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We present a dual-resolution molecular dynamics (MD) simulation of liquid water employing a recently introduced Adaptive Resolution Scheme (AdResS). The spatially adaptive molecular resolution procedure allows for changing from a…

Soft Condensed Matter · Physics 2011-11-10 Silvina Matysiak , Cecilia Clementi , Matej Praprotnik , Kurt Kremer , Luigi Delle Site

Diffusion Models (DMs) have impressive capabilities among generation models, but are limited to slower inference speeds and higher computational costs. Previous works utilize one-shot structure pruning to derive lightweight DMs from…

Machine Learning · Computer Science 2025-01-17 Ben Wan , Tianyi Zheng , Zhaoyu Chen , Yuxiao Wang , Jia Wang

Numerical simulation of fluids plays an essential role in modeling many physical phenomena, such as weather, climate, aerodynamics and plasma physics. Fluids are well described by the Navier-Stokes equations, but solving these equations at…

Fluid Dynamics · Physics 2022-04-27 Dmitrii Kochkov , Jamie A. Smith , Ayya Alieva , Qing Wang , Michael P. Brenner , Stephan Hoyer

Mass spectrometry is a powerful and widely used tool for identifying molecular structures due to its sensitivity and ability to profile complex samples. However, translating spectra into full molecular structures is a difficult,…

Machine Learning · Computer Science 2026-03-13 Ghaith Mqawass , Tuan Le , Fabian Theis , Djork-Arné Clevert

An alternative to the fully implicit or monolithic methods used for the solution of the coupling of fluid flow and deformation in porous media is a sequential approach in which the fully coupled system is broken into subproblems (flow and…

Numerical Analysis · Mathematics 2025-12-23 Xiaozhe Hu , Francisco J. Gaspar , Carmen Rodrigo

Diffusion models create data from noise by inverting the forward paths of data towards noise and have emerged as a powerful generative modeling technique for high-dimensional, perceptual data such as images and videos. Rectified flow is a…

We describe a novel approach to statistical learning from particles tracked while moving in a random environment. The problem consists in inferring properties of the environment from recorded snapshots. We consider here the case of a fluid…

Information Theory · Computer Science 2008-06-09 Michael Chertkov , Lukas Kroc , Massimo Vergassola

Functional connectivity estimates are highly sensitive to analysis choices and can be dominated by noise when the number of sampled time points is small relative to network dimensionality. This issue is particularly acute in fMRI, where…

Disordered Systems and Neural Networks · Physics 2026-02-10 Izaro Fernandez-Iriondo , Antonio Jimenez-Marin , Jesus Cortes , Pablo Villegas

Inferring physical fields from sparse observations while strictly satisfying partial differential equations (PDEs) is a fundamental challenge in computational physics. Recently, deep generative models offer powerful data-driven priors for…

Machine Learning · Computer Science 2026-01-29 Zichao Yu , Ming Li , Wenyi Zhang , Difan Zou , Weiguo Gao

We propose a novel framework for analyzing the dynamics of distribution shift in real-world systems that captures the feedback loop between learning algorithms and the distributions on which they are deployed. Prior work largely models…

Machine Learning · Computer Science 2023-10-31 Lauren Conger , Franca Hoffmann , Eric Mazumdar , Lillian Ratliff

Data heterogeneity hinders clinical deployment of medical image analysis models, and generative data augmentation helps mitigate this issue. However, recent diffusion-based methods that synthesize image-mask pairs often ignore distribution…

Image and Video Processing · Electrical Eng. & Systems 2026-04-06 Jie Yang , Ziqi Ye , Aihua Ke , Jian Luo , Bo Cai , Xiaosong Wang

We present a ``coarse molecular dynamics'' approach and apply it to studying the kinetics and thermodynamics of a peptide fragment dissolved in water. Short bursts of appropriately initialized simulations are used to infer the deterministic…

Chemical Physics · Physics 2009-11-07 Gerhard Hummer , Ioannis G. Kevrekidis

Developing physics-based models for molecular simulation requires fitting many unknown parameters to diverse experimental datasets. Traditionally, this process is piecemeal and difficult to reproduce, leading to a fragmented landscape of…

Biological Physics · Physics 2025-04-10 Ryan K. Krueger , Megan C. Engel , Ryan Hausen , Michael P. Brenner

Separated flows past complex geometries are modelled by discrete vortex techniques. The flows are assumed to be rotational and inviscid, and a new technique is described to determine the streamfunctions for linear shear profiles. The…

chao-dyn · Physics 2007-05-23 P. Franzese , L. Zannetti

Atomistic or ab-initio molecular dynamics simulations are widely used to predict thermodynamics and kinetics and relate them to molecular structure. A common approach to go beyond the time- and length-scales accessible with such…

Accurate and efficient fluid flow models are essential for applications relating to many physical phenomena including geophysical, aerodynamic, and biological systems. While these flows may exhibit rich and multiscale dynamics, in many…

Fluid Dynamics · Physics 2024-08-27 Benjamin D. Shaffer , Jeremy R. Vorenberg , M. Ani Hsieh

Understanding large amounts of spatiotemporal data from particle-based simulations, such as molecular dynamics, often relies on the computation and analysis of aggregate measures. These, however, by virtue of aggregation, hide structural…

Computational Physics · Physics 2019-10-10 Juraj Pálenik , Jan Byška , Stefan Bruckner , Helwig Hauser

Deep learning-based generative models have emerged as powerful tools for modeling complex data distributions and generating high-fidelity samples, offering a transformative approach to efficiently explore the configuration space of…

Materials Science · Physics 2025-11-12 Xiaoshan Luo , Zhenyu Wang , Qingchang Wang , Jian Lv , Lei Wang , Yanchao Wang , Yanming Ma

Human blood flow is a multi-scale problem: in first approximation, blood is a dense suspension of plasma and deformable red cells. Physiological vessel diameters range from about one to thousands of cell radii. Current computational models…

Soft Condensed Matter · Physics 2015-03-17 Florian Janoschek , Federico Toschi , Jens Harting

In recent years, research and development in nanoscale science and technology have grown significantly, with electrical transport playing a key role. A natural challenge for its description is to shed light on anomalous behaviours observed…

Populations and Evolution · Quantitative Biology 2025-04-10 Sara Bernardi , Paolo Begnamino , Marco Pizzi , Lamberto Rondoni