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Related papers: BiomedXPro: Prompt Optimization for Explainable Di…

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Generalist Medical AI (GMAI) systems have demonstrated expert-level performance in biomedical perception tasks, yet their clinical utility remains limited by inadequate multi-modal explainability and suboptimal prognostic capabilities.…

Computer Vision and Pattern Recognition · Computer Science 2025-05-13 Honglong Yang , Shanshan Song , Yi Qin , Lehan Wang , Haonan Wang , Xinpeng Ding , Qixiang Zhang , Bodong Du , Xiaomeng Li

Deep learning-based medical image analysis faces a significant barrier due to the lack of interpretability. Conventional explainable AI (XAI) techniques, such as Grad-CAM and SHAP, often highlight regions outside clinical interests. To…

Image and Video Processing · Electrical Eng. & Systems 2025-02-17 Yuhao Zhang , Mingcheng Zhu , Zhiyao Luo

Prompt-driven image analysis converts a single natural-language instruction into multiple steps: locate, segment, edit, and describe. We present a practical case study of a unified pipeline that combines open-vocabulary detection,…

Computer Vision and Pattern Recognition · Computer Science 2025-09-11 Kaleem Ahmad

Vision-language foundation models have emerged as powerful general-purpose representation learners with strong potential for multimodal understanding, but their deterministic embeddings often fail to provide the reliability required for…

Computer Vision and Pattern Recognition · Computer Science 2026-02-19 Ahmad Elallaf , Yu Zhang , Yuktha Priya Masupalli , Jeong Yang , Young Lee , Zechun Cao , Gongbo Liang

Test-time prompt tuning for vision-language models has demonstrated impressive generalization capabilities under zero-shot settings. However, tuning the learnable prompts solely based on unlabeled test data may induce prompt optimization…

Machine Learning · Computer Science 2025-11-18 Fei Song , Yi Li , Rui Wang , Jiahuan Zhou , Changwen Zheng , Jiangmeng Li

The inability to interpret the model prediction in semantically and visually meaningful ways is a well-known shortcoming of most existing computer-aided diagnosis methods. In this paper, we propose MDNet to establish a direct multimodal…

Computer Vision and Pattern Recognition · Computer Science 2017-07-11 Zizhao Zhang , Yuanpu Xie , Fuyong Xing , Mason McGough , Lin Yang

Monocular 3D object detection typically relies on pseudo-labeling techniques to reduce dependency on real-world annotations. Recent advances demonstrate that deterministic linguistic cues can serve as effective auxiliary weak supervision…

Computer Vision and Pattern Recognition · Computer Science 2026-03-23 Chupeng Liu , Jiyong Rao , Shangquan Sun , Runkai Zhao , Weidong Cai

The Medical Segment Anything Model (MedSAM) has shown remarkable performance in medical image segmentation, drawing significant attention in the field. However, its sensitivity to varying prompt types and locations poses challenges. This…

Computer Vision and Pattern Recognition · Computer Science 2024-09-04 Nan Zhou , Ke Zou , Kai Ren , Mengting Luo , Linchao He , Meng Wang , Yidi Chen , Yi Zhang , Hu Chen , Huazhu Fu

Large pre-trained vision-language models (VLMs) offer a promising approach to leveraging human language for enhancing downstream tasks. However, VLMs such as CLIP face significant limitation: its performance is highly sensitive to prompt…

Computer Vision and Pattern Recognition · Computer Science 2025-03-13 Ao Li , Zongfang Liu , Xinhua Li , Jinghui Zhang , Pengwei Wang , Hu Wang

Current text-to-image (T2I) benchmarks evaluate models on rigid prompts, potentially underestimating true generative capabilities due to prompt sensitivity and creating biases that favor certain models while disadvantaging others. We…

Computer Vision and Pattern Recognition · Computer Science 2025-07-08 Haosheng Gan , Berk Tinaz , Mohammad Shahab Sepehri , Zalan Fabian , Mahdi Soltanolkotabi

Multimodal large language models (MLLMs) hold considerable promise for applications in healthcare. However, their deployment in safety-critical settings is hindered by two key limitations: (i) sensitivity to prompt design, and (ii) a…

Computer Vision and Pattern Recognition · Computer Science 2025-10-14 Anita Kriz , Elizabeth Laura Janes , Xing Shen , Tal Arbel

The clinical adoption of artificial intelligence (AI) in medical imaging requires models that are both diagnostically accurate and interpretable to clinicians. While current multimodal biomedical foundation models prioritize performance,…

Medical decision-making requires integrating diverse medical information, from imaging to clinical narratives. These medical modalities are often acquired in a many-to-many manner. However, current medical vision-language pretraining models…

Computer Vision and Pattern Recognition · Computer Science 2025-10-01 Yuan Gao , Sangwook Kim , Jianzhong You , Chris McIntosh

Recently, large models have shown significant potential for smart healthcare. However, the deployment of Large Vision-Language Models (LVLMs) for clinical services is currently hindered by three critical challenges: a tendency to…

Artificial Intelligence · Computer Science 2025-10-27 Siyong Chen , Jinbo Wen , Jiawen Kang , Tenghui Huang , Xumin Huang , Yuanjia Su , Hudan Pan , Zishao Zhong , Dusit Niyato , Shengli Xie , Dong In Kim

The clinical adoption of artificial intelligence (AI) in medical diagnostics is critically hampered by its black-box nature, which prevents clinicians from verifying the rationale behind automated decisions. To overcome this fundamental…

The alignment of large language models (LLMs) with human values is critical as these models become increasingly integrated into various societal and decision-making processes. Traditional methods, such as reinforcement learning from human…

Machine Learning · Computer Science 2025-01-08 Prashant Trivedi , Souradip Chakraborty , Avinash Reddy , Vaneet Aggarwal , Amrit Singh Bedi , George K. Atia

Despite the success of deep learning in dermoscopy image analysis, its inherent black-box nature hinders clinical trust, motivating the use of prototypical networks for case-based visual transparency. However, inevitable selection bias in…

Image and Video Processing · Electrical Eng. & Systems 2026-03-02 Junhao Jia , Yueyi Wu , Huangwei Chen , Haodong Jing , Haishuai Wang , Jiajun Bu , Lei Wu

Biomedical language understanding benchmarks are the driving forces for artificial intelligence applications with large language model (LLM) back-ends. However, most current benchmarks: (a) are limited to English which makes it challenging…

Computation and Language · Computer Science 2023-10-24 Wei Zhu , Xiaoling Wang , Huanran Zheng , Mosha Chen , Buzhou Tang

Healthcare professionals need effective ways to use, understand, and validate AI-driven clinical decision support systems. Existing systems face two key limitations: complex visualizations and a lack of grounding in scientific evidence. We…

Human-Computer Interaction · Computer Science 2025-07-08 Reza Samimi , Aditya Bhattacharya , Lucija Gosak , Gregor Stiglic , Katrien Verbert

Large Language Models (LLMs) have shown remarkable success, and their multimodal expansions (MLLMs) further unlock capabilities spanning images, videos, and other modalities beyond text. However, despite this shift, prompt optimization…

Machine Learning · Computer Science 2026-02-20 Yumin Choi , Dongki Kim , Jinheon Baek , Sung Ju Hwang