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Counting cells in fluorescent microscopy is a tedious, time-consuming task that researchers have to accomplish to assess the effects of different experimental conditions on biological structures of interest. Although such objects are…

Computer Vision and Pattern Recognition · Computer Science 2021-03-02 R. Morelli , L. Clissa , M. Dalla , M. Luppi , L. Rinaldi , A. Zoccoli

Recent advances in deep learning have enabled the development of automated frameworks for analysing medical images and signals, including analysis of cervical cancer. Many previous works focus on the analysis of isolated cervical cells, or…

Computer Vision and Pattern Recognition · Computer Science 2024-03-06 Ruiqi Wang , Mohammad Ali Armin , Simon Denman , Lars Petersson , David Ahmedt-Aristizabal

Chromatic Correlation Clustering (CCC) generalizes Correlation Clustering by assigning multiple categorical relationships (colors) to edges and imposing chromatic constraints on the clusters. Unlike traditional Correlation Clustering, which…

Data Structures and Algorithms · Computer Science 2025-07-22 Dahoon Lee , Chenglin Fan , Euiwoong Lee

Melanoma is a fatal skin cancer that is curable and has dramatically increasing survival rate when diagnosed at early stages. Learning-based methods hold significant promise for the detection of melanoma from dermoscopic images. However,…

Image and Video Processing · Electrical Eng. & Systems 2022-04-06 Saban Ozturk , Tolga Cukur

Confocal laser endomicroscopy (CLE) is an advanced optical fluorescence technology undergoing assessment for applications in brain tumor surgery. Despite its promising potential, interpreting the unfamiliar gray tone images of fluorescent…

Computer Vision and Pattern Recognition · Computer Science 2018-08-21 Mohammadhassan Izadyyazdanabadi , Evgenii Belykh , Michael Mooney , Nikolay Martirosyan , Jennifer Eschbacher , Peter Nakaji , Mark C. Preul , Yezhou Yang

Breast cancer is a significant global health issue, and the diagnosis of breast cancer through imaging remains challenging. Mammography images are characterized by extremely high resolution, while lesions often occupy only a small portion…

Tissues and Organs · Quantitative Biology 2025-07-28 Shilong Yang , Chulong Zhang , Xiaokun Liang , Qi Zang , Juan Yu , Liang Zeng , Xiao Luo , Yexuan Xing , Xin Pan , Qi Li , Linlin Shen , Yaoqin Xie

Clustering algorithms are one of the main analytical methods to detect patterns in unlabeled data. Existing clustering methods typically treat samples in a dataset as points in a metric space and compute distances to group together similar…

Machine Learning · Computer Science 2021-10-12 Tarek Naous , Srinjay Sarkar , Abubakar Abid , James Zou

Label-free cell classification is advantageous for supplying pristine cells for further use or examination, yet existing techniques frequently fall short in terms of specificity and speed. In this study, we address these limitations through…

Image and Video Processing · Electrical Eng. & Systems 2025-02-25 Khayrul Islam , Ratul Paul , Shen Wang , Yuwen Zhao , Partho Adhikary , Qiying Li , Xiaochen Qin , Yaling Liu

Cells, other than their biological properties, have different electric and physical properties. In an impedance cytometer, cells should pass one by one in the detection region where pairs of electrodes are located. When cells are located…

Signal Processing · Electrical Eng. & Systems 2022-03-09 Hassan Raji , Iraj Dehghan Hamani

The classification of white blood cells (WBCs) from peripheral blood smears is critical for the diagnosis of leukemia. However, automated approaches still struggle due to challenges including class imbalance, domain shift, and morphological…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Antony Gitau , Martin Paulson , Bjørn-Jostein Singstad , Karl Thomas Hjelmervik , Ola Marius Lysaker , Veralia Gabriela Sanchez

Ocean microbes are critical to both ocean ecosystems and the global climate. Flow cytometry, which measures cell optical properties in fluid samples, is routinely used in oceanographic research. Despite decades of accumulated data,…

Methodology · Statistics 2025-04-17 Sangwon Hyun , Tim Coleman , Francois Ribalet , Jacob Bien

Diffuse correlation spectroscopy (DCS) analyzes the autocorrelation function of photons scattered by red blood cells, enabling non-invasive, continuous measurement of deep tissue blood flow at the bedside. Multi-layer DCS models (two- and…

We present a new method for photometering objects in galaxy clusters. We introduce a mode-filtering technique for removing spatially variable backgrounds, improving both detection and photometric accuracy (roughly halving the scatter in the…

With the rapid development of digital pathology, virtual staining has become a key technology in multimedia medical information systems, offering new possibilities for the analysis and diagnosis of pathological images. However, existing…

Computer Vision and Pattern Recognition · Computer Science 2025-06-10 Hao Yang , JianYu Wu , Run Fang , Xuelian Zhao , Yuan Ji , Zhiyu Chen , Guibin He , Junceng Guo , Yang Liu , Xinhua Zeng

Deep learning-based medical image classification techniques are rapidly advancing in medical image analysis, making it crucial to develop accurate and trustworthy models that can be efficiently deployed across diverse clinical scenarios.…

Computer Vision and Pattern Recognition · Computer Science 2025-06-24 Hangzhou He , Jiachen Tang , Lei Zhu , Kaiwen Li , Yanye Lu

The evolutionary classification of molecular clumps, crucial for understanding star formation, is commonly based on human-assigned categories derived from infrared (IR) emission and well-established morphological criteria. However, due to…

Astrophysics of Galaxies · Physics 2026-02-27 K. V. Plakitina , M. S. Kirsanova , A. B. Ostrovskii , A. D. Gimalieva , S. V. Salii , A. V. Meshcheryakov

Diffuse correlation spectroscopy (DCS) is an emerging noninvasive technique that measures the tissue blood flow, by using near-infrared coherent point-source illumination to detect spectral changes. While machine learning has demonstrated…

Machine Learning · Computer Science 2024-02-02 Xi Chen , Xingda Li

Biomedical imaging and RNA sequencing with single-cell resolution improves our understanding of white blood cell diseases like leukemia. By combining morphological and transcriptomic data, we can gain insights into cellular functions and…

Computer Vision and Pattern Recognition · Computer Science 2024-08-26 Gizem Mert , Ario Sadafi , Raheleh Salehi , Nassir Navab , Carsten Marr

Colorectal cancer (CRC) grading is typically carried out by assessing the degree of gland formation within histology images. To do this, it is important to consider the overall tissue micro-environment by assessing the cell-level…

Image and Video Processing · Electrical Eng. & Systems 2019-09-04 Yanning Zhou , Simon Graham , Navid Alemi Koohbanani , Muhammad Shaban , Pheng-Ann Heng , Nasir Rajpoot

Automatic detection and classification of Cardiovascular disease (CVD) from Computed Tomography (CT) images play an important part in facilitating better-informed clinical decisions. However, most of the recent deep learning based methods…

Image and Video Processing · Electrical Eng. & Systems 2026-05-07 Ajay Mittal , Raghav Mehta , Omar Todd , Philipp Seeböck , Georg Langs , Ben Glocker