Related papers: An Allen-Cahn tumor growth model with temperature
Existing approaches to modeling the dynamics of brain tumor growth, specifically glioma, employ biologically inspired models of cell diffusion, using image data to estimate the associated parameters. In this work, we propose an alternative…
In this paper, we study a distributed optimal control problem for a diffuse interface model for tumor growth. The model consists of a Cahn-Hilliard type equation for the phase field variable coupled to a reaction diffusion equation for the…
Initiation and development of a malignant tumor is a complex phenomenon that has critical stages determining its long time behavior. This phenomenon is mathematically described by means of various models: from simple heuristic models to…
A simplified 2-D model which is an example of regional RF hyperthermia is presented. Human body is inside the wire with exciting current and the electromagnetic energy is concentrated within the tumor. The analyzed model is therefore a…
We formulate a Hele-Shaw type free boundary problem for a tumor growing under the combined effects of pressure forces, cell multiplication and active motion, the latter being the novelty of the present paper. This new ingredient is…
This paper is intended to tackle the control problem associated with an extended phase field system of Cahn-Hilliard type that is related to a tumor growth model. This system has been investigated in previous contributions from the…
In this paper, we investigate the tumor instability by employing both analytical and numerical techniques to validate previous results and extend the analytical findings presented in a prior study by Feng et al 2023. Building upon the…
The kinetics of chiral transitions in hot and dense quark matter is studied via a microscopic framework (Nambu-Jona-Lasinio model) and a phenomenological model (Ginzburg-Landau free energy). We focus on the far-from-equilibrium ordering…
In this paper, we propose a new mathematical model nonlinear reaction-diffusion PDE's describing the dynamics of propagation of cancer. Here the mixed problem for the proposed PDE's is investigated and by applying obtained results…
Heat-based cancer treatment, so-called hyperthermia, can be used to destroy tumour cells directly or to make them more susceptible to chemotherapy or radiation therapy. To apply heat locally, iron oxide nanoparticles are injected into the…
We propose a Ginzburg-Landau model for the expansion of a dodecahedral viral capsid during infection or maturation. The capsid is described as a dodecahedron whose faces, meant to model rigid capsomers, are free to move independent of each…
This paper is concerned with a fully nonlinear variant of the Allen-Cahn equation with strong irreversibility, where each solution is constrained to be non-decreasing in time. Main purposes of the paper are to prove the well-posedness,…
We report a model for hyperthermia therapies based on heat diffusion in a biological tissue containing a topological defect. Biological tissues behave like active liquid crystals with the presence of topological defects which are likely to…
We consider a phase-field model of prostate cancer growth with chemotherapy and antiangiogenic therapy effects which is introduced in [2]. It is comprised of phase-field equation to describe tumor growth, which is coupled to a…
We investigate the large time behavior of an agent based model describing tumor growth. The microscopic model combines short-range repulsion and cell division. As the number of cells increases exponentially in time, the microscopic model is…
We consider a phase-field system modelling solid tumour growth. This system consists of a Cahn-Hilliard equation coupled with a nutrient equation. The former is characterised by a degenerate mobility and a singular potential. Both equations…
We study the existence of weak solutions to a mixture model for tumour growth that consists of a Cahn--Hilliard--Darcy system coupled with an elliptic reaction-diffusion equation. The Darcy law gives rise to an elliptic equation for the…
We show that the correct entropy, temperature (and absorption probability) of non-extremal black p-brane can be reproduced by a certain thermodynamical model when maximizing its entropy. We show that the form of the model is related to the…
In this paper we study a model describing the growth of necrotic tumors in different regimes of vascularisation. The tumor consists of a necrotic core of death cells and a surrounding nonnecrotic shell. The corresponding mathematical…
Cancer is a disease that takes millions of lives every year. Then, to propose treatments, avoid recurrence, and improve the patient's life quality, we need to analyze this disease from a biophysical perspective with a solid mathematical…