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Quantile treatment effects (QTEs) can characterize the potentially heterogeneous causal effect of a treatment on different points of the entire outcome distribution. Propensity score (PS) methods are commonly employed for estimating QTEs in…

Methodology · Statistics 2023-08-15 Yahang Liu , Kecheng Wei , Chen Huang , Yongfu Yu , Guoyou Qin

We revisit the classical causal inference problem of estimating the average treatment effect in the presence of fully observed confounding variables using two-stage semiparametric methods. In existing theoretical studies of methods such as…

Methodology · Statistics 2022-05-23 Steve Yadlowsky

Meta-learning is a general approach to equip machine learning models with the ability to handle few-shot scenarios when dealing with many tasks. Most existing meta-learning methods work based on the assumption that all tasks are of equal…

Machine Learning · Computer Science 2024-10-25 Zhaofeng Si , Shu Hu , Kaiyi Ji , Siwei Lyu

Large language models (LLMs) have achieved remarkable performance on various natural language tasks. However, they are trained on static corpora and their knowledge can become outdated quickly in the fast-changing world. This motivates the…

Computation and Language · Computer Science 2025-05-29 Tianci Liu , Ruirui Li , Zihan Dong , Hui Liu , Xianfeng Tang , Qingyu Yin , Linjun Zhang , Haoyu Wang , Jing Gao

Background: Phase I dose-finding trials increasingly encounter delayed-onset toxicities, especially with immunotherapies and targeted agents. The time-to-event continual reassessment method (TITE-CRM) handles incomplete follow-up using…

Methodology · Statistics 2026-02-24 Robert Amevor , Emmanuel Kubuafor , Dennis Baidoo

Large Language Models (LLMs) often suffer from ''Reasoning Collapse'' on challenging mathematical reasoning tasks, where stochastic sampling produces lexical variations of the same erroneous logic rather than genuine semantic exploration.…

Artificial Intelligence · Computer Science 2026-04-30 Dayu Wang , Jiaye Yang , Weikang Li , Jiahui Liang , Yang Li , Deguo Xia , Jizhou Huang

Randomized trials are typically designed to detect average treatment effects but often lack the statistical power to uncover individual-level treatment effect heterogeneity, limiting their value for personalized decision-making. To address…

Machine Learning · Statistics 2026-03-19 Rickard Karlsson , Piersilvio De Bartolomeis , Issa J. Dahabreh , Jesse H. Krijthe

Estimating causal effects for survival outcomes in the high-dimensional setting is an extremely important topic for many biomedical applications as well as areas of social sciences. We propose a new orthogonal score method for treatment…

Methodology · Statistics 2024-12-04 Jue Hou , Jelena Bradic , Ronghui Xu

Meta-learning leverages related source tasks to learn an initialization that can be quickly fine-tuned to a target task with limited labeled examples. However, many popular meta-learning algorithms, such as model-agnostic meta-learning…

Machine Learning · Statistics 2020-03-24 Diana Cai , Rishit Sheth , Lester Mackey , Nicolo Fusi

Uplift modeling and Heterogeneous Treatment Effect (HTE) estimation aim at predicting the causal effect of an action, such as a medical treatment or a marketing campaign on a specific individual. In this paper, we focus on data from…

Machine Learning · Computer Science 2024-12-16 Krzysztof Rudaś , Szymon Jaroszewicz

This paper studies the problem of estimating individualized treatment rules when treatment effects are partially identified, as it is often the case with observational data. By drawing connections between the treatment assignment problem…

Econometrics · Economics 2023-01-02 Riccardo D'Adamo

Meta-learning aims to leverage information across related tasks to improve prediction on unlabeled data for new tasks when only a small number of labeled observations are available ("few-shot" learning). Increased task diversity is often…

Machine Learning · Statistics 2026-01-16 Saptati Datta , Nicolas W. Hengartner , Yulia Pimonova , Natalie E. Klein , Nicholas Lubbers

Personalized medicine has received increasing attention among statisticians, computer scientists, and clinical practitioners. A major component of personalized medicine is the estimation of individualized treatment rules (ITRs). Recently,…

Methodology · Statistics 2015-08-14 Xin Zhou , Nicole Mayer-Hamblett , Umer Khan , Michael R. Kosorok

Imbalanced data pose challenges for deep learning based classification models. One of the most widely-used approaches for tackling imbalanced data is re-weighting, where training samples are associated with different weights in the loss…

Machine Learning · Computer Science 2022-08-08 Dandan Guo , Zhuo Li , Meixi Zheng , He Zhao , Mingyuan Zhou , Hongyuan Zha

Estimation of individualized treatment effects (ITE) from observational studies is a fundamental problem in causal inference and holds significant importance across domains, including healthcare. However, limited observational datasets pose…

Machine Learning · Computer Science 2024-02-14 Vinod Kumar Chauhan , Jiandong Zhou , Ghadeer Ghosheh , Soheila Molaei , David A. Clifton

Variational autoencoder (VAE) neural networks can be trained to generate power system states that capture both marginal distribution and multivariate dependencies of historical data. The coordinates of the latent space codes of VAEs have…

Systems and Control · Electrical Eng. & Systems 2023-03-22 Chenguang Wang , Ensieh Sharifnia , Simon H. Tindemans , Peter Palensky

We propose a novel method, termed the M-learner, for estimating heterogeneous indirect and total treatment effects and identifying relevant subgroups within a mediation framework. The procedure comprises four key steps. First, we compute…

Machine Learning · Statistics 2025-08-14 Xingyu Li , Qing Liu , Tony Jiang , Hong Amy Xia , Brian P. Hobbs , Peng Wei

Due to potential applications in chronic disease management and personalized healthcare, the EHRs data analysis has attracted much attention of both researchers and practitioners. There are three main challenges in modeling longitudinal and…

Machine Learning · Computer Science 2019-12-03 Yi Huang , Xiaoshan Yang , Changsheng Xu

Heterogeneous treatment effects (HTE) based on patients' genetic or clinical factors are of significant interest to precision medicine. Simultaneously modeling HTE and corresponding main effects for randomized clinical trials with…

Machine Learning · Statistics 2023-02-06 Heng Chen , Michael L. LeBlanc , James Y. Dai

Meta learning of optimal classifier error rates allows an experimenter to empirically estimate the intrinsic ability of any estimator to discriminate between two populations, circumventing the difficult problem of estimating the optimal…

Machine Learning · Statistics 2017-11-01 Morteza Noshad Iranzad , Alfred O. Hero
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