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For most organisms with viscous population structure, spatially localized growth drives the invasive advance of a favorable mutation. We model a two-allele competition where recurrent mutation introduces a genotype with a rate of local…

Populations and Evolution · Quantitative Biology 2007-05-23 Lauren O'Malley , James Basham , Joseph A. Yasi , G. Korniss , Andrew Allstadt , Tom Caraco

We present a statistical analysis of biological evolution processes. Specifically, we study the stochastic replication-mutation-death model where the population of a species may grow or shrink by birth or death, respectively, and…

Populations and Evolution · Quantitative Biology 2007-05-23 E. Ben-Naim , P. L. Krapivsky

We investigate the evolutionary dynamics in directed and/or weighted networks. We study the fixation probability of a mutant in finite populations in stochastic voter-type dynamics for several update rules. The fixation probability is…

Physics and Society · Physics 2009-03-12 Naoki Masuda , Hisashi Ohtsuki

The evolution of antimicrobial resistance generally occurs in an environment where antimicrobial concentration is variable, which has dramatic consequences on the microorganisms' fitness landscape, and thus on the evolution of resistance.…

Biological Physics · Physics 2018-10-23 Loïc Marrec , Anne-Florence Bitbol

We consider a trait-structured population subject to mutation, birth and competition of logistic type, where the number of coexisting types may fluctuate. Applying a limit of rare mutations to this population while keeping the population…

Probability · Mathematics 2011-12-05 Nicolas Champagnat , Amaury Lambert

A population genetics model based on a multitype branching process, or equivalently a Galton-Watson branching process for multiple alleles, is pre- sented. The diffusion limit forward Kolmogorov equation is derived for the case of neutral…

Populations and Evolution · Quantitative Biology 2018-02-21 Conrad J. Burden , Yi Wei

I study a population model in which the reproduction rate lambda is inherited with mutation, favoring fast reproducers in the short term, but conflicting with a process that eliminates agglomerations of individuals. The model is a variant…

Statistical Mechanics · Physics 2021-06-02 Ronald Dickman

I discuss the so-called stochastic individual based model of adaptive dynamics and in particular how different scaling limits can be obtained by taking limits of large populations, small mutation rate, and small effect of single mutations…

Populations and Evolution · Quantitative Biology 2021-07-06 Anton Bovier

Languages and genes are both transmitted from generation to generation, with opportunity for differential reproduction and survivorship of forms. Here we apply a rigorous inference framework, drawn from population genetics, to distinguish…

Populations and Evolution · Quantitative Biology 2017-11-07 Christopher A. Ahern , Mitchell G. Newberry , Robin Clark , Joshua B. Plotkin

It has been a puzzling question why some organisms reproduce sexually. Fisher and Muller hypothesized that reproducing by sex can speed up the evolution. They explained that in the sexual reproduction, recombination can combine beneficial…

Probability · Mathematics 2021-04-19 Nantawat Udomchatpitak

In evolutionary game theory, an important measure of a mutant trait (strategy) is its ability to invade and take over an otherwise-monomorphic population. Typically, one quantifies the success of a mutant strategy via the probability that a…

Populations and Evolution · Quantitative Biology 2016-04-12 Alex McAvoy , Christoph Hauert

Pervasive natural selection can strongly influence observed patterns of genetic variation, but these effects remain poorly understood when multiple selected variants segregate in nearby regions of the genome. Classical population genetics…

Populations and Evolution · Quantitative Biology 2013-06-06 Benjamin H. Good , Aleksandra M. Walczak , Richard A. Neher , Michael M. Desai

Many life-history traits, like the age at maturity or adult longevity, are important determinants of the generation time. For instance, semelparous species whose adults reproduce once and die have shorter generation times than iteroparous…

Populations and Evolution · Quantitative Biology 2016-04-22 Mélissa Verin , Salomé Bourg , Frédéric Menu , Etienne Rajon

The influence of migration on the stochastic dynamics of subdivided populations is still an open issue in various evolutionary models. We develop here a self-consistent mean-field-like method in order to determine the effects of migration…

Statistical Mechanics · Physics 2014-04-10 Pierangelo Lombardo , Andrea Gambassi , Luca Dall'Asta

Although mutations drive the evolutionary process, the rates at which the mutations occur are themselves subject to evolutionary forces. Our purpose here is to understand the role of selection and random genetic drift in the evolution of…

Populations and Evolution · Quantitative Biology 2016-10-27 Ananthu James , Kavita Jain

The drift-barrier hypothesis states that random genetic drift constrains the refinement of a phenotype under natural selection. The influence of effective population size and the genome-wide deleterious mutation rate were studied…

Populations and Evolution · Quantitative Biology 2024-07-25 Luis A. La Rocca , Konrad Gerischer , Anton Bovier , Peter M. Krawitz

Adaptive dynamics so far has been put on a rigorous footing only for clonal inheritance. We extend this to sexually reproducing diploids, although admittedly still under the restriction of an unstructured population with Lotka-Volterra-like…

Probability · Mathematics 2011-11-29 Pierre Collet , Sylvie Méléard , J. A. J. Metz

Evolution has fascinated quantitative and physical scientists for decades: how can the random process of mutation, recombination, and duplication of genetic information generate the diversity of life? What determines the rate of evolution?…

Populations and Evolution · Quantitative Biology 2018-04-23 Richard A. Neher , Aleksandra M. Walczak

McNamara and Dall (2011) identified novel relationships between the abundance of a species in different environments, the temporal properties of environmental change, and selection for or against dispersal. Here, the mathematics underlying…

Populations and Evolution · Quantitative Biology 2013-02-04 Lee Altenberg

Theories to explain the prevalence of sex and recombination have long been a central theme of evolutionary biology. Yet despite decades of attention dedicated to the evolution of sex and recombination, the widespread pattern of…

Populations and Evolution · Quantitative Biology 2011-12-12 Yaniv Brandvain , Graham Coop