeng Xu , Jinkook Lee , Shrikanth Narayanan

Dementia is a neurodegenerative disease that causes gradual cognitive impairment, which is very common in the world and undergoes a lot of research every year to prevent and cure it. It severely impacts the patient's ability to remember…

In this work we explore how language models can be employed to analyze language and discriminate between mentally impaired and healthy subjects through the perplexity metric. Perplexity was originally conceived as an information-theoretic…

Computation and Language · Computer Science 2023-02-03 Davide Colla , Matteo Delsanto , Marco Agosto , Benedetto Vitiello , Daniele Paolo Radicioni

Resting state electroencephalogram (EEG) abnormalities in clinically high-risk individuals (CHR), clinically stable first-episode patients with schizophrenia (FES), healthy controls (HC) suggest alterations in neural oscillatory activity.…

Signal Processing · Electrical Eng. & Systems 2018-01-18 Haichun Liu , TianHong Zhang , Yumeng Ye , Changchun Pan , Genke Yang , JiJun Wang , Robert C. Qiu

With the availability of voice-enabled devices such as smart phones, mental health disorders could be detected and treated earlier, particularly post-pandemic. The current methods involve extracting features directly from audio signals. In…

Machine Learning · Computer Science 2022-05-17 Nasser Ghadiri , Rasoul Samani , Fahime Shahrokh

Autism Spectrum Disorder (ASD) is one neuro developmental disorder that is now widespread in the world. ASD persists throughout the life of an individual, impacting the way they behave and communicate, resulting to notable deficits…

Computer Vision and Pattern Recognition · Computer Science 2023-03-23 Godfrin Ismail , Kenneth Chesoli , Golda Moni , Kinyua Gikunda

Empirical studies over the past two decades have supported the hypothesis that schizophrenia is characterized by altered connectivity patterns in functional brain networks. These alterations have been proposed as genetically-mediated…

Neurons and Cognition · Quantitative Biology 2013-06-28 Felix Siebenhuhner , Shennan A. Weiss , Richard Coppola , Daniel R. Weinberger , Danielle S. Bassett

We propose a model for diagnosing Autism spectrum disorder (ASD) using multimodal magnetic resonance imaging (MRI) data. Our approach integrates brain connectivity data from diffusion tensor imaging (DTI) and functional MRI (fMRI),…

Neurons and Cognition · Quantitative Biology 2024-10-10 Lu Wei , Yi Huang , Guosheng Yin , Fode Zhang , Manxue Zhang , Bin Liu

Speech-based depression detection has shown promise as an objective diagnostic tool, yet the cross-linguistic robustness of acoustic markers and their neurobiological underpinnings remain underexplored. This study extends Cross-Data…

Audio and Speech Processing · Electrical Eng. & Systems 2026-04-07 Fuxiang Tao , Dongwei Li , Shuning Tang , Xuri Ge , Wei Ma , Anna Esposito , Alessandro Vinciarelli

This literature review involves the use of AI communication facilitators to detect mood disorders such as bipolar disorder, a psychiatric condition in which patients experience drastic mood shifts. Due to the ill-defined nature of the…

Human-Computer Interaction · Computer Science 2023-04-18 Trisha Guttal

Although automatic emotion recognition (AER) has recently drawn significant research interest, most current AER studies use manually segmented utterances, which are usually unavailable for dialogue systems. This paper proposes integrating…

Audio and Speech Processing · Electrical Eng. & Systems 2023-08-15 Wen Wu , Chao Zhang , Philip C. Woodland

Objective: Schizophrenia seriously affects the quality of life. To date, both simple (linear discriminant analysis) and complex (deep neural network) machine learning methods have been utilized to identify schizophrenia based on functional…

Machine Learning · Computer Science 2021-05-11 Tian Wang , Anastasios Bezerianos , Andrzej Cichocki , Junhua Li
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