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The usage of chemical imaging technologies is becoming a routine accompaniment to traditional methods in pathology. Significant technological advances have developed these next generation techniques to provide rich, spatially resolved,…

Machine Learning · Computer Science 2022-09-07 Spencer A. Thomas

Automating white blood cell classification for diagnosis of leukaemia is a promising alternative to time-consuming and resource-intensive examination of cells by expert pathologists. However, designing robust algorithms for classification…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Siddharth Srivastava , Adam Smith , Scott Brooks , Jack Bacon , Till Bretschneider

Morphologies of red blood cells are normally interpreted by a pathologist. It is time-consuming and laborious. Furthermore, a misclassified red blood cell morphology will lead to false disease diagnosis and improper treatment. Thus, a…

Image and Video Processing · Electrical Eng. & Systems 2025-02-06 Kitsuchart Pasupa , Supawit Vatathanavaro , Suchat Tungjitnob

We present a method for automatic cell classification in tissue samples using an automated training set from multiplexed immunofluorescence images. The method utilizes multiple markers stained in situ on a single tissue section on a robust…

Image and Video Processing · Electrical Eng. & Systems 2020-07-21 Alberto Santamaria-Pang , Anup Sood , Dan Meyer , Aritra Chowdhury , Fiona Ginty

Imaging flow cytometry systems aim to analyze a huge number of cells or micro-particles based on their physical characteristics. The vast majority of current systems acquire a large amount of images which are used to train deep artificial…

Neural and Evolutionary Computing · Computer Science 2023-03-21 Muhammed Gouda , Steven Abreu , Alessio Lugnan , Peter Bienstman

The application of machine learning techniques to the medical domain is especially challenging due to the required level of precision and the incurrence of huge risks of minute errors. Employing these techniques to a more complex subdomain…

Computer Vision and Pattern Recognition · Computer Science 2021-10-19 Ekta Gavas , Kaustubh Olpadkar

Cytology is the branch of pathology which deals with the microscopic examination of cells for diagnosis of carcinoma or inflammatory conditions. Automation in cytology started in the early 1950s with the aim to reduce manual efforts in…

Image and Video Processing · Electrical Eng. & Systems 2020-03-18 Shyamali Mitra , Nibaran Das , Soumyajyoti Dey , Sukanta Chakrabarty , Mita Nasipuri , Mrinal Kanti Naskar

Leukemia is diagnosed with complete blood counts which is by calculating all blood cells and compare the number of white blood cells (White Blood Cells / WBC) and red blood cells (Red Blood Cells / RBC). Information obtained from a complete…

Computer Vision and Pattern Recognition · Computer Science 2015-11-17 Esti Suryani , Wiharto Wiharto , Nizomjon Polvonov

Blood cell detection is a typical small-scale object detection problem in computer vision. In this paper, we propose a CST-YOLO model for blood cell detection based on YOLOv7 architecture and enhance it with the CNN-Swin Transformer (CST),…

Computer Vision and Pattern Recognition · Computer Science 2024-10-08 Ming Kang , Chee-Ming Ting , Fung Fung Ting , Raphaël Phan

Modern high-throughput sequencing technologies have enabled us to profile multiple molecular modalities from the same single cell, providing unprecedented opportunities to assay celluar heterogeneity from multiple biological layers.…

Machine Learning · Statistics 2022-05-20 Pengcheng Zeng , Zhixiang Lin

Analysis of flow cytometry data is an essential tool for clinical diagnosis of hematological and immunological conditions. Current clinical workflows rely on a manual process called gating to classify cells into their canonical types. This…

Machine Learning · Statistics 2017-11-29 Disi Ji , Eric Nalisnick , Padhraic Smyth

Diagnosing basal cell carcinomas (BCC), one of the most common cutaneous malignancies in humans, is a task regularly performed by pathologists and dermato-pathologists. Improving histological diagnosis by providing diagnosis suggestions,…

Chromosome analysis and identification from metaphase images is a critical part of cytogenetics based medical diagnosis. It is mainly used for identifying constitutional, prenatal and acquired abnormalities in the diagnosis of genetic…

Computer Vision and Pattern Recognition · Computer Science 2022-09-13 Amritha S Pallavoor , Prajwal A , Sundareshan TS , Sreekanth K Pallavoor

Accurately and quickly binuclear cell (BC) detection plays a significant role in predicting the risk of leukemia and other malignant tumors. However, manual microscopy counting is time-consuming and lacks objectivity. Moreover, with the…

Computer Vision and Pattern Recognition · Computer Science 2022-08-29 Baomin Wang , Geng Hu , Dan Chen , Lihua Hu , Cheng Li , Yu An , Guiping Hu , Guang Jia

Convolutional neural networks (CNNs) deliver exceptional results for computer vision, including medical image analysis. With the growing number of available architectures, picking one over another is far from obvious. Existing art suggests…

Computer Vision and Pattern Recognition · Computer Science 2019-04-30 Fábio Perez , Sandra Avila , Eduardo Valle

White blood cells (WBCs) are the most diverse cell types observed in the healing process of injured skeletal muscles. In the course of healing, WBCs exhibit dynamic cellular response and undergo multiple protein expression changes. The…

Image and Video Processing · Electrical Eng. & Systems 2024-09-12 Yang Jiao , Hananeh Derakhshan , Barbara St. Pierre Schneider , Emma Regentova , Mei Yang

Accurate classification of blood cells plays a vital role in hematological analysis as it aids physicians in diagnosing various medical conditions. In this study, we present a novel approach for classifying blood cell images known as…

Computer Vision and Pattern Recognition · Computer Science 2024-08-14 Yongcheng Li , Lingcong Cai , Ying Lu , Yupeng Zhang , Jingyan Jiang , Genan Dai , Bowen Zhang , Jingzhou Cao , Xiangzhong Zhang , Xiaomao Fan

Explainability for Deep Learning Models is especially important for clinical applications, where decisions of automated systems have far-reaching consequences. While various post-hoc explainable methods, such as attention visualization and…

The detection of blood disorders often hinges upon the quantification of specific blood cell types. Variations in cell counts may indicate the presence of pathological conditions. Thus, the significance of developing precise automatic…

Image and Video Processing · Electrical Eng. & Systems 2025-03-24 Davide Antonio Mura , Michela Pinna , Lorenzo Putzu , Andrea Loddo , Alessandra Perniciano , Olga Mulas , Cecilia Di Ruberto
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