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The need for solving optimization problems is prevalent in a wide range of physical applications, including neuroscience, network design, biological systems, socio-economics, and chemical reactions. Many of these are classified as…

Plasmonic nanopores combine nanofluidic confinement with electromagnetic field enhancement, enabling optical interrogation of single molecules in sub-wavelength volumes. Yet, direct optical readout within these metallic geometries has…

Silicon Photomultipliers (SiPMs) are the state-of-the-art technology in single-photon detection with solid-state detectors. Single Photon Avalanche Diodes (SPADs), the key element of SiPMs, can now be manufactured in CMOS processes,…

Micro/nanoporous membranes have been used extensively in biological and medical applications associated with filtration, particle sorting, cell separation, and real-time sensing. Expanding its applications to microfluidics offers several…

The direct response of Silicon PhotoMultipliers being traversed by a MIP charged particle have been studied in a systematic way for the first time. Using beam test data, time resolution and the crosstalk probability have been measured. A…

Nanoparticle metrology has long been constrained by the assumption that, in mixed and unprocessed fluids, particle size, morphology, composition, and species-specific abundance cannot be resolved simultaneously from a single label-free…

The advent of nanoscale memristors raised hopes of being able to build CMOL (CMOS/nanowire/moLecular) type ultra-dense in-memory-computing circuit architectures. In CMOL, nanoscale memristors would be fabricated at the intersection of…

Emerging Technologies · Computer Science 2022-09-14 L. A. Camuñas-Mesa , E. Vianello , C. Reita , T. Serrano-Gotarredona , B. Linares-Barranco

Reproducing the exquisite ion selectivity displayed by biological ion channels in artificial nanopore systems has proven to be one of the most challenging tasks undertaken by the nanopore community, yet a successful achievement of this goal…

Supraparticles are coordinated assemblies of discrete nanoscale building blocks into complex and hierarchical colloidal superstructures. Holistic optical responses in such assemblies are not observed in an individual building block or in…

Protein phosphorylation provides a dynamic readout of cellular signaling yet remains difficult to detect at low abundance and stoichiometry. Single-molecule surface-enhanced Raman spectroscopy (SM-SERS) using particle-in-pore plasmonic…

Mesoscale and Nanoscale Physics · Physics 2026-04-09 Mulusew W. Yaltaye , Yingqi Zhao , Kuo Zhan , Vahid Farrahi , Jian-An Huang

Fast, volumetric imaging that integrates multiple imaging modalities is essential for probing dynamic, heterogeneous soft and biological matter. Here, we present the M3Scope, a simple yet versatile multiplane microscope that extends…

To bridge the gap between single/isolated pore systems to multi-pore systems, such as membranes/electrodes, we studied an array of nanochannels with varying interchannel spacing that controlled the degree of channel communication. Instead…

Fluid Dynamics · Physics 2015-01-29 Yoav Green , Sinwook Park , Gilad Yossifon

Removing hazardous particulate and macromolecular contaminants as well as viruses with sizes from a few nm up to the 100-nm-range from water and air is crucial for ensuring sufficient sanitation and hygiene for a growing world population.…

Materials Science · Physics 2021-09-03 Leiming Guo , Yong Wang , Martin Steinhart

Superconducting nanowire single-photon detectors (SNSPDs) with high timing resolution and low background counts in the mid infrared (MIR) have the potential to open up numerous opportunities in fields such as exoplanet searches, direct dark…

Analysis of nanoscale liquids, including wetting and flow phenomena, is a scientific challenge with far reaching implications for industrial technologies. We report the conception, development, and application of an integrated platform for…

Instrumentation and Detectors · Physics 2017-11-27 M. Engel , P. W. Bryant , R. F. Neumann , R. Giro , C. Feger , P. Avouris , M. Steiner

Significant inter-symbol interference (ISI) challenges the achievement of reliable, high data-rate molecular communication via diffusion. In this paper, a hybrid modulation based on pulse position and concentration is proposed to mitigate…

Information Theory · Computer Science 2021-04-21 Mustafa Can Gursoy , Daewon Seo , Urbashi Mitra

Spiking neurons can perform spatiotemporal feature detection by nonlinear synaptic and dendritic integration of presynaptic spike patterns. Multicompartment models of non-linear dendrites and related neuromorphic circuit designs enable…

Neural and Evolutionary Computing · Computer Science 2021-06-02 Mattias Nilsson , Foteini Liwicki , Fredrik Sandin

Optical metasurfaces have been recently explored as ultrathin analog image differentiators. By tailoring the momentum transfer function, they can perform efficient Fourier-filtering - and thus potentially any linear mathematical operation -…

Nanopores in 2D materials are of significant interest in advanced membrane technologies aimed at the sensing and separation of ions and molecules. These applications necessitate 2D nanopores that are precise in size and shape, and abundant…

Materials Science · Physics 2024-08-20 Dana O. Byrne , Frances I. Allen

Conventional silicon photomultipliers (SiPMs) are well established as light detectors with single-photon-detection capability and used throughout high energy physics, medical, and commercial applications. The possibility to produce single…

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