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Machine learning force fields (MLFFs) are a promising approach to balance the accuracy of quantum mechanics with the efficiency of classical potentials, yet selecting an optimal model amid increasingly diverse architectures that delivers…

Machine Learning · Computer Science 2025-12-09 Bangchen Yin , Yue Yin , Yuda W. Tang , Hai Xiao

Molecular dynamics (MD) simulations are essential tools for unraveling atomistic insights into the structure and dynamics of condensed-phase systems. However, the universal and accurate prediction of macroscopic properties from ab initio…

Quantum machine learning (QML) is a promising early use case for quantum computing. There has been progress in the last five years from theoretical studies and numerical simulations to proof of concepts. Use cases demonstrated on…

Quantum Physics · Physics 2024-04-30 Daniel Goldsmith , M M Hassan Mahmud

Learning on small data is a challenge frequently encountered in many real-world applications. In this work we study how effective quantum ensemble models are when trained on small data problems in healthcare and life sciences. We…

Methods of computational quantum chemistry provide accurate approximations of molecular properties crucial for computer-aided drug discovery and other areas of chemical science. However, high computational complexity limits the scalability…

Quantum Biology is emerging as a new field at the intersection between fundamental physics and biology, promising novel insights into the nature and origin of biological order. We discuss several elements of QBCL (Quantum Biology at…

Other Quantitative Biology · Quantitative Biology 2013-04-04 Michael Bordonaro , Vasily Ogryzko

The Research & Development (R&D) phase of drug development is a lengthy and costly process. To revolutionize this process, we introduce our new concept QMLS to shorten the whole R&D phase to three to six months and decrease the cost to…

Biomolecules · Quantitative Biology 2024-09-06 Yifan Zhou , Yan Shing Liang , Yew Kee Wong , Haichuan Qiu , Yu Xi Wu , Bin He

Quantum machine learning (QML) is a fast-growing discipline within quantum computing. One popular QML algorithm, quantum kernel estimation, uses quantum circuits to estimate a similarity measure (kernel) between two classical feature…

Quantum Physics · Physics 2023-07-12 Travis L. Scholten , Derrick Perry , Joseph Washington , Jennifer R. Glick , Thomas Ward

Our understanding of the physics of biological molecules, such as proteins and DNA, is limited because the approximations we usually apply to model inert materials are not in general applicable to soft, chemically inhomogeneous systems. The…

Quantum Physics · Physics 2010-07-13 Sarah Harris , Vivien M. Kendon

Quantum technologies are rapidly advancing as image classification tasks grow more complex due to large image volumes and extensive parameter updates required by traditional machine learning models. Quantum Machine Learning (QML) offers a…

Quantum Physics · Physics 2025-04-29 Md Farhan Shahriyar , Gazi Tanbhir

Scientific figure interpretation is a crucial capability for AI-driven scientific assistants built on advanced Large Vision Language Models. However, current datasets and benchmarks primarily focus on simple charts or other relatively…

Longitudinal biomedical studies play a vital role in tracking disease progression, treatment response, and the emergence of resistance mechanisms, particularly in complex disorders such as cancer and neurodegenerative diseases. However, the…

Quantitative Methods · Quantitative Biology 2025-04-28 Maria Demidik , Filippo Utro , Alexey Galda , Karl Jansen , Daniel Blankenberg , Laxmi Parida

Label-free cell classification is advantageous for supplying pristine cells for further use or examination, yet existing techniques frequently fall short in terms of specificity and speed. In this study, we address these limitations through…

Image and Video Processing · Electrical Eng. & Systems 2025-02-25 Khayrul Islam , Ratul Paul , Shen Wang , Yuwen Zhao , Partho Adhikary , Qiying Li , Xiaochen Qin , Yaling Liu

Practical Quantum Machine Learning (QML) is challenged by noise, limited scalability, and poor trainability in Variational Quantum Circuits (VQCs) on current hardware. We propose a multi-chip ensemble VQC framework that systematically…

Machine Learning · Computer Science 2025-05-21 Junghoon Justin Park , Jiook Cha , Samuel Yen-Chi Chen , Huan-Hsin Tseng , Shinjae Yoo

Quantum software testing has attracted interest in recent years, prompting the development of various techniques to automate the testing of quantum software. These techniques generate test cases that must be assessed for their effectiveness…

Software Engineering · Computer Science 2026-04-20 Eñaut Mendiluze Usandizaga , Thomas Laurent , Paolo Arcaini , Shaukat Ali

Quantum Error Correction (QEC) is one of the fundamental problems in quantum computer systems, which aims to detect and correct errors in the data qubits within quantum computers. Due to the presence of unreliable data qubits in existing…

Quantum Physics · Physics 2024-04-08 Yue Zhao

Quantum federated learning (QFL) is a novel framework that integrates the advantages of classical federated learning (FL) with the computational power of quantum technologies. This includes quantum computing and quantum machine learning…

Networking and Internet Architecture · Computer Science 2023-10-24 Mahdi Chehimi , Samuel Yen-Chi Chen , Walid Saad , Don Towsley , Mérouane Debbah

The ability to perform ab initio molecular dynamics simulations using potential energies calculated on quantum computers would allow virtually exact dynamics for chemical and biochemical systems, with substantial impacts on the fields of…

Quantum machine learning has the potential to computationally outperform classical machine learning, but it is not yet clear whether it will actually be valuable for practical problems. While some artificial scenarios have shown that…

Quantum Physics · Physics 2025-08-22 Akimoto Nakayama , Kosuke Mitarai , Leonardo Placidi , Takanori Sugimoto , Keisuke Fujii

Machine learning force fields (MLFFs) have revolutionized molecular simulations by providing quantum mechanical accuracy at the speed of molecular mechanical computations. However, a fundamental reliance of these models on fixed-cutoff…

Chemical Physics · Physics 2026-01-08 Chu Wang , Lin Huang , Xinran Wei , Tao Qin , Arthur Jiang , Lixue Cheng , Jia Zhang
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