Related papers: An Allen-Cahn tumor growth model with temperature
We consider a non-local tumour growth model of phase-field type, describing the evolution of tumour cells through proliferation in presence of a nutrient. The model consists of a coupled system, incorporating a non-local Cahn-Hilliard…
In this contribution, the non-local, integro-partial differential system of equations proposed by Hillen et al. (Bull. Math. Biol. 75, 2013, no.1, 161-184) to account for the the tumor growth paradox (or the observation that some incomplete…
We propose a mathematical model for the growth and treatment dynamics of Undifferentiated Pleomorphic Sarcoma (UPS) based on a system of nonlinear differential equations. The model integrates Gompertz-type tumor growth with surface-area…
In this paper we analyze a new temperature-dependent model for adhesive contact that encompasses nonlocal adhesive forces and damage effects, as well as nonlocal heat flux contributions on the contact surface. The related PDE system…
We extend previous works on the multiplicity of solutions to the Allen-Cahn system on closed Riemannian manifolds by considering an arbitrary number of phases. Specifically, we show that on parallelizable manifolds, the number of solutions…
Computational modeling of cancer can help unveil dynamics and interactions that are hard to replicate experimentally. Thanks to the advancement in cancer databases and data analysis technologies, these models have become more robust than…
This paper introduces a generalized matrix-valued Allen--Cahn model, where the unknown matrix-valued field belongs to $\mathbb{R}^{m_1\times m_2}$ with dimension $m_1\geq m_2$. By taking different values of $m_1$ and $m_2$, this model…
Theoretical and computational tools that can be used in the clinic to predict neoplastic progression and propose individualized optimal treatment strategies to control cancer growth is desired. To develop such a predictive model, one must…
We investigate the behavior, as a small parameter tends to zero, of a nonlocal Allen-Cahn equation. Given a rather general initial data, we perform a rigorous analysis of both the generation and the motion of interface, and obtain a new…
In this work, we present a phase-field model for tumour growth, where a diffuse interface separates a tumour from the surrounding host tissue. In our model, we consider transport processes by an internal, non-solenoidal velocity field. We…
In this paper we perform an asymptotic analysis for two different vanishing viscosity coefficients occurring in a phase field system of Cahn-Hilliard type that was recently introduced in order to approximate a tumor growth model. In…
We propose a new type of diffuse interface model describing the evolution of a tumor mass under the effects of a chemical substance (e.g., a nutrient or a drug). The process is described by utilizing the variables $\varphi$, an order…
Experimental results on amorphous ZrAlCu thin film growth and the dynamics of the surface morphology as predicted from a minimal nonlinear stochastic deposition equation are analysed and compared. Key points of this study are (i) an…
This is a preliminary announcement of results in the PhD. thesis of the first author concerning the nonlinear stochastic heat equation in the spatial domain $\R$, driven by space-time white noise. A central special case is the parabolic…
We consider weak solutions to a problem modeling tumor growth. Under certain conditions on the initial data, solutions can be obtained by passing to the stiff (incompressible) limit in a porous medium type problem with a Lotka-Volterra…
We present and analyze new multi-species phase-field mathematical models of tumor growth and ECM invasion. The local and nonlocal mathematical models describe the evolution of volume fractions of tumor cells, viable cells (proliferative and…
We consider a Gatenby--Gawlinski-type model of invasive tumors in the presence of an Allee effect. We describe the construction of bistable one-dimensional traveling fronts using singular perturbation techniques in different parameter…
We study one-dimensional viscoelastic phase transitions modeled by a Ginzburg--Landau energy with a non-convex cubic stress-strain law. Extending the isothermal model, we couple the momentum equation to a heat equation for the temperature…
We develop a PDE-based approach to the min-max construction of nontrivial integer rectifiable varifolds that are stationary with respect to anisotropic surface energies on closed Riemannian manifolds, in codimension one. Specifically, we…
In this paper we study a cross-diffusion system whose coefficient matrix is non-symmetric and degenerate. The system arises in the study of tissue growth with autophagy. The existence of a weak solution is established. We also investigate…