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Segmenting curvilinear structures in medical images is essential for analyzing morphological patterns in clinical applications. Integrating topological properties, such as connectivity, improves segmentation accuracy and consistency.…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Zhuangzhi Gao , Feixiang Zhou , He Zhao , Xiuju Chen , Xiaoxin Li , Qinkai Yu , Yitian Zhao , Alena Shantsila , Gregory Y. H. Lip , Eduard Shantsila , Yalin Zheng

Recovering point clouds involves the sequential process of sampling and restoration, yet existing methods struggle to effectively leverage both topological and geometric attributes. To address this, we propose an end-to-end architecture…

Computer Vision and Pattern Recognition · Computer Science 2025-12-23 Kaiyue Zhou , Zelong Tan , Hongxiao Wang , Ya-Li Li , Shengjin Wang

Single-molecule localization microscopy generates point clouds corresponding to fluorophore localizations. Spatial cluster identification and analysis of these point clouds are crucial for extracting insights about molecular organization.…

Machine Learning · Computer Science 2025-12-12 Jesús Pineda , Sergi Masó-Orriols , Montse Masoliver , Joan Bertran , Mattias Goksör , Giovanni Volpe , Carlo Manzo

The properties of functional brain networks strongly depend on how their nodes are chosen. Commonly, nodes are defined by Regions of Interest (ROIs), pre-determined groupings of fMRI measurement voxels. Earlier, we have demonstrated that…

Neurons and Cognition · Quantitative Biology 2019-11-25 Elisa Ryyppö , Enrico Glerean , Elvira Brattico , Jari Saramäki , Onerva Korhonen

Modern deep neural networks have shown remarkable performance in medical image classification. However, such networks either emphasize pixel-intensity features instead of fundamental anatomical structures (e.g., those encoded by topological…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Pengfei Gu , Huimin Li , Haoteng Tang , Dongkuan , Xu , Erik Enriquez , DongChul Kim , Bin Fu , Danny Z. Chen

Surgical Scene Graphs abstract the complexity of surgical operating rooms (OR) into a structure of entities and their relations, but existing paradigms suffer from strictly dyadic structural limitations. Frameworks that predominantly rely…

Computer Vision and Pattern Recognition · Computer Science 2026-03-11 Tony Danjun Wang , Ka Young Kim , Tolga Birdal , Nassir Navab , Lennart Bastian

Retinal fundus photography enhancement is important for diagnosing and monitoring retinal diseases. However, early approaches to retinal image enhancement, such as those based on Generative Adversarial Networks (GANs), often struggle to…

Image and Video Processing · Electrical Eng. & Systems 2024-11-05 Xuanzhao Dong , Wenhui Zhu , Xin Li , Guoxin Sun , Yi Su , Oana M. Dumitrascu , Yalin Wang

In the segmentation of fine-scale structures from natural and biomedical images, per-pixel accuracy is not the only metric of concern. Topological correctness, such as vessel connectivity and membrane closure, is crucial for downstream…

Computer Vision and Pattern Recognition · Computer Science 2021-03-19 Xiaoling Hu , Yusu Wang , Li Fuxin , Dimitris Samaras , Chao Chen

Accurate quantification of the extent of lung pathological patterns (fibrosis, ground-glass opacity, emphysema, consolidation) is prerequisite for diagnosis and follow-up of interstitial lung diseases. However, segmentation is challenging…

Image and Video Processing · Electrical Eng. & Systems 2025-01-08 Rezkellah Noureddine Khiati , Pierre-Yves Brillet , Radu Ispas , Catalin Fetita

Topology identification (TI) is a key task for state estimation (SE) in distribution grids, especially the one with high-penetration renewables. The uncertainties, initiated by the time-series behavior of renewables, will almost certainly…

Applications · Statistics 2023-12-12 Xing He , Robert Qiu , Qian Ai , Tianyi Zhu

The vast volume of medical image data necessitates efficient compression techniques to support remote healthcare services. This paper explores Region of Interest (ROI) coding to address the balance between compression rate and image…

Image and Video Processing · Electrical Eng. & Systems 2025-01-07 Utkarsh Prakash Srivastava , Toshiaki Fujii

Designing strong and robust bio-inspired structures requires an understanding of how function arises from the architecture and geometry of materials found in nature. We draw from trabecular bone, a lightweight bone tissue that exhibits a…

Biological Physics · Physics 2019-10-09 Chantal Nguyen , Darin Peetz , Ahmed E. Elbanna , Jean M. Carlson

Accurate and interpretable brain tumor classification from medical imaging remains a challenging problem due to the high dimensionality and complex structural patterns present in magnetic resonance imaging (MRI). In this study, we propose a…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Faisal Ahmed

This paper proposes a novel topological learning framework that integrates networks of different sizes and topology through persistent homology. Such challenging task is made possible through the introduction of a computationally efficient…

Neurons and Cognition · Quantitative Biology 2023-01-30 Tananun Songdechakraiwut , Moo K. Chung

Medical image segmentation is a critical component of clinical workflows, enabling accurate diagnosis, treatment planning, and disease monitoring. However, despite the superior performance of transformer-based models over convolutional…

Computer Vision and Pattern Recognition · Computer Science 2026-02-10 Thuraya Alzubaidi , Sana Ammar , Maryam Alsharqi , Islem Rekik , Muzammil Behzad

Motivation: Understanding the spatial architecture of tissues is essential for decoding the complex interactions within cellular ecosystems and their implications for disease pathology and clinical outcomes. Recent advances in multiplex…

Quantitative Methods · Quantitative Biology 2025-04-28 Junsouk Choi , Jian Kang , Veerabhadran Baladandayuthapani

Navigating topological transitions in cellular mechanical systems is a significant challenge for existing simulation methods. While abstract models lack predictive capabilities at the cellular level, explicit network representations…

Graphics · Computer Science 2024-04-30 Logan Numerow , Yue Li , Stelian Coros , Bernhard Thomaszewski

Images with abnormal brain anatomy produce problems for automatic segmentation techniques, and as a result poor ROI detection affects both quantitative measurements and visual assessment of perfusion data. This paper presents a new approach…

Image and Video Processing · Electrical Eng. & Systems 2019-02-19 Svitlana M Alkhimova

Deep learning has been recently applied to a multitude of computer vision and medical image analysis problems. Although recent research efforts have improved the state of the art, most of the methods cannot be easily accessed, compared or…

Computer Vision and Pattern Recognition · Computer Science 2018-04-26 Fausto Milletari , Johann Frei , Seyed-Ahmad Ahmadi

Transistor topology optimization is a critical step in standard cell design, directly dictating diffusion sharing efficiency and downstream routability. However, identifying optimal topologies remains a persistent bottleneck, as…

Machine Learning · Computer Science 2026-04-17 Zhan Song , Yu-Tung Liu , Chen Chen , Guoheng Sun , Jiaqi Yin , Chia-tung Ho , Ang Li , Haoxing Ren , Cunxi Yu