English
Related papers

Related papers: Evaluating protein binding interfaces with PUMBA

200 papers

Due to the lack of a method to efficiently represent the multimodal information of a protein, including its structure and sequence information, predicting compound-protein binding affinity (CPA) still suffers from low accuracy when applying…

Biomolecules · Quantitative Biology 2022-11-28 Binjie Guo , Hanyu Zheng , Haohan Jiang , Xiaodan Li , Naiyu Guan , Yanming Zuo , Yicheng Zhang , Hengfu Yang , Xuhua Wang

Designing computationally efficient network architectures remains an ongoing necessity in computer vision. In this paper, we adapt Mamba, a state-space language model, into VMamba, a vision backbone with linear time complexity. At the core…

Computer Vision and Pattern Recognition · Computer Science 2024-12-31 Yue Liu , Yunjie Tian , Yuzhong Zhao , Hongtian Yu , Lingxi Xie , Yaowei Wang , Qixiang Ye , Jianbin Jiao , Yunfan Liu

Crack detection is a critical task in structural health monitoring, aimed at assessing the structural integrity of bridges, buildings, and roads to prevent potential failures. Vision-based crack detection has become the mainstream approach…

Computer Vision and Pattern Recognition · Computer Science 2026-01-26 Qinfeng Zhu , Yuan Fang , Lei Fan

Recent Mamba-based image restoration methods have achieved promising results but remain limited by fixed scanning patterns and inefficient feature utilization. Conventional Mamba architectures rely on predetermined paths that cannot adapt…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Han Hu , Zhuoran Zheng , Liang Li , Chen Lyu

In the design of surgical guides for implant placement, determining the precise implant position is a critical step. However, the implant region itself is often characterized by a lack of distinctive texture in medical images. Consequently,…

Computer Vision and Pattern Recognition · Computer Science 2026-05-11 Xinquan Yang , Congmin Wang , Xuguang Li , Yulei Li , Linlin Shen , Yongqiang Deng He Meng

White blood cell (WBC) classification assists in assessing immune health and diagnosing various diseases, yet manual classification is labor-intensive and prone to inconsistencies. Recent advancements in deep learning have shown promise…

The goal of protein representation learning is to extract knowledge from protein databases that can be applied to various protein-related downstream tasks. Although protein sequence, structure, and function are the three key modalities for…

Biomolecules · Quantitative Biology 2024-05-14 Eunji Ko , Seul Lee , Minseon Kim , Dongki Kim

A fundamental objective in robot manipulation is to enable models to comprehend visual scenes and execute actions. Although existing Vision-Language-Action (VLA) models for robots can handle a range of basic tasks, they still face…

Computer Vision and Pattern Recognition · Computer Science 2024-12-17 Jiaming Liu , Mengzhen Liu , Zhenyu Wang , Pengju An , Xiaoqi Li , Kaichen Zhou , Senqiao Yang , Renrui Zhang , Yandong Guo , Shanghang Zhang

3D object detection is critical for autonomous driving, yet it remains fundamentally challenging to simultaneously maximize computational efficiency and capture long-range spatial dependencies. We observed that Mamba-based models, with…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Longhui Zheng , Qiming Xia , Xiaolu Chen , Zhaoliang Liu , Chenglu Wen

Transformer structure has achieved great success in multiple applied machine learning communities, such as natural language processing (NLP), computer vision (CV) and information retrieval (IR). Transformer architecture's core mechanism\,…

Information Retrieval · Computer Science 2026-01-06 Zhichao Xu

Recent advances in self-supervised learning for Vision Transformers (ViTs) have fueled breakthroughs in remote sensing (RS) foundation models. However, the quadratic complexity of self-attention poses a significant barrier to scalability,…

Computer Vision and Pattern Recognition · Computer Science 2025-11-05 Fengxiang Wang , Yulin Wang , Mingshuo Chen , Haiyan Zhao , Yangang Sun , Shuo Wang , Hongzhen Wang , Di Wang , Long Lan , Wenjing Yang , Jing Zhang

The diffusion model has long been plagued by scalability and quadratic complexity issues, especially within transformer-based structures. In this study, we aim to leverage the long sequence modeling capability of a State-Space Model called…

Computer Vision and Pattern Recognition · Computer Science 2024-11-26 Vincent Tao Hu , Stefan Andreas Baumann , Ming Gui , Olga Grebenkova , Pingchuan Ma , Johannes Schusterbauer , Björn Ommer

We propose TRAMBA, a hybrid transformer and Mamba architecture for acoustic and bone conduction speech enhancement, suitable for mobile and wearable platforms. Bone conduction speech enhancement has been impractical to adopt in mobile and…

Sound · Computer Science 2024-05-30 Yueyuan Sui , Minghui Zhao , Junxi Xia , Xiaofan Jiang , Stephen Xia

We introduce VideoMamba, a novel adaptation of the pure Mamba architecture, specifically designed for video recognition. Unlike transformers that rely on self-attention mechanisms leading to high computational costs by quadratic complexity,…

Computer Vision and Pattern Recognition · Computer Science 2024-07-12 Jinyoung Park , Hee-Seon Kim , Kangwook Ko , Minbeom Kim , Changick Kim

Predicting accurate protein-ligand binding affinity is important in drug discovery but remains a challenge even with computationally expensive biophysics-based energy scoring methods and state-of-the-art deep learning approaches. Despite…

Existing state-of-the-art feature matchers capture long-range dependencies with Transformers but are hindered by high spatial complexity, leading to demanding training and highlatency inference. Striking a better balance between performance…

Computer Vision and Pattern Recognition · Computer Science 2025-03-06 Xiaoyong Lu , Songlin Du

In recent years, computer vision has witnessed remarkable progress, fueled by the development of innovative architectures such as Convolutional Neural Networks (CNNs), Generative Adversarial Networks (GANs), diffusion-based architectures,…

Computer Vision and Pattern Recognition · Computer Science 2026-05-27 Mamadou Keita , Wassim Hamidouche , Hessen Bougueffa Eutamene , Abdelmalik Taleb-Ahmed , Xianxun Zhu , Abdenour Hadid

Cross-modality fusing complementary information from different modalities effectively improves object detection performance, making it more useful and robust for a wider range of applications. Existing fusion strategies combine different…

Computer Vision and Pattern Recognition · Computer Science 2025-07-23 Wenhao Dong , Haodong Zhu , Shaohui Lin , Xiaoyan Luo , Yunhang Shen , Xuhui Liu , Juan Zhang , Guodong Guo , Baochang Zhang

Skin lesion segmentation is a crucial method for identifying early skin cancer. In recent years, both convolutional neural network (CNN) and Transformer-based methods have been widely applied. Moreover, combining CNN and Transformer…

Image and Video Processing · Electrical Eng. & Systems 2024-09-18 Shun Zou , Mingya Zhang , Bingjian Fan , Zhengyi Zhou , Xiuguo Zou

This study explores replacing Transformers in Visual Language Models (VLMs) with Mamba, a recent structured state space model (SSM) that demonstrates promising performance in sequence modeling. We test models up to 3B parameters under…

Computer Vision and Pattern Recognition · Computer Science 2024-10-02 Georgios Pantazopoulos , Malvina Nikandrou , Alessandro Suglia , Oliver Lemon , Arash Eshghi