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Related papers: An Allen-Cahn tumor growth model with temperature

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We develop a multiphysics-based model to predict the response of localized tumors to combined-hyperthermia-radiotherapy (CHR) treatment. This procedure combines hyperthermia (tumor heating) with standard radiotherapy to improve efficacy of…

Tissues and Organs · Quantitative Biology 2019-07-05 Japan K. Patel , Richard Vasques , Barry D. Ganapol

In the present article the diffusion equation is used to model the spatio-temporal dynamics of a tumor, taking into account the heterogeneous of the medium. This approach makes it possible to take into account the complex geometric shape of…

Biological Physics · Physics 2023-02-07 Maxim V. Polyakov , Valeria V. Ten

We study the nonlinear stochastic heat equation in the spatial domain $\mathbb {R}$, driven by space-time white noise. A central special case is the parabolic Anderson model. The initial condition is taken to be a measure on $\mathbb {R}$,…

Probability · Mathematics 2015-12-22 Le Chen , Robert C. Dalang

We develop a linear fully discrete structure-preserving finite element method for a diffuse-interface model of tumour growth. The system couples a Cahn--Hilliard type equation with a nonlinear reaction-diffusion equation for nutrient…

Numerical Analysis · Mathematics 2025-10-23 Agus L. Soenjaya , Ping Lin , Thanh Tran

In this work, we present and analyse a system of coupled partial differential equations, which models tumour growth under the influence of subdiffusion, mechanical effects, nutrient supply, and chemotherapy. The subdiffusion of the system…

Analysis of PDEs · Mathematics 2021-10-08 Marvin Fritz , Christina Kuttler , Mabel L. Rajendran , Barbara Wohlmuth , Laura Scarabosio

We propose that domain walls formed in a classical Ginzburg-Landau model can exhibit topologically stable but thermodynamically metastable states. This proposal relies on Allen-Cahn's assertion that the velocity of domain wall is…

Statistical Mechanics · Physics 2024-05-21 Han-Qing Shi , Tian-Chi Ma , Hai-Qing Zhang

We investigate the long-time dynamics and optimal control problem of a diffuse interface model that describes the growth of a tumor in presence of a nutrient and surrounded by host tissues. The state system consists of a Cahn-Hilliard type…

Analysis of PDEs · Mathematics 2023-07-28 Cecilia Cavaterra , Elisabetta Rocca , Hao Wu

Mathematical modelling of tumor growth is one of the most useful and inexpensive approaches to determine and predict the stage, size and progression of tumors in realistic geometries. Moreover, these models has been used to get an insight…

Medical Physics · Physics 2017-08-01 Miguel Martín-Landrove

In this work, we investigate a fractional-order tumor growth model aimed at capturing memory effects and nonlocal temporal dynamics inherent to tumor evolution. The model is formulated using Caputo fractional derivatives and incorporates…

Medical Physics · Physics 2026-03-17 Karen Escutia , Carlos Islas , Pablo Padilla

In this paper we study a PDE-ODE system as a simplification of a Glioblastoma model. Mainly, we prove the existence and uniqueness of global in time classical solution using a fixed point argument. Moreover, we show some stability results…

Analysis of PDEs · Mathematics 2021-09-21 A. Fernández-Romero , F. Guillén-González , A. Suárez

We consider the heat equation with a logarithmic nonlinearity, on thereal line. For a suitable sign in front of the nonlinearity, weestablish the existence and uniqueness of solutions of the Cauchyproblem, for a well-adapted class of…

Analysis of PDEs · Mathematics 2020-12-16 Matthieu Alfaro , Rémi Carles

We present a new mathematical model of colorectal cancer growth and its response to monoclonal-antibody (mAb) therapy. Although promising, most mAb drugs are still in trial phases, and the possible variations in the dosing schedules of…

Cell Behavior · Quantitative Biology 2013-12-12 L. G. dePillis , H. Savage , A. E. Radunskaya

We review some recent extensions of the Ginzburg-Landau model able to describe several properties of non-conventional superconductors. In the first extension, s-wave superconductors endowed with two different critical temperatures are…

High Energy Physics - Phenomenology · Physics 2009-06-23 S. Esposito , G. Salesi

We present a robust computational framework for Hele-Shaw tumor growth with necrotic cores, a problem identified as the incompressible limit of the Porous Media Equation. Simulating this system presents a fundamental challenge: while the…

Numerical Analysis · Mathematics 2026-02-16 Yu Feng , Shuo Ling , Wenjun Ying , Zhennan Zhou

A general model for the ontogenetic growth of living organisms has been recently proposed. Here we investigate the extension of this model to the growth of solid malignant tumors. A variety of in vitro and in vivo data are analyzed and…

We analyze a system of cross-diffusion equations that models the growth of an avascular-tumor spheroid. The model incorporates two nonlinear diffusion effects, degeneracy type and super diffusion. We prove the global existence of weak…

Analysis of PDEs · Mathematics 2022-10-14 Samiha Belmor

In this paper, we study a phase field model for a tumor growth model of Cahn--Hilliard type in which the often assumed parabolic relaxation of the chemical potential is replaced by a hyperbolic one. We show that the resulting…

Analysis of PDEs · Mathematics 2026-02-16 Pierluigi Colli , Elisabetta Rocca , Jürgen Sprekels

We propose a PDE-ODE model for tissue regeneration, obtained by parabolic upscaling from kinetic transport equations written for the mesoscopic densities of mesenchymal stem cells and chondrocytes which evolve in an artificial scaffold…

Analysis of PDEs · Mathematics 2025-11-04 Shimi Chettiparambil Mohanan , Nishith Mohan , Christina Surulescu

We propose and study a strongly coupled PDE-ODE-ODE system modeling cancer cell invasion through a tissue network under the go-or-grow hypothesis asserting that cancer cells can either move or proliferate. Hence our setting features two…

Analysis of PDEs · Mathematics 2016-05-31 Anna Zhigun , Christina Surulescu , Alexander Hunt

In this paper we analyse a differential system related to a Glioblastoma growth. Using numerical simulations, we prove that model captures different kind of growth changing adequately the parameters of the model. Firstly, we make an…

Analysis of PDEs · Mathematics 2021-09-21 A. Fernández-Romero , F. Guillén-González , A. Suárez