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Positron emission tomography (PET) scanners continue to increase sensitivity and axial coverage by adding an ever expanding array of block detectors. As they age, one or more block detectors may lose sensitivity due to a malfunction or…

Medical Physics · Physics 2019-10-17 William Whiteley , Jens Gregor

Positron Emission Mammography imaging system (PEMi) is a nuclear medicine diagnosis method dedicated for breast imaging. It provides a better resolution in detection of millimeter-sized breast tumors than whole-body PET. To address the…

Medical Physics · Physics 2015-10-28 Xiao-Yue Gu , Lin Li , Peng-Fei Yin , Ming-Kai Yun , Chai Pei , Xin Fan , Xian-Chao Huang , Xiao-Li Sun , Long Wei

Positron Emission Tomography (PET) enables functional imaging of deep brain structures, but the bulk and weight of current systems preclude their use during many natural human activities, such as locomotion. The proposed long-term solution…

Robotics · Computer Science 2023-12-07 Junxiang Wang , Ti Wu , Iulian I. Iordachita , Peter Kazanzides

Positron emission tomography (PET) imaging is widely used in a number of clinical applications, including cancer and Alzheimer's disease (AD) diagnosis, monitoring of disease development, and treatment effect evaluation. Statistical…

Tissues and Organs · Quantitative Biology 2025-11-07 Akhil Ambekar , Robert Zielinski , Ani Eloyan

The aim of this paper is to test and analyze a novel technique for image reconstruction in positron emission tomography, which is based on (total variation) regularization on both the image space and the projection space. We formulate our…

Numerical Analysis · Mathematics 2014-07-24 Martin Burger , Jahn Müller , Evangelos Papoutsellis , Carola-Bibiane Schönlieb

Total-body positron emission tomography (PET) imaging has the potential to transform medical care of a number of diseases and augment our knowledge of systems biology. Various detector designs and geometries are currently under development…

To correct for respiratory motion in PET imaging, an interpretable and unsupervised deep learning technique, FlowNet-PET, was constructed. The network was trained to predict the optical flow between two PET frames from different breathing…

Image and Video Processing · Electrical Eng. & Systems 2022-08-04 Teaghan O'Briain , Carlos Uribe , Kwang Moo Yi , Jonas Teuwen , Ioannis Sechopoulos , Magdalena Bazalova-Carter

Positron Emission Tomography (PET) scanners are usually designed with the goal to obtain the best compromise between sensitivity, resolution, field-of-view size, and cost. Therefore, it is difficult to improve the resolution of a PET…

Medical Physics · Physics 2023-07-18 Pablo Galve , Alejandro Lopez-Montes , Jose M Udias , Stephen C Moore , Joaquin L Herraiz

Positron Emission Tomography (PET) enables functional imaging of deep brain structures, but the bulk and weight of current systems preclude their use during many natural human activities, such as locomotion. The proposed long-term solution…

Robotics · Computer Science 2023-12-01 Junxiang Wang , Ti Wu , Iulian I. Iordachita , Peter Kazanzides

Intraoperative Gamma Probe (IPG) remains the current gold standard modality for sentinel lymph node identification and tumor removal in cancer patients. However, even alongside the optical dyes they do not meet with <5% false negative rates…

Medical Physics · Physics 2022-01-26 S. Sajedi , L. Blackberg , S. Majewski , H. Sabet

Poisson distributed measurements in inverse problems often stem from Poisson point processes that are observed through discretized or finite-resolution detectors, one of the most prominent examples being positron emission tomography (PET).…

Statistics Theory · Mathematics 2024-07-25 Marco Mauritz , Benedikt Wirth

We are currently conceiving, through (MC) simulation, a multi-channel gamma detector array (TIARA for Time-of-flight Imaging ARrAy) for the online monitoring of protontherapy treatments. By measuring the Time-Of-Flight (TOF) between a beam…

In spring 2019 the international atomic energy agency (IAEA) has run a public competition to look at tomographic reconstruction algorithms for its PGET detector, used to determine activity levels in nuclear reactors spent fuel rods. The…

Medical Physics · Physics 2019-10-16 Luca Presotto

The ability to synthesise Computed Tomography images - commonly known as pseudo CT, or pCT - from MRI input data is commonly assessed using an intensity-wise similarity, such as an L2-norm between the ground truth CT and the pCT. However,…

Image and Video Processing · Electrical Eng. & Systems 2020-04-15 Kerstin Kläser , Thomas Varsavsky , Pawel Markiewicz , Tom Vercauteren , David Atkinson , Kris Thielemans , Brian Hutton , M Jorge Cardoso , Sebastien Ourselin

Motion, e.g., due to patient movement or improper device calibration, is inevitable in many imaging modalities such as photoacoustic tomography (PAT) by a rotating system and can lead to undesirable motion artifacts in image…

Numerical Analysis · Mathematics 2016-09-28 Julianne Chung , Linh Nguyen

Positron Emission Tomography (PET) is a functional imaging modality that enables the visualization of biochemical and physiological processes across various tissues. Recently, deep learning (DL)-based methods have demonstrated significant…

Image and Video Processing · Electrical Eng. & Systems 2026-01-16 Yiran Sun , Osama Mawlawi

We propose a novel dynamic image reconstruction method from PET listmode data that could be particularly suited to tracking single or small numbers of cells. In contrast to conventional PET reconstruction our method combines the information…

Computer Vision and Pattern Recognition · Computer Science 2019-11-25 Bernhard Schmitzer , Klaus P. Schäfers , Benedikt Wirth

Photon attenuation and scatter are the two main physical factors affecting the diagnostic quality of SPECT in its applications in brain imaging. In this work, we present a novel Bayesian Optimization approach for Attenuation Correction…

Medical Physics · Physics 2021-09-27 Loizos Koutsantonis , Ayman Makki , Tiago Carneiro , Emmanuel Kieffer , Pascal Bouvry

Reducing scan time in Positron Emission Tomography (PET) imaging while maintaining high-quality images is crucial for minimizing patient discomfort and radiation exposure. Due to the limited size of datasets and distribution discrepancy…

Image and Video Processing · Electrical Eng. & Systems 2024-07-11 Yumin Kim , Gayoon Choi , Seong Jae Hwang

The integration of Time-of-Flight (TOF) information in the reconstruction process of Positron Emission Tomography (PET) yields improved image properties. However, implementing the cutting-edge model-based deep learning methods for TOF-PET…

Image and Video Processing · Electrical Eng. & Systems 2023-02-22 Chenxu Li , Rui Hu , Jianan Cui , Huafeng Liu