English

One Panel Does Not Fit All: Case-Adaptive Multi-Agent Deliberation for Clinical Prediction

Artificial Intelligence 2026-04-02 v1 Computation and Language Multiagent Systems

Abstract

Large language models applied to clinical prediction exhibit case-level heterogeneity: simple cases yield consistent outputs, while complex cases produce divergent predictions under minor prompt changes. Existing single-agent strategies sample from one role-conditioned distribution, and multi-agent frameworks use fixed roles with flat majority voting, discarding the diagnostic signal in disagreement. We propose CAMP (Case-Adaptive Multi-agent Panel), where an attending-physician agent dynamically assembles a specialist panel tailored to each case's diagnostic uncertainty. Each specialist evaluates candidates via three-valued voting (KEEP/REFUSE/NEUTRAL), enabling principled abstention outside one's expertise. A hybrid router directs each diagnosis through strong consensus, fallback to the attending physician's judgment, or evidence-based arbitration that weighs argument quality over vote counts. On diagnostic prediction and brief hospital course generation from MIMIC-IV across four LLM backbones, CAMP consistently outperforms strong baselines while consuming fewer tokens than most competing multi-agent methods, with voting records and arbitration traces offering transparent decision audits.

Keywords

Cite

@article{arxiv.2604.00085,
  title  = {One Panel Does Not Fit All: Case-Adaptive Multi-Agent Deliberation for Clinical Prediction},
  author = {Yuxing Lu and Yushuhong Lin and Jason Zhang},
  journal= {arXiv preprint arXiv:2604.00085},
  year   = {2026}
}
R2 v1 2026-07-01T11:46:58.642Z