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We present simulations of whole-body low-dose time-of-flight positron emission tomography (TOF-PET) based on the direct surface production [1] by 511 keV gamma rays of energetic electrons via the Photo-electric and Compton Effects,…

Positron Emission Tomography (PET) is a Nuclear Medicine technique that creates images that allow the study of metabolic activity and organ function using radiopharmaceuticals. Continuous improvement of scintillation detectors for radiation…

In PET/CT imaging, CT is used for PET attenuation correction (AC). Mismatch between CT and PET due to patient body motion results in AC artifacts. In addition, artifact caused by metal, beam-hardening and count-starving in CT itself also…

Image and Video Processing · Electrical Eng. & Systems 2019-09-05 Luyao Shi , John A. Onofrey , Enette Mae Revilla , Takuya Toyonaga , David Menard , Jo-seph Ankrah , Richard E. Carson , Chi Liu , Yihuan Lu

Quantifying material mass and electron density from computed tomography (CT) reconstructions can be highly valuable in certain medical practices, such as radiation therapy planning. However, uniquely parameterising the X-ray attenuation in…

Medical Physics · Physics 2019-04-30 Jonathan H. Mason , Alessandro Perelli , William H. Nailon , Mike E. Davies

The single-scatter approximation is fundamental in many tomographic imaging problems including x-ray scatter imaging and optical scatter imaging for certain media. In all cases, noisy measurements are affected by both local scatter events…

Image and Video Processing · Electrical Eng. & Systems 2021-04-21 Michael R. Walker , Joseph A. O'Sullivan

Purpose: Neural network image reconstruction directly from measurement data is a relatively new field of research, that until now has been limited to producing small single-slice images (e.g., 1x128x128). This paper proposes a novel and…

Image and Video Processing · Electrical Eng. & Systems 2020-02-13 William Whiteley , Wing K. Luk , Jens Gregor

We propose Physics-Informed Fourier Networks for Electrical Properties (EP) Tomography (PIFON-EPT), a novel deep learning-based method for EP reconstruction using noisy and/or incomplete magnetic resonance (MR) measurements. Our approach…

One of the major challenges in design and developing of PET, scanners are the presence of inactive areas between the detector blocks which degrade the image spatial resolution and leads to streaking artifacts especially when we employ…

Medical Physics · Physics 2019-06-19 Isaac Shiri , Peyman Sheikhzadeh , Mohammad Reza Ay

Parameter-efficient tuning (PET) aims to transfer pre-trained foundation models to downstream tasks by learning a small number of parameters. Compared to traditional fine-tuning, which updates the entire model, PET significantly reduces…

Computer Vision and Pattern Recognition · Computer Science 2025-08-27 Kwonyoung Kim , Jungin Park , Jin Kim , Hyeongjun Kwon , Kwanghoon Sohn

An analytical method is presented with allows to estimate the energy resolution of time-of-flight neutron spectrometers, as well as its partial contributions, over a dynamical range that extends from the elastic line to the accessible…

Instrumentation and Detectors · Physics 2009-12-05 Ana M Gaspar

In this paper we prove that the choice of a suitable treatment of the scintillator surfaces, along with suitable photodetectors electronics and specific algorithms for raw data analysis, allow to achieve an optimal tradeoff between energy,…

Medical Physics · Physics 2012-03-02 Luigi Cosentino , Paolo Finocchiaro , Alfio Pappalardo , Franco Garibaldi

Positron emission tomography (PET) is the most sensitive biomedical imaging modality for non-invasively detecting and visualizing positron-emitting radiopharmaceuticals within a subject. In PET, measuring the time-of-flight (TOF)…

Instrumentation and Detectors · Physics 2024-10-17 Minseok Yi , Daehee Lee , Alberto Gola , Stefano Merzi , Michele Penna , Jae Sung Lee , Simon R. Cherry , Sun Il Kwon

Patient motion is well-known for degrading image quality during medical imaging. Especially positron emission tomography (PET) is susceptible to motion due to its usually long scan times. In hybrid PET/MRI (magnetic resonance imaging),…

Medical Physics · Physics 2019-05-21 Lynn Johann Frohwein , Florian Büther , Klaus Peter Schäfers

Positron emission tomography (PET) is widely used to assess metabolic activity, but its application is limited by the availability of radiotracers. 18F-labeled fluorodeoxyglucose (18F-FDG) is the most commonly used tracer but shows limited…

Image and Video Processing · Electrical Eng. & Systems 2025-06-24 Fang Chen , Weifeng Zhang , Xingyu Ai , BingXuan Li , An Li , Qiegen Liu

Photoacoustic computed tomography (PACT) is a non-invasive imaging modality, similar to ultrasound, with wide-ranging medical applications. Conventional PACT images are degraded by wavefront distortion caused by the heterogeneous speed of…

Image and Video Processing · Electrical Eng. & Systems 2025-08-05 Tianao Li , Manxiu Cui , Cheng Ma , Emma Alexander

This work is the second part of a simulation study investigating the processing of densely packed and moving granular assemblies by positron emission particle tracking (PEPT). Since medical PET scanners commonly used for PEPT are very…

Ultrasound attenuation is caused by absorption and scattering in tissue and is thus a function of tissue composition, hence its imaging offers great potential for screening and differential diagnosis. In this paper we propose a novel method…

Signal Processing · Electrical Eng. & Systems 2019-10-15 Richard Rau , Ozan Unal , Dieter Schweizer , Valery Vishnevskiy , Orcun Goksel

In this work, we present modeling and imaging performance of a dual panel limited-angle TOF-PET system for intraoperative surgical applications using GATE monte carlo toolkit. Several detector parameters such as detector pixel dimensions,…

Medical Physics · Physics 2024-02-13 Salar Sajedi , Yuemeng Feng , Hamid Sabet

Dynamic positron emission tomography (PET) images can reveal the distribution of tracers in the organism and the dynamic processes involved in biochemical reactions, and it is widely used in clinical practice. Despite the high effectiveness…

Image and Video Processing · Electrical Eng. & Systems 2025-12-22 Jie Sun , Junyan Zhang , Qian Xia , Chuanfu Sun , Yumei Chen , Yunjie Yang , Huafeng Liu , Wentao Zhu , Qiegen Liu

Combining dual-energy computed tomography (DECT) with positron emission tomography (PET) offers many potential clinical applications but typically requires expensive hardware upgrades or increases radiation doses on PET/CT scanners due to…

Medical Physics · Physics 2024-06-21 Siqi Li , Yansong Zhu , Benjamin A. Spencer , Guobao Wang
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