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In this paper, we describe a dataset relating to cellular and physical conditions of patients who are operated upon to remove colorectal tumours. This data provides a unique insight into immunological status at the point of tumour removal,…

Machine Learning · Computer Science 2013-07-08 Chris Roadknight , Uwe Aickelin , Alex Ladas , Daniele Soria , John Scholefield , Lindy Durrant

Multiplexed immuno-fluorescence tissue imaging, allowing simultaneous detection of molecular properties of cells, is an essential tool for characterizing the complex cellular mechanisms in translational research and clinical practice. New…

Cluster analysis methods are used to identify homogeneous subgroups in a data set. In biomedical applications, one frequently applies cluster analysis in order to identify biologically interesting subgroups. In particular, one may wish to…

Methodology · Statistics 2016-09-23 Sheila Gaynor , Eric Bair

We present a non-invasive, label-free method of imaging blood cells flowing through human capillaries in vivo using oblique back-illumination capillaroscopy (OBC). Green light illumination allows simultaneous phase and absorption contrast,…

Biological Physics · Physics 2020-01-20 Gregory N. McKay , Nela Mohan , Nicholas J. Durr

Single-cell multi-view clustering enables the exploration of cellular heterogeneity within the same cell from different views. Despite the development of several multi-view clustering methods, two primary challenges persist. Firstly, most…

Genomics · Quantitative Biology 2023-11-30 Dayu Hu , Zhibin Dong , Ke Liang , Jun Wang , Siwei Wang , Xinwang Liu

We propose a Classification Via Clustering (CVC) algorithm which enables existing clustering methods to be efficiently employed in classification problems. In CVC, training and test data are co-clustered and class-cluster distributions are…

Computer Vision and Pattern Recognition · Computer Science 2014-09-29 Arif Mahmood , Ajmal S. Mian

This paper presents a comprehensive methodology and comparative performance analysis for the automated classification and object detection of peripheral blood cells (PBCs) in microscopic images. Addressing the critical challenge of data…

Computer Vision and Pattern Recognition · Computer Science 2025-11-12 Siddharth Sahay

Pixel-accurate tracking of objects is a key element in many computer vision applications, often solved by iterated individual object tracking or instance segmentation followed by object matching. Here we introduce cross-classification…

Computer Vision and Pattern Recognition · Computer Science 2019-06-18 Yaron Meirovitch , Lu Mi , Hayk Saribekyan , Alexander Matveev , David Rolnick , Nir Shavit

It has been shown that for automated PAP-smear image classification, nucleus features can be very informative. Therefore, the primary step for automated screening can be cell-nuclei detection followed by segmentation of nuclei in the…

Computer Vision and Pattern Recognition · Computer Science 2018-06-26 Srishti Gautam , Harinarayan K. K. , Nirmal Jith , Anil K. Sao , Arnav Bhavsar , Adarsh Natarajan

Manual peripheral blood smear (PBS) analysis is labor intensive and subjective. While deep learning offers a promising alternative, a systematic evaluation of state of the art models such as YOLOv11 for fine grained PBS detection is still…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Mohamad Abou Ali , Mariam Abdulfattah , Baraah Al Hussein , Fadi Dornaika , Ali Cherry , Mohamad Hajj-Hassan , Lara Hamawy

Efficient detection and classification of blood cells are vital for accurate diagnosis and effective treatment of blood disorders. This study utilizes a YOLOv10 model trained on Roboflow data with images resized to 640x640 pixels across…

Image and Video Processing · Electrical Eng. & Systems 2025-08-19 Shilpa Choudhary , Sandeep Kumar , Pammi Sri Siddhaarth , Guntu Charitasri

A precise assessment of the risk of breast lesions can greatly lower it and assist physicians in choosing the best course of action. To categorise breast lesions, the majority of current computer-aided systems only use characteristics from…

Image and Video Processing · Electrical Eng. & Systems 2025-08-25 Muhaisin Tiyumba Nantogmah , Abdul-Barik Alhassan , Salamudeen Alhassan

Flow analysis carried out using phase contrast cardiac magnetic resonance imaging (PC-CMR) enables the quantification of important parameters that are used in the assessment of cardiovascular function. An essential part of this analysis is…

The rapid emergence of single-cell data has facilitated the study of many different biological conditions at the cellular level. Cluster analysis has been widely applied to identify cell types, capturing the essential patterns of the…

Genomics · Quantitative Biology 2025-02-03 Sebastian Pena , Lin Lin , Jia Li

Flow cytometry is often used to characterize the malignant cells in leukemia and lymphoma patients, traced to the level of the individual cell. Typically, flow cytometric data analysis is performed through a series of 2-dimensional…

Machine Learning · Statistics 2009-11-13 Kevin M. Carter , Raviv Raich , William G. Finn , Alfred O. Hero

We propose a deep clustering architecture alongside image segmentation for medical image analysis. The main idea is based on unsupervised learning to cluster images on severity of the disease in the subject's sample, and this image is then…

Image and Video Processing · Electrical Eng. & Systems 2020-05-28 Sharmin Pathan , Anant Tripathi

Automatization of the diagnosis of any kind of disease is of great importance and it's gaining speed as more and more deep learning solutions are applied to different problems. One of such computer aided systems could be a decision support…

Computer Vision and Pattern Recognition · Computer Science 2018-04-24 Tomas Iesmantas , Robertas Alzbutas

We propose a clustering-based approach for identifying coherent flow structures in continuous dynamical systems. We first treat a particle trajectory over a finite time interval as a high-dimensional data point and then cluster these data…

Dynamical Systems · Mathematics 2022-12-27 Wai Ming Chau , Shingyu Leung

The differentiation between pathological subtypes of non-small cell lung cancer (NSCLC) is an essential step in guiding treatment options and prognosis. However, current clinical practice relies on multi-step staining and labelling…

Quantitative Methods · Quantitative Biology 2026-03-10 Zhenya Zang , David A Dorward , Katherine E Quiohilag , Andrew DJ Wood , James R Hopgood , Ahsan R Akram , Qiang Wang

Wireless Capsule Endoscopy (WCE) is device to detect abnormalities in colon,esophagus,small intestinal and stomach, to distinguish bleeding in WCE images from non bleeding is a hard job by human reviewing and very time consuming.…

Computer Vision and Pattern Recognition · Computer Science 2010-07-15 Amer A. Al-Rahayfeh , Abdelshakour A. Abuzneid