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Multi-agent systems (MAS) are increasingly used in healthcare to support complex decision-making through collaboration among specialized agents. Because these systems act as collective decision-makers, they raise challenges for trust,…

Artificial Intelligence · Computer Science 2026-03-24 Truong Thanh Hung Nguyen , Hélène Fournier , Piper Jackson , Makoto Itoh , Shannon Freeman , Rene Richard , Hung Cao

Recent large language models (LLMs) have demonstrated significant advancements, particularly in their ability to serve as agents thereby surpassing their traditional role as chatbots. These agents can leverage their planning and tool…

Machine Learning · Computer Science 2025-02-13 Yixing Jiang , Kameron C. Black , Gloria Geng , Danny Park , James Zou , Andrew Y. Ng , Jonathan H. Chen

Multi-agent debate (MAD) has recently emerged as a promising framework for improving the reasoning performance of large language models (LLMs). Yet, whether LLM agents can genuinely engage in deliberative reasoning, beyond simple ensembling…

Multiagent Systems · Computer Science 2025-11-12 Haolun Wu , Zhenkun Li , Lingyao Li

Medicine is inherently pluralistic. Principles such as autonomy, beneficence, nonmaleficence, and justice routinely conflict, and such ethical dilemmas often sharply divide reasonable physicians. Good clinical practice navigates these…

We study a class of emergent misalignment in multi-agent systems (MAS), with a focus on automated workflows, which we refer to agentic misalignment. Although these systems can solve complex tasks, they often fail because agents act…

Artificial Intelligence · Computer Science 2026-05-26 Wenqian Ye , Bo Yuan , Zhichao Xu , Yijun Tian , Yawei Wang , Henry Kautz , Aidong Zhang

Multi-agent large language model (LLM) systems have shown promise for solving complex tasks through agent collaboration. However, existing frameworks assign tasks based on predefined roles without considering whether an agent can accurately…

Artificial Intelligence · Computer Science 2026-05-19 Chenyu Wang , Yang Shu

Clinical decision making (CDM) is a complex, dynamic process crucial to healthcare delivery, yet it remains a significant challenge for artificial intelligence systems. While Large Language Model (LLM)-based agents have been tested on…

Computation and Language · Computer Science 2025-10-13 Jie Liu , Wenxuan Wang , Zizhan Ma , Guolin Huang , Yihang SU , Kao-Jung Chang , Wenting Chen , Haoliang Li , Linlin Shen , Michael Lyu

LLM agents are increasingly deployed to plan, retrieve, and write with tools, yet evaluation still leans on static benchmarks and small human studies. We present the Agent-Testing Agent (ATA), a meta-agent that combines static code…

Computation and Language · Computer Science 2025-08-26 Sameer Komoravolu , Khalil Mrini

As autonomous AI agents are increasingly deployed in high-stakes environments, ensuring their safety and alignment with human values is becoming a practical deployment concern. Current benchmarks for AI agents primarily evaluate refusal of…

Artificial Intelligence · Computer Science 2026-05-12 Miles Q. Li , Benjamin C. M. Fung , Martin Weiss , Pulei Xiong , Khalil Al-Hussaeni , Claude Fachkha

Decision conferences are structured, collaborative meetings that bring together experts from various fields to address complex issues and reach a consensus on recommendations for future actions or policies. These conferences often rely on…

Computation and Language · Computer Science 2025-07-14 Selina Heller , Mohamed Ibrahim , David Antony Selby , Sebastian Vollmer

Artificial intelligence has significantly advanced healthcare, particularly through large language models (LLMs) that excel in medical question answering benchmarks. However, their real-world clinical application remains limited due to the…

Computation and Language · Computer Science 2024-07-01 Zhihao Fan , Jialong Tang , Wei Chen , Siyuan Wang , Zhongyu Wei , Jun Xi , Fei Huang , Jingren Zhou

Large Language Model (LLM)-based agents that plan, use tools and act has begun to shape healthcare and medicine. Reported studies demonstrate competence on various tasks ranging from EHR analysis and differential diagnosis to treatment…

Artificial Intelligence · Computer Science 2026-02-05 Shubham Vatsal , Harsh Dubey , Aditi Singh

Artificial intelligence safety research focuses on aligning individual language models with human values, yet deployed AI systems increasingly operate as interacting populations where social influence may override individual alignment. Here…

Physics and Society · Physics 2026-05-12 Giordano De Marzo , Alessandro Bellina , Claudio Castellano , Viola Priesemann , David Garcia

Detecting biases in the outputs produced by generative models is essential to reduce the potential risks associated with their application in critical settings. However, the majority of existing methodologies for identifying biases in…

Computation and Language · Computer Science 2025-02-04 Erica Coppolillo , Giuseppe Manco , Luca Maria Aiello

Endoscopic diagnosis is an iterative process in which clinicians progressively acquire, compare, and verify local visual evidence before reaching a conclusion. Current AI systems do not adequately support this process because fine-grained…

Artificial Intelligence · Computer Science 2026-05-19 Yi Tang , Kai-Ni Wang , Yang Chen , Xiaopu He , Guangquan Zhou

As large language models transition from text-based interfaces to audio interactions in clinical settings, they might introduce new vulnerabilities through paralinguistic cues in audio. We evaluated these models on 170 clinical cases, each…

Computation and Language · Computer Science 2025-11-11 Zhi Rui Tam , Yun-Nung Chen

Large language models applied to clinical prediction exhibit case-level heterogeneity: simple cases yield consistent outputs, while complex cases produce divergent predictions under minor prompt changes. Existing single-agent strategies…

Artificial Intelligence · Computer Science 2026-04-02 Yuxing Lu , Yushuhong Lin , Jason Zhang

Diagnostic errors in healthcare persist as a critical challenge, with increasing numbers of patients turning to online resources for health information. While AI-powered healthcare chatbots show promise, there exists no standardized and…

Artificial Intelligence · Computer Science 2024-12-18 Deep Bhatt , Surya Ayyagari , Anuruddh Mishra

Multi-agent deliberation systems using large language models (LLMs) are increasingly proposed for policy simulation, yet they suffer from artificial consensus: evaluator agents converge on the same option regardless of their assigned value…

Multiagent Systems · Computer Science 2026-04-30 Ariel Sela

While large language models are capable diagnostic tools, the impact of multi-agent topology on diagnostic accuracy remains underexplored. This study evaluates four agent topologies, Control (single agent), Hierarchical, Adversarial, and…

Multiagent Systems · Computer Science 2026-03-10 Ahmed Almasoud